ListarFHEFD - Contribuciones a congresos científicos por tema "Depression"
Mostrando ítems 1-20 de 21
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A Role For Galanin N-Terminal Fragment (1-15) In Anxiety And Depression in rats
(2015-10-06)Galanin (GAL) is involved in several functions including mood regulation. The GAL N-terminal fragment (1-15) [GAL(1-15)] also participates at central level and a differential role of GAL(1-15) compared with GAL has been ... -
Effects of galanin n-terminal fragment (1-15) in sac- charin self-administration and sucrose preference test in rats.
(2019-09-12)The Galanin N-terminal fragment (1-15) [GAL(1-15)] induces depressant- and anxiogenic- like actions in several behavioral tests, and these effects were significantly stronger than the ones induced by Galanin (1-29). Since, ... -
Effects of galanin n-terminal fragment (1-15) in the light/dark and tail suspension tests
(2015-10-21)Galanin N-terminal fragment (1-15) [Gal(1-15)] is involved in mood regulation. The intracerebroventricular (icv) administration of Gal(1-15) produces a depressive-like behaviour in the forced swim test (FST) and an ... -
Existence of FGFR1-5-HT1AR heteroreceptor complexes in hippocampal astrocytes. Putative link to 5-HT and FGF2 modulation of hippocampal gamma oscillations
(2021-11-04)The majority of the fibroblast growth factor receptor 1-serotonin 1 A receptor (FGFR1-5-HT1AR) heterocomplexes in the hippocampus appeared to be located mainly in the neuronal networks and a relevant target for antidepressant ... -
GAL(1-15) induces a depression and anxiogenic effect trough GALR1/GALR2 heteroreceptor: siRNA GALR1/GALR2 knockdown rats
(2015-10-06)The Galanin N-terminal fragment (1-15) [GAL(1-15)] induces depressant- and anxiogenic- like actions. In this work, we have studied the role of GALR2 and GALR1 on the effects of GAL(1-15) in the Forced Swimming Test (FST) ... -
Galanin (1-15) and escitalopram combination in rats reduces alcohol consumption in the ethanol self-administration test and improves escitalopram effects in the forced swimming test.
(2022-07-12)Recently, we described that Galanin(1-15)[GAL(1-15)] enhanced Escitalopram(ESC) effectiveness in depression symptoms. Moreover GAL(1-15) induces a substantial reduction in alcohol consumption. To investigate the effect of ... -
Galanin (1-15) enhances the behavioral effects of fluoxetine in the forced swimming test: a new therapeutic strategy against depression
(2017)The selective serotonergic (5- HT) reuptake inhibitors, including Fluoxetine (FLX), are the most commonly used for treatment of major depression. However, the understanding of the mechanism of action of FLX beyond its ... -
Galanin (1-15) enhances the effects of Fluoxetine in an animal model of depression. Role of the 5-HT1A receptor.
(2023)Major depression is one of the most significant contributors to global disability. Selective serotoninergicreuptake inhibitors, including Fluoxetine (FLX), are the most commonly used antidepressant but are onlyeffective ... -
Galanin and Neuropeptide Y Interaction Enhances Proliferation of Granule Precursor Cells and Expression of Neuroprotective Factors in the Rat Hippocampus: Role in depression and memory
(2022-09-22)Neuropeptide Y(NPY) Y1 receptor (Y1R) and galanin (GAL) receptor 2 (GALR2) interact in brain regions responsible for mood control and learning and memory processes, emphasizing the hippocampus. The current study assesses ... -
Galanin and Neuropeptide Y interaction leads to antidepressant effects through hippocampal cell proliferation.
(2020-09-01)Galanin (GAL) interacts with Neuropeptide Y Y1 receptors (NPYY1R) in several regions of the central nervous system associated with mood and motivation, through GAL receptor 2 and NPYY1 receptor 1 (GALR2/NPYY1R) heterodimers. ... -
Galanin and neuropeptide Y interactions linked to neuronal precursor cells of the dentate gyrus in the hippocampus. Role in depression and cognitive impairment.
(2021-11-05)Galanin (GAL) interacts with Neuropeptide Y Y1 receptors (NPYY1R) in several regions of the central nervous system associated with mood and motivation, through GAL receptor 2 and NPYY1 receptor 1 (GALR2/NPYY1R) heterodimers. ... -
Galanin interacts with Neuropeptide Y Y1 receptor in the dentate gyrus of the hippocampus through GALR2/NPYY1R heterodimers
(2016-07-11)We have shown Galanin(GAL) and Neuropeptide Y Y1(NPYY1) interactions at behavioural, cellular and receptor levels through GALR2/NPYY1R heterodimers in the amygdala. The aim of this work was to analyze GAL/NPYY1R interactions ... -
Galanin N-Terminal fragment (1-15) enhances the antidepressant effects of the 5-HT1A receptor agonist 8-OH-DPAT in the Forced Swimming Test.
(2016-07-27)Galanin and Galanin (1-15) [GAL(1-15)] are implicated in anxiety- and depression related behaviors. Moreover, Galanin modulates 5-HT1A receptor (5-HT1AR) function at autorreceptor and postsynaptic level in the brain. In ... -
Galanin N-Terminal fragment (1-15) induces a stronger effect than Galanin in depression- and anxiety- like related behavioural tests in rats.
(2014-07-16)Galanin (GAL) and GAL Receptors are implicated in anxiety- and depression- related behaviours. The GAL N-terminal fragment (1-15) [GAL(1-15)] also induces depressant- and anxiogenic- like actions. In this work, we have ... -
Galanin(1-15) reverses the impaired long-term memory effect of fluoxetine in the novel object recognition test. Role of 5-HT1A receptor in medial prefrontal cortex
(2019-12-16)In this work, we have studied the effects of GAL(1-15) on FLX- mediated effects on the NOR and the OLM, two tasks where FLX treatment impaired long-term memories 24h post-training. Since the mPFC is a core region for the ... -
GALR1/GALR2 Knockdown rats block the Depression and Anxiogenic effects induced by GAL(1-15): The Heterodimer GALR1/GALR2 as a target of GAL(1-15).
(2015-10-06)The Galanin N-terminal fragment (1-15) [GAL(1-15)] induces depressant- and anxiogenic- like actions. In this work, we have studied the role of GALR2 and GALR1 on the effects of GAL(1-15) in the Forced Swimming Test (FST) ... -
GALR2/NPYY1R heterodimers interact at receptor level in the dentate gyrus of the hippocampus in rats
(2016-09-26)Previously, we have described Galanin(GAL) and Neuropeptide Y Y1(NPYY1) interactions at behavioural, cellular and receptor levels through GALR2/NPYY1R heterodimers in the amygdala. The aim of this work was to study GAL/NPYY1R ... -
Improvement on hippocampal neuroproliferation through galanin and neuropeptide y y1 receptor agonist interaction
(2019-09-11)Neurogenesis persists in the hippocampus throughout the lifespan in a wide variety of species including humans. Within the dentate gyrus of the hippocampus, the subgranular zone (SGZ) is maintained as a stem cell niche. ... -
New augmentation strategy in depression: Galanin (1-15) enhances the behavioral effects of Fluoxetine in the olfactory bulbectomy rat.
(2022-07-12)Major depression is the largest contributor to global disability by years lived with disability. Selective serotonergic reuptake inhibitors, including fluoxetine (FLX), are the most commonly used antidepressant for the ... -
Role of the 5-HT1A receptors in the effect of Galanin(1-15) on Fluoxetine-mediated action in the forced swimming test
(2018-06-28)Galanin N-terminal fragment (1-15) [GAL(1-15)] modulates the antidepressant effects induced by the 5-HT1A receptor (5-HT1AR) agonist in the forced swimming test (FST) and the binding characteristics and mRNA levels of ...