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Listar MIC - Contribuciones a congresos científicos por autor "Alonso-Sánchez, María del Carmen"
Mostrando ítems 1-20 de 24
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Antiviral activity of European sea bass ISG15 against betanodavirus infections
Moreno, Patricia; García-Rosado, Esther; Borrego-García, Juan José; Alonso-Sánchez, María del Carmen (2017)To study the role of the sea bass ISG15 protein against betanodavirus infections, an in vivo transcription analysis has been performed after RGNNV infection and poly I:C inoculation, and the sea bass ISG15 activity has ... -
Characterization of Senegalese sole (Solea senegalensis) Mx promoter
Carballo Perez, Carlos; Alonso-Sánchez, María del Carmen; Collet, Bertrand; Béjar-Alvarado, Julia; Álvarez-Torres, Daniel; García-Rosado, Esther[et al.] (Elsevier, 2013)Type I interferon (IFN) represents a first component of the innate immune response against viral infections, promoting an antiviral state in cells. Mx proteins are the best studied IFN-inducible genes (ISGs) in fish. The ... -
Differences in the viral induction of the senegalese sole Mx protein in RTG-2 and CHSE-214 cells
Álvarez-Torres, Daniel; Podadera, Ana Maria; García-Rosado, Esther; Collet, Bertrand; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (EAFP, 2013)Transfected RTG-2 cells infected with VHSV showed significant induction of the luciferase reporter gene, compared to the control non-infected cells, at 24, 48 and 72 h post infection (p.i.). The maximum expression was ... -
Differential antiviral activity of Porphyridium cruentum polysaccharides against VHSV and NNV infections
Parra-Riofrio, Geovanna; Moreno-García, Patricia; Abdala-Díaz, Roberto Teófilo; García-Rosado, Esther; Uribe-Tapia, Eduardo; Alonso-Sánchez, María del Carmen; Béjar-Alvarado, Julia[et al.] (2021-09)The use of functional food can be an interesting approach to prevent viral diseases in aquaculture facilities. An increasing number of studies have suggested that marine microorganisms can be a relevant source of substances ... -
Estimulación del sistema mediado por interferón tipo I de lenguado senegalés (Solea senegalensis) en respuesta a infecciones por nodavirus
Podadera, AM; Álvarez-Torres, Daniel; Souto, S; Bandín Matos, Isabel; Alonso-Sánchez, María del Carmen (2014-09-25)El lenguado senegalés es susceptible a la infección por el Virus de la Necrosis Nerviosa Viral (VNNV). Los betanodavirus se clasifican en cuatro genotipos, siendo los genotiposSJNNV, RGNNV y virus recombinantes RGNNV-SJNNV ... -
Estudio in vitro de la actividad antagonista de aislados del virus de la septicemia hemorrágica viral (VHSV) de distinto origen sobre el sistema del IFN tipo I
Gémez-Mata, Juan; Álvarez-Torres, Daniel; Alonso-Sánchez, María del Carmen; García-Rosado, Esther; Béjar-Alvarado, Julia (2018-11-09)El lenguado senegalés (Solea senegalensis) es susceptible a aislados marinos del virus de la septicemia hemorrágica viral (VHSV); sin embargo, los VHSV patógenos para especies de agua dulce no son virulentos para especies ... -
Estudio in vitro de la actividad tipo citoquina de ISG15 de lubina frente a infecciones por Betanodavirus
Moreno-García, Patricia; Leiva-Rebollo, Rocío; García-Rosado, Esther; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen (2022-09)El sistema interferón tipo I (IFN-I) establece un estado antiviral mediante la transcripción de los llamados genes estimulados por IFN (ISG). Destaca el gen isg15, cuya proteína es la única descrita que presenta actividad ... -
European sea bass RTP3 genes: genomic characterization and transcription analyses.
Moreno-García, Patricia; Gémez-Mata, Juan; Álvarez-Torres, Daniel; García-Rosado, Esther; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (2023)Introduction: Fish RTP3, belonging to receptor-transporting protein (RTP) family, has been described as an interferon-α (IFN-α)-responsive gene. However, little information is available about fish rtp3 gene structure and ... -
Extractos del probiótico Shewanella putrefaciens Pdp11 protegen frente a la infección por RGNNV en cultivo celular
Moreno, Patricia; Balebona-Accino, María del Carmen; Moriñigo-Gutiérrez, Miguel Ángel; Alonso-Sánchez, María del Carmen; Béjar-Alvarado, Julia; García-Rosado, Esther[et al.] (2022)El agente etiológico de la retinopatía y encefalitis viral (VER) es el virus de la necrosis nerviosa (VNN). Aunque esta enfermedad puede causar una elevada mortalidad en numerosas especies de peces, no existen métodos ... -
In vitro viral coexistence decreases Striped Jack Nervous Necrosis Virus (SJNNV) but favours Red-spotted Grouper Nervous Necrosis Virus (RGNNV) replication
López-Jimena, Benjamín; Alonso-Sánchez, María del Carmen; Infante, Carlos; Castro-López, María Dolores; Borrego-García, Juan José; García-Rosado, Esther[et al.] (European Association of Fish Pathologists, 2013)In this study, several assays have been performed to characterise the effect of the RGNNV-SJNNV coexistence (coinfection and superinfection) on the replication of each genotype on E-11 cells.The results obtained showed the ... -
Infection of Artemia sp. by Lymphocystis disease virus (LCDV)
Jiménez Valverde, Estefanía; Cano, Irene; García-Rosado, Esther; Alonso-Sánchez, María del Carmen; Borrego-García, Juan José; Castro-López, María Dolores[et al.] (2013-12-10)In the present work, different developmental stages of Artemia sp. (metanauplius, juvenile and adult) were experimentally infected with LCDV by immersion. Results of viral quantification (both by qPCR and cell-culture viral ... -
Juvenile gilthead sea bream immune response against RGNNV or RGNNV/SJNNV infections
Gémez-Mata, Juan; Moreno Garcia, Patricia; Álvarez-Torres, Daniel; García-Rosado, Esther; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (Sociedad Española de Virología, 2024-09-02)Viral nervous necrosis is one of the main threats for the aquaculture. It is caused by the nervous necrosis virus (NNV), with a genome composed of two positive-sense, ssRNA segments: RNA1, encoding the viral polymerase; ... -
Papel del inmunogen isg15 de lubina (Dicentrarchus labrax) en las infecciones por betanodavirus
Moreno, Patricia; García-Rosado, Esther; Borrego-García, Juan José; Alonso-Sánchez, María del Carmen (Universidad de Oviedo, 2016)En peces, al igual que en vertebrados superiores, la respuesta antiviral innata está mediada por el sistema interferón tipo I (IFN I), que actúa mediante la activación de genes denominados isg (interferon-stimulated genes), ... -
Polisacáridos de Porphyridium cruentum presentan actividad antiviral diferencial frente a infecciones causadas de VHSV y VNN
Moreno Garcia, Patricia; Parra-Riofrio, Geovanna; Abdala-Díaz, Roberto Teófilo; García-Rosado, Esther; Uribe-Tapia, Eduardo; Alonso-Sánchez, María del Carmen; Béjar-Alvarado, Julia[et al.] (Sociedad Española de Microbiología, 2021)Los microorganismos del medio marino constituyen una importante fuente de compuestos cuya utilización en la prevención y/o tratamiento de enfermedades de etiología viral está siendo sugerida en los últimos años. En concreto, ... -
RRGNNV capsid protein amino acids 247 and 270 are involved in betanodavirus virulence to European sea bass (Dicentrarchus labrax)
Moreno, Patricia; Souto, Sandra; Leiva-Rebollo, Rocío; García-Rosado, Esther; Borrego-García, Juan José; Bandín Matos, Isabel; Alonso-Sánchez, María del Carmen[et al.] (2019-09-18)Recombinant RGNNV viruses harbouring SJNNV-type amino acids at positions 247 and/or 270 (Mut247Dl965, Mut270Dl965, Mut247+270Dl965) were generated by reverse genetics. The effect of these modifications on viral replication ... -
Senegalese sole (Solea senegalensis) ISG15: molecular characterization and in vivo interplay with viral infections
Álvarez-Torres, Daniel; Podadera, Ana María; Bandín Matos, Isabel; Béjar-Alvarado, Julia; García-Rosado, Esther; Alonso-Sánchez, María del Carmen[et al.] (2015-09-17)The interferon-stimulated gene 15 (Isg15) is strongly induced by type I interferon (IFN I), viral infection, and double-stranded RNA (poly I:C) in several fish species, suggesting that Isg15 protein could play a key role ... -
Senegalese sole transcriptomic profiles in response to different betanodavirus RGNNV/SJNNV reassortant strains
Labella Vera, Alejandro Manuel; Borrego-García, Juan José; Manchado, Manuel; Bandín Matos, Isabel; Castro-López, María Dolores; Alonso-Sánchez, María del Carmen; García-Rosado, Esther[et al.] (2017)Betanodaviruses are the causative agents of viral nervous necrosis (VNN), a disease that has been reported in more than 40 marine and freshwater fish species worldwide, including Senegalese sole (Solea senegalensis). Based ... -
Shewanella putrefaciens Pdp11 extracts promote European sea bass resistance against RGNNV infection.
Moreno-García, Patricia; Álvarez-Torres, Daniel; Gémez-Mata, Juan; Balebona-Accino, María del Carmen; Domínguez-Maqueda, Marta; Cerezo-Domínguez, Ana Isabel; Moriñigo-Gutiérrez, Miguel Ángel; Béjar-Alvarado, Julia; García-Rosado, Esther; Alonso-Sánchez, María del Carmen[et al.] (2024)The viral nervous necrosis (VNN) is a neurotropic disease affecting different fish species, resulting in high mortality rates. The causal agent is the nervous necrosis virus (NNV), belonging to the Betanodavirus genus, ... -
Shewanella putrefaciens Pdp11 extracts protect against betanodavirus infection.
Moreno-García, Patricia; Álvarez-Torres, Daniel; Balebona-Accino, María del Carmen; Moriñigo-Gutiérrez, Miguel Ángel; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen; García-Rosado, Esther[et al.] (2023)Viral nervous necrosis is caused by the nervous necrosis virus (Betanodavirus genus), a naked virus with two positive-sense RNA segments. Betanodaviruses are classified into four species, being RGNNV predominant in the ... -
El sistema del interferón tipo I protege a juveniles de lenguado senegalés (Solea senegalensis) frente a la infección por VHSV
Álvarez-Torres, Daniel; Podadera, AM; Vieytes, Lisandro P; Souto, S; Bandin, S; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen; García-Rosado, Esther[et al.] (2014-09-25)El lenguado senegalés (Solea senegalensis) es susceptible a la infección por el Virus de la Septicemia Hemorrágica Viral (VHSV) bajo condiciones experimentales. El objetivo de este trabajo es determinar el papel del sistema ...