Listar QO - Contribuciones a congresos científicos por título
Mostrando ítems 6-25 de 63
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Dendrímeros antigénicos sobre partículas de sílica para determinar IgE específicas de antibióticos betalactámicos
Matamoros Castellano, Esther; Jiménez, Isabel M.; Gil-Ocaña, Violeta; Mayorga Mayorga, Cristobalina; Doña, Inmaculada; Céspedes Lagos, José Antonio; Montañez-Vega, María Isabel
; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel; Torres-Cazorla, María Isabel[et al.] (2022)
Los inmunoensayos empleados para el diagnóstico in vitro de alergias a antibióticos betalactámicos actualmente presentan una limitada sensibilidad y pobre especificidad, además de no estar disponibles de forma comercial ... -
Dendrimers-modified solid supports: towards nanostructures materials for clinical diagnostic
Vida-Pol, Yolanda; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Montañe, M I; Pérez-de-Inestrosa-Villatoro, Ezequiel; Ruiz-Sanchez, Antonio Jesus[et al.] (2013-09-25)
The design and synthesis of new materials for biomedical applications is a high-priority research topic in a number of biomedical areas. The rapid development of nanotechnology over the past few decades has created wide ... -
Design and synthesis of new dendrons for biomedical applications
Dendrons are excellent multifunctional platforms for many different applications. In particular, the development of multivalent molecular nanostructures, with a well-defined size and shape, has an enormous interest in the ... -
Design and synthesis of new molecules based on indolium derivatives for two-photon absorption bioimaging applications
Benítez-Martín, Carlos; Nájera-Albendín, Francisco; Pérez-de-Inestrosa-Villatoro, Ezequiel (2018-11-15)
Bioimaging is the visualization of biological processes in real time, interfering as less as possible with these and using non-invasive methods. Among others, fluorescence methods have acquired a very important role in ... -
Design of multi-haptenized dendrimeric-antigens for in vitro IgE recognition
Nájera-Albendín, Francisco; Montañez-Vega, María Isabel; Ruiz-Sanchez, Antonio Jesus; Vida-Pol, Yolanda; Collado-Martín, Daniel; Pérez-de-Inestrosa-Villatoro, Ezequiel; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa; Blanca Gómez, Miguel[et al.] (2014-06-12)
Reactions mediated by the Immunoglobulin E (IgE) involved a high number of allergic drug responses, ranging from simple skin symptoms to anaphylactic shock.1 In order to emulate the recognition process working in vivo, ... -
Detecting hydroxyl radical with a new two-photon fluorescent probe in living cells
Nájera-Albendín, Francisco; Benítez-Martín, Carlos; Guadix-Domínguez, Juan Antonio; Pérez-Pomares, José María; Pérez-de-Inestrosa-Villatoro, Ezequiel (Real Sociedad Española de Química, 2018-06-20)
Reactive oxygen species (ROS) are known to be involved in the onset and development of multiple diseases, including cancer, cardiovascular diseases, neurodegenerative diseases and diabetes among others. Generation of ROS ... -
Diastereoselective synthesis of chiral amines by imines alkylation
Díaz-Morilla, Amelia; Muñoz, Carmen; Sánchez, María; Valpuesta-Fernández, María (2013-10-03)
En esta comunicación se aborda la síntesis de aminas quirales utilizando como agente alquilante trietilborano. -
Direct characterization of functional materials by haptenized fluorescent dendrimers for in vitro allergic drug diagnose
Ruiz-Sanchez, Antonio Jesus; Collado-Martín, Daniel; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa; Pérez-de-Inestrosa-Villatoro, Ezequiel (2020-10-01)
β-lactams are the most widely drug prescribed against infections, but they are the most commonly reported medication allergy too. A correct diagnosis of these allergic reactions is crucial to avoid rejecting them by other ... -
Diseño de dendrímeros amino-terminales basados en enlaces tipo amidas. Estructuras con menor repulsión estérica y síntesis a gran escala
Pérez-de-Inestrosa-Villatoro, Ezequiel; Nájera-Albendín, Francisco; Morgado, Anjara; Vida-Pol, Yolanda (2022-05-30)
La estructura ramificada y la elevada multivalencia que presentan los dendrímeros los convierten en excelentes compuestos con potenciales aplicaciones en el campo de la biomedicina. En concreto, los dendrímeros con grupos ... -
Diseño y síntesis de nuevos dendrímeros
Morgado, Anjara; Molina, Noemi; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2018-03-06)
Los dendrímeros son excelentes plataformas multifuncionales para una gran cantidad de diferentes aplicaciones. En particular, el desarrollo de nanoestructuras moleculares multivalentes, con tamaño y forma bien definida, ... -
Diseño y síntesis de nuevos dendrímeros y dendrones. Aplicaciones en regeneración tisular
Vida-Pol, Yolanda; Molina, Noemi; Morgado, Anjara; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2018-03-06)
Los dendrímeros han generado un enorme interés debido a su particular estructura ramificada y su multivalencia. La extensa investigación que se ha llevado a cabo sobre este tipo de macromoléculas ha demostrado la naturaleza ... -
Diseño y síntesis de nuevos dendrones para aplicaciones biomédicas
Molina, Noemi; Morgado, Anjara; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2018-03-06)
Los dendrímeros han sido empleados en una gran variedad de aplicaciones, entre las que destacan las del campo de la biomedicina. Estas macromoléculas multivalentes ofrecen la posibilidad de incorporar múltiples funcionalidades ... -
Energy transfer in Aminonaphthalimide-BODIPY dyads upon one and two photons excitation
Collado-Martín, Daniel; Vida-Pol, Yolanda; Nájera-Albendín, Francisco; Pérez-de-Inestrosa-Villatoro, Ezequiel (2014-07-03)
BODIPY dyes are nowadays widely commercialized chromophores that have attracted immense interest as versatile tools in biological chemistry [1]. However, the generally very small Stokes shifts of BODIPY dyes may cause ... -
Fijación de dendrímeros antigénicos en superficies para determinación de IgE
Vida-Pol, Yolanda; Montañez-Vega, María Isabel; Mesa, Pablo; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2016-02-15)
Actualmente, el diseño de nuevos materiales con potenciales aplicaciones biomédicas es de gran importancia , sobre todo para su uso directo en diagnóstico clínico . En particular, los dispositivos que ... -
Glycomimetic Ligands for C-type Lectin Recognition.
(2023)C-type lectin receptors (CLRs) represent pivotal sensory mechanisms orchestrating the primary immune response via dendritic cells.1 The exploration of non-native ligands as molecular tools for the manipulation of CLRs has ... -
Hybrid pH-Responsive Au@p4VP Microgels as Platform for Selective SERS Analysis
(2017-09-21)We present the synthesis a of pH-responsive core@shell hybrid microgel. This colloidal system is formed by a 55 nm Au core individually covered by a polymeric pH-sensitive shell of poly(4-vinylpyridine), that we denote as ... -
Intramolecular [3+2] cycloaddition of azido-unsaturated esters derived of monosaccharides
Pino-González, María Soledad; Romero-Carrasco, Antonio; Calvo-Losada, Saturnino; Quirante-Sánchez, José Joaquín (2013-11-05)
Iminosugars have been shown to be very potent inhibitors of glycosidases and glycolsyltransferases. Due to their ability to resemble the transition states of the sugars involved in these processes, a variety of m onocyclic ... -
Intramolecular [3+2] Cycloaddition of Fused Azolo-Azepanes from Azido Monosaccharides Derivatives
Pino-González, María Soledad; Romero-Carrasco, Antonio; Calvo-Losada, Saturnino; Quirante-Sánchez, José Joaquín (Centro Investigaciones Biológicas, 2016)
Síntesis de bicíclicos compuestos empleando epoxiamidas como material de partida. Obtención de tetrazolo azepanos con posible actividad biológica. -
Lipid and Janus nanoparticles for active delivery
López-Romero, Juan Manuel (2014-06-12)
The following synthesis is based on the paper „Production of large quantities of „Janus“ nanoparticles using wax-in-water emulsions“ published by Ravaine et al.[1]In two beakers, 0.2 g of the synthesized silica particles ... -
Managing with (fluorescent)-biomimetic dendrimers
Pérez-de-Inestrosa-Villatoro, Ezequiel; Vida-Pol, Yolanda; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Mesa-Antunez, Pablo; Ruiz-Sanchez, Antonio Jesus; Molina, Noemi; Morgado, Anjara[et al.] (2017-06-30)
Dendrimers that are modified through their peripheral groups have been employed for many biomedical purposes. Diagnosis via specific interactions with target proteins is one of the objectives that has been given more ...