Listar QO - Artículos por autor "Contreras-Cáceres, Rafael"
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Electrospun nanofibers: recent applications in drug delivery and cancer therapy
Contreras-Cáceres, Rafael; Cabeza, Laura; Perazzoli, Gloria; Díaz-Morilla, Amelia; López-Romero, Juan Manuel; Melguizo, Consolación; Prados, Jose[et al.] (MDPI, 2019-04)Polymeric nanofibers (NFs) have been extensively reported as a biocompatible scaffold to be specifically applied in several researching fields, including biomedical applications. The principal researching lines cover the ... -
Magnetically active pNIPAM nanosystems as temperature-sensitive biocompatible structures for controlled drug delivery
García-Pinel, Beatriz; Ortega Rodríguez, Alicia; Porras Alcalá, Cristina; Cabeza, Laura; Contreras-Cáceres, Rafael; Ortiz, Raúl; Díaz-Morilla, Amelia; Moscoso, Ana; Sarabia-García, Francisco Ramón; Prados, Jose; López-Romero, Juan Manuel; Melguizo, Consolación[et al.] (Taylor and Francis, 2020-04-19)Here, temperature-sensitive hybrid poly(N-isopropylacrylamide) (pNIPAM) nanosystems with magnetic response are synthesised and investigated for controlled release of 5-fluorouracil (5FU) and oxaliplatin (OXA). Initially, ... -
Nanoscale biocompatible structures generated from fluorinated tripodal phenylenes on gold nanoprisms
García-Castro, Miguel; Moscoso, Ana; Sarabia-García, Francisco Ramón; López-Romero, Juan Manuel; Contreras-Cáceres, Rafael; Díaz-Morilla, Amelia[et al.] (Wiley, 2022-03-09)Modification of gold substrates with a stable, uniform and ultrathin layer of biocompatible materials is of tremendous interest for the development of bio-devices. We present the fabrication of hybrid systems consisting ... -
SPION Nanoparticles for Delivery of Dopaminergic Isoquinoline and Benzazepine Derivatives.
Lucena-Serrano, Cristina; Lucena-Serrano, Ana; Díaz-Morilla, Amelia; Valpuesta-Fernández, María; Villaverde, Gonzalo; López-Romero, Juan Manuel; Sarabia-García, Francisco Ramón; Laurenti, Marco; Rubio Retama, Jorge; Contreras-Cáceres, Rafael[et al.] (Elsevier, 2022-06-27)Superparamagnetic iron nanoparticles (SPIONs) have become one of the most useful colloidal systems in nanomedicine. We report here the preparation of new hybrid core@shell systems based on SPION nanoparticles coated with ... -
Tripodal penta(p-phenylene) for the biofunctionalization of alkynyl-modified silicon surfaces.
Sánchez-Molina, María; Díaz-Morilla, Amelia; Valpuesta-Fernández, María; Contreras-Cáceres, Rafael; López-Romero, Juan Manuel; López-Ramírez, María Rosa[et al.] (Elsevier, 2018-03-22)Here we report the optimization on the covalent grafting methodology of a tripod-shaped penta(p-phenylene), 1, on alkynyl-terminated silicon surfaces, and the incorporation of an active theophylline derivative, 2, for the ...