Listar QO - Artículos por autor "Nevado, Cristina"
Mostrando ítems 1-3 de 3
-
Dual Nickel/Photoredox-Catalyzed Asymmetric Carbosulfonylation of Alkenes
Du, Xiaoyong; Cheng-Sánchez, Iván; Nevado, Cristina (ACS, 2023-05-30)An asymmetric three-component carbosulfonylation of alkenes is presented here. The reaction, involving the simultaneous formation of a C–C and a C–S bond across the π-system, uses a dual nickel/photoredox catalytic system ... -
Hitting a Moving Target: Simulation and Crystallography Study of ATAD2 Bromodomain Blockers
Dolbois, Aymeric; Batiste, Laurent; Wiedmer, Lars; Dong, Jing; Brütsch, Manuela; Huang, Danzhi; Deerain, Nicholas M.; Spiliotopoulos, Dimitrios; Cheng-Sánchez, Iván; Laul, Eleen; Nevado, Cristina; Śledź, Paweł; Caflisch, Amedeo[et al.] (ACS Publications, 2020-06-30)Small molecule ligand binding to the ATAD2 bromodomain is investigated here through the synergistic combination of molecular dynamics and protein crystallography. A previously unexplored conformation of the binding pocket ... -
Nickel-Catalyzed Enantioselective Electrochemical Reductive Cross-Coupling of Aryl Aziridines with Alkenyl Bromides
Hu, Xia; Cheng-Sánchez, Iván; Cuesta-Galisteo, Sergio; Nevado, Cristina (ACS, 2023-03-07)An electrochemically driven nickel-catalyzed enantioselective reductive cross-coupling of aryl aziridines with alkenyl bromides has been developed, affording enantioenriched β-aryl homoallylic amines with excellent ...