Listar QO - Artículos por autor "Guerrero Vásquez, Guillermo A."

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An olefin cross-metathesis approach to depudecin and stereoisomeric analogues

Cheng-Sánchez, Iván; García-Ruiz, Cristina; Guerrero Vásquez, Guillermo A.; Sarabia-García, Francisco Ramón (ACS, 2017)

A new total synthesis of the natural product (−)-depudecin, a unique and unexplored histone deacetylase (HDAC) inhibitor, is reported. A key feature of the synthesis is the utilization of an olefin cross-metathesis strategy, ...
Synthesis and Antitumor Activity Evaluation of Compounds Based on Toluquinol

Cheng-Sánchez, Iván; Torres-Vargas, José Antonio; Martínez-Póveda, Beatriz Amparo; Guerrero Vásquez, Guillermo A.; Medina, Miguel Ángel; Sarabia-García, Francisco Ramón; Quesada, Ana R.[et al.] (MDPI, 2019-08-23)

Encouraged by the promising antitumoral, antiangiogenic, and antilymphangiogenic properties of toluquinol, a set of analogues of this natural product of marine origin was synthesized to explore and evaluate the effects of ...