Listar COG - Contribuciones a congresos científicos por tipo "info:eu-repo/semantics/conferenceObject"
Mostrando ítems 1-20 de 26
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Beneficial interactions between the microbiota and the host increase immunity for a better response to treatment of cancer patients
Burgos-Molina, Antonio Manuel
; González Vidal, Alejandro; Mercado-Sáenz, Silvia; Alamilla Presuel, Juan Carlos; Ruiz-Gómez, Miguel José (2022)
Numerous beneficial interactions between microbiota and host contribute to produce nutrients, metabolites, immunoglobulins and an increase in lymphocytes. The correct colonization of the intestine by microbiota induces a ... -
Cancer immunotherapy as a new treatment option
Burgos-Molina, Antonio Manuel; Padín-López, Alba; Alonso-Ortiz, Antonio (2019-01-16)
Cancer can coaptate the immune control of the immune system (IS), evade immunity and its destruction. So, could we say openly that immunotherapy is a viable treatment option for patients with advanced cancer? Yes, ... -
Case study of the intestinal microbiota using the XGN-MBI metagenomic assay
Burgos-Molina, Antonio Manuel; Mercado-Sáenz, Silvia; Gil-Carmona, Luisa; Morales-Moreno, Francisco; Ruiz-Gómez, Miguel José (2019-01-17)
The microbiota of the colon and rectum is the most abundant and diverse of the human body, with a density of up to 1-2 kg of weight and a diversity that exceeds a thousand species. Metagenomics can be defined as the ... -
Cellular microenvironment can be modulated by factors influenced by microbiota to improve cancer treatment
Burgos-Molina, Antonio Manuel; González Vidal, Alejandro; Mercado-Sáenz, Silvia; Alamilla Presuel, Juan Carlos; Ruiz-Gómez, Miguel José (2022)
Numerous environmental factors affect the ecosystem of the microbiota, so its composition and diversity can be modified by changes produced in these factors. These alterations can facilitate the appearance of pathological ... -
Construction techniques and architectural design to reduce the level of radon inside buildings and therefore the risk of cancer
Burgos-Molina, Antonio Manuel; Ruiz-González, Óscar M.; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (2022)
The incorporation of anti-radon membranes and forced ventilation and depressurization systems in buildings contributes to reduce the concentration of radon inside rooms. In this way, the exposure to radiation in its ... -
Exposure of cancer cells to heat shock protein inhibitors induces decreased tumour survival
Burgos-Molina, Antonio Manuel; Peinado-Ruiz, Isabel C.; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (2022)
All tumour studied show an increase in resistance to treatment and an increase in cell survival. This response is related to an increase in the heat shock protein HSP90, since it participates in the assembly of telomerase, ... -
Fears and catastrophic thoughts in medically complicated pregnancies
González-Mesa, Ernesto Santiago (2019-10-23)
In our experience "High-risk" diagnosis stigmatizes the patient, compromises her self-esteem, fears come up, and often modifies her expectations of a successful pregnancy in a catastrophizing, unrealistic way. Thinking ... -
Heat shock proteins overexpressed in tumour cells and their relationship with ageing and cellular resistance to treatment
Burgos-Molina, Antonio Manuel; Peinado-Ruiz, Isabel C.; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (2022)
The increase in the concentration of HSP in tumour cells produces an increase in the capacity for replication, migration, and drug resistance. HSP and HSF1 factor are involved in the etiology of breast cancer. The ... -
Increased resistance to drugs and longer life cycle by the administration of exogenous agents to normal human cells
Burgos-Molina, Antonio Manuel; Peinado-Ruiz, Isabel C.; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (2022)
Exogenous HSP70 provides protection against oxidative stress and that it could be a good therapeutic strategy to treat age-related macular degeneration. On the other hand, externally inoculating a heat shock protein to ... -
Intestinal microbiota and colorectal cancer
Burgos-Molina, Antonio Manuel; Mercado-Sáenz, Silvia; Morales-Moreno, Francisco; Gil-Carmona, Luisa; Ruiz-Gómez, Miguel José (2019-01-16)
Colorectal cancer may be influenced by changes in the intestinal microbiota that affect the mucosa and cause an immune response capable of producing inflammatory effects. Although there are still few studies in this regard, ... -
Mechanisms of cross resistance between cisplatin and bleomycin in saccharomyces cerevisiae
Tumor cells can simultaneously acquire resistance against a diverse group of drugs. This phenomenon is called pleotropic resistance or multidrug resistance. This mechanism could explain the tumor resistance observed in ... -
Methods to study the intestinal microbiota to address the disease in a more precise and personalized way
Burgos-Molina, Antonio Manuel; González Vidal, Alejandro; Mercado-Sáenz, Silvia; Alamilla Presuel, Juan Carlos; Ruiz-Gómez, Miguel José (2022)
FISH, clone collection, DGGE, PCR and metagenomics techniques contribute to the study of the human microbiota in a precise and effective way, constituting very useful diagnostic tools in precision medicine to address patient ... -
Microbiota and body axes as a new therapeutic approach in precision medicine
Burgos-Molina, Antonio Manuel; González Vidal, Alejandro; Alamilla Presuel, Juan Carlos; Mercado-Sáenz, Silvia; Ruiz-Gómez, Miguel José (2022)
There is a marked relationship between the composition and diversity of the microbiota and various diseases distant from the intestine. This relationship occurs through different body axes between the intestine and the ... -
New markers of bleomycin resistance
Resistance to chemotherapy is one of the main problems of this type of therapy. Studies carried out determine the usefulness of predictive biomarkers to improve this treatment. The aim of this work is to carry out a ... -
One hundred of cells generations connect the resistance to drugs and the replicative aging mechanisms
There are researchs that reveal a relationship between acquired resistance to antineoplastic drugs and aging. Therefore, the identification of genes involved in senescence could have a potential therapeutic utility for ... -
Presence of radon pollution in buildings and risk of cancer
Burgos-Molina, Antonio Manuel; Ruiz González, Óscar M.; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (2022)
Radon gas present in the ground penetrates into homes through different routes, accumulating especially in rooms close to the ground. The dose received from radioactivity due to inhalation of radon inside houses poses a ... -
Proteomic analysis in wild type and cisplatin resistant yeast strain of saccharomyces cerevisiae
Research carried out in oncology has allowed the identification and characterization of molecular markers of resistance to antineoplastic drugs. It supposes a great advance and allows the administration of customized ... -
Real-time PCR optimization to identify Mycobacterium tuberculosis complex strains in clinical samples.
During recent years several molecular techniques have become available for Mycobacterium tuberculosis complex (MTC) detection,both for clinical samples and for isolates. One of the techniques more widely used is real time ... -
Relationship between chronological aging and acquired resistance to cisplatin in the yeast saccharomyces cerevisiae
Burgos-Molina, Antonio Manuel; Mercado-Sáenz, Silvia; Gil-Carmona, Luisa; Ruiz-Gómez, Miguel José (2019-01-17)
The Sir2 gene is associated with an increase in longevity in yeasts, worms, flies and rodents. The human homolog, Sirt1, is also involved in longevity, by inhibiting cellular senescence. Studies carry out in tumor cells ... -
Resistance acquisition after seven cycles of in vitro bleomycin exposure
Burgos-Molina, Antonio Manuel; Gil-Carmona, Luisa; Lumbreras-Vega, Luis Joaquín; Ruiz-Gómez, Miguel José (2019-01-16)
Bleomycin is an antineoplastic drug that causes DNA damage by intra- and inter-strand crosslink and DNA strand breaks. This drug is used to treat several types of cancer. The aim of this work is to study the effect of ...