Listar QO - Artículos por título
Mostrando ítems 31-48 de 48
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Photophysical properties and bioimaging application of an aminonaphthalimide-squaraine non-conjugated system
Stamentović, Vladimir; Collado-Martín, Daniel
; Pérez-de-Inestrosa-Villatoro, Ezequiel (ELSEVIER, 2022-02-15)
An aminonaphthalimide-squaraine non-conjugated system was designed and synthetized with the purpose of preparing fluorescent molecule in the 650–700 nm region that could operate via energy transfer (ET) between covalently ... -
Rapid amplitude-modulation of a diarylethene photoswitch: En route to contrast-enhanced fluorescence imaging
(The Royal Society of Chemistry, 2021)A water soluble diarylethene (DAE) derivative that displays exceptionally intense fluorescence from the colorless open form has been synthesized and characterized using UV/vis spectroscopy and fluorescence microscopy. ... -
Slightly congested amino terminal dendrimers. The synthesis of amide-based stable structures on a large scale.
Morgado Benítez, Anjara; Nájera-Albendín, Francisco; Lagunas, Anna; Samitier, Josep; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (Royal Society of Chemistry, 2021-08-17)
Nowadays, amino terminal dendrimers are appealing materials for biological applications due to their multivalence and the versatile conjugation of the amino groups. However, the high reactivity of these terminal groups can ... -
Solid phase synthesis of globomycin and SF-1902 A5
The syntheses of the natural lipocyclodepsipeptide-type antibiotics globomycin and SF-1902 A5 are reported utilizing solid phase technology for the construction of the peptidic fragment and a new asymmetric methodology of ... -
SPION Nanoparticles for Delivery of Dopaminergic Isoquinoline and Benzazepine Derivatives.
Lucena-Serrano, Cristina; Lucena-Serrano, Ana; Díaz-Morilla, Amelia; Valpuesta-Fernández, María; Villaverde, Gonzalo; López-Romero, Juan Manuel; Sarabia-García, Francisco Ramón; Laurenti, Marco; Rubio Retama, Jorge; Contreras-Cáceres, Rafael[et al.] (Elsevier, 2022-06-27)
Superparamagnetic iron nanoparticles (SPIONs) have become one of the most useful colloidal systems in nanomedicine. We report here the preparation of new hybrid core@shell systems based on SPION nanoparticles coated with ... -
Stereoselective total synthesis of (-)-Depudecin
The total synthesis of the natural product depudecin, an antiangiogenic microbial polyketide with inhibitory activity against histone deacetylases, is reported. Characterized by a highly oxidized 11-carbon chain containing ... -
Synthesis and Antitumor Activity Evaluation of Compounds Based on Toluquinol
Cheng-Sánchez, Iván; Torres-Vargas, José Antonio; Martínez-Póveda, Beatriz Amparo; Guerrero Vásquez, Guillermo A.; Medina, Miguel Ángel; Sarabia-García, Francisco Ramón; Quesada, Ana R.[et al.] (MDPI, 2019-08-23)
Encouraged by the promising antitumoral, antiangiogenic, and antilymphangiogenic properties of toluquinol, a set of analogues of this natural product of marine origin was synthesized to explore and evaluate the effects of ... -
Synthesis and dopaminergic activity of a series of new 1-aryl tetrahydroisoquinolines and 2-substituted 1-aryl-3-tetrahydrobenzazepines.
Lucena-Serrano, Cristina; Lucena-Serrano, Ana; Rivera-Ramírez, Alicia; López-Romero, Juan Manuel; Valpuesta-Fernández, María; Díaz-Morilla, Amelia[et al.] (Elsevier, 2018-07-05)
A series of new 1-aryl-6,7-dihydroxy tetrahydroisoquinolines with several substitution patterns in the 1-aryl group at C-1 were prepared in good yields. The influence of each substituent on the affinity and selectivity for ... -
Synthesis of (-)- and (+)-Gummiferol via Asymmetric Synthesis of Glycidic Amides.
García-Ruiz, Cristina; Cheng-Sánchez, Iván; Sarabia-García, Francisco Ramón (Thieme, 2016)
An efficient synthesis of the natural product (–)-gummiferol is achieved according to a novel asymmetric methodology of epoxide formation based on a new class of chiral sulfonium salts. This new methodology allows the rapid ... -
Synthesis of (-)-cannabidiol (CBD),(-)-Δ9- and(-)--Δ8-tetrahydrocannabinols, encapsulation of CBD with nanoparticles for controlled delivery and biological evaluation
Moya-Utrera, Federico; Fuentes-Ríos, David; Romero-Carrasco, Antonio; Doña Flores, Manuel; Cheng-Sánchez, Iván; Díaz-Morilla, Amelia; Pino-González, María Soledad; Martínez-Férez, Antonio; Moreno, Javier; Mesas, Cristina; Melguizo, Consolación; Prados, José; Sarabia-García, Francisco Ramón; López-Romero, Juan Manuel[et al.] (Wiley, 2024-12)
Cannabidiol (CBD) is garnering increasing interest due to its significant biological activity. This natural compound is one of the major cannabinoids in Cannabis sativa L. In this work, we describe the encapsulation of CBD ... -
Synthesis of Amino Terminal Clicked dendrimers. Approaches to the application as a biomarker
Molina, Noemí; Nájera-Albendín, Francisco; Guadix-Domínguez, Juan Antonio; perez-pomarez, Jose M; Vida-Pol, Yolanda; Perez-Inestrosa, Ezequiel[et al.] (ACS Publications, 2019)
Herein, we present an easy and efficient synthesis of amino terminal dendrons, combining protection/deprotection reactions with copper-catalyzed azide alkyne cycloaddition in a convergent way. This new approach affords ... -
Synthesis, characterization and antitumor activity of a poly-4-Vinyl pyridine-co-cannabidiol polymer
Fuentes-Ríos, David; Moya-Utrera, Federico; Moreno, Javier; Mesas, Cristina; Doña Flores, Manuel; Sarabia-García, Francisco Ramón; López-Romero, Juan Manuel; Melguizo, Consolación; Prados, José[et al.] (Elsevier, 2024)
Due to its natural origin and numerous beneficial properties, cannabidiol (CBD), one of the major phytocannabinoids of the Cannabis sativa L., has attracted the attention of many research groups in recent years. In this ... -
The Development of the Bengamides as New Antibiotics against Drug-Resistant Bacteria
Porras Alcalá, Cristina; Moya-Utrera, Federico; García-Castro, Miguel; Sánchez-Ruiz, Antonio; López-Romero, Juan Manuel; Pino-González, María Soledad; Díaz-Morilla, Amelia; Kitamura, Seiya; W. Wolan, Dennis; Prados, Jose; Melguizo, Consolación; Cheng-Sánchez, Iván; Sarabia-García, Francisco Ramón[et al.] (IOAP-MPDI, 2022-05-31)
The bengamides comprise an interesting family of natural products isolated from sponges belonging to the prolific Jaspidae family. Their outstanding antitumor properties, coupled with their unique mechanism of action and ... -
The Role of Benzylpenicilloyl Epimers in Specific IgE Recognition
Mayorga, Cristobalina; Montañez-Vega, María Isabel; Nájera-Albendín, Francisco; Bogas Herrera, Gádor; Rodriguez Gil, David; Palacios, Ricardo; Torres-Jaén, María Josefa; Vida-Pol, Yolanda; Perez-Inestrosa, Ezequiel[et al.] (Frontiers, 2021)
The high prevalence of allergy to β-lactam antibiotics is a worldwide issue. Accuracy of diagnostic methods is important to prove tolerance or allergy, with skin test considered the best validated in vivo method for ... -
Toward Two-Photon Absorbing Dyes with Unusually Potentiated Nonlinear Fluorescence Response
Benítez-Martín, Carlos; Li, Shiming; Dominguez-Alfaro, Antonio; Nájera-Albendín, Francisco; Perez-Inestrosa, Ezequiel; Pischel, Uve; Andréasson, Joakim[et al.] (American Chemical Society, 2020)
The combination of two two-photon-induced processes in a Förster resonance energy transfer (FRET)-operatedphotochromic fluorene-dithienylethene dyad lays the foundation for the observation of a quartic dependence of the ... -
Transition metal-free [2,3]-sigmatropic rearrangement in the reaction of sulfur ylides with allenoates
García-Castro, Miguel; Moya-Utrera, Federico; Sarabia-García, Francisco Ramón (RSC, 2023-08)
An unprecedented transition metal free [2,3]-sigmatropic rearrangement involving stabilized sulfur ylides and allenoates has been thoroughly established. The scope and utility of this reaction have been extensively studied ... -
Tripod-shaped molecules: Synthesis and immobilization on Au(1 1 1) substrates.
Sánchez-Molina, María; Díaz-Morilla, Amelia; Sauter, Eric; Zharnikov, Michael; López-Romero, Juan Manuel (2018-11-09)
We describe design and synthesis of novel tripod-shaped molecules that are potentially capable of monomolecular assembly on noble metal substrates, maintaining, due to their rigidity and specific geometry, the orientation ... -
Tripodal penta(p-phenylene) for the biofunctionalization of alkynyl-modified silicon surfaces.
Sánchez-Molina, María; Díaz-Morilla, Amelia; Valpuesta-Fernández, María; Contreras-Cáceres, Rafael; López-Romero, Juan Manuel; López-Ramírez, María Rosa[et al.] (Elsevier, 2018-03-22)
Here we report the optimization on the covalent grafting methodology of a tripod-shaped penta(p-phenylene), 1, on alkynyl-terminated silicon surfaces, and the incorporation of an active theophylline derivative, 2, for the ...