BMB - Contribuciones a congresos científicos: Envíos recientes
Mostrando ítems 21-40 de 248
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Rising to the Challenge: Developing Biosensors to Study Nitrogen Transport in Plants
Nitrogen (N) plays a crucial role in plant development and growth, which is why high concentrations of N in the form of fertilizers are commonly used in agricultural crops. However, the excess N present in fertilizers is ... -
Antiangiogenic potential of an anthraquinone metabolite isolated from a marine fungus.
Vidal-Valenzuela, Isabel; Torres-Vargas, José Antonio; García-Caballero, Melissa; Medina-Torres, Miguel Ángel
; Rodríguez-Quesada, Ana María (2023)
The potential of marine organisms to yield bioactive molecules is vast and largely unexplored. Significantly, certain bioactive compounds derived from the marine environment have already received approval as anticancer ... -
Peripheral membrane TTL proteins safeguard cellulose synthesis under stress.
Amorim-Silva, Vitor; García-Moreno, Álvaro; Kesten, Christopher; Menna, Alexandra; Castillo-Garriga, Araceli; Percio-Vargas, Francisco; Pagano Márquez, Raquel; Moya-Cuevas, José; Armengot, Laia; Ruiz-López, Noemí; Jallais, Yvon; Sánchez-Rodríguez, Clara; Botella-Mesa, Miguel Ángel[et al.] (2023)
Land plants provide around eighty percent of biomass on Earth and roughly one-third corresponds to cellulose (Bar-On et al 2018). Despite its biological and societal importance, many aspects of cellulose biosynthesis and ... -
Pining for answers: Study of cationic amino acids (CATs) transport in maritime pine Pinus pinaster Aiton.
Medina Morales, Beatriz; Ávila-Sáez, Concepción; Cánovas-Ramos, Francisco Miguel; Castro-Rodríguez, Vanessa Viviana (2023)
Amino acid (AA) transporters are membrane proteins involved in AA mobilization within and between cells and cells compartments. In plants, these transporters are responsible of AA transport from sink to source organelle/cell ... -
Phosphorylation regulates cellulose biosynthesis regulation.
Percio-Vargas, Francisco; Toth, Ryan; DeFalco, Thomas A.; Persson, Staffan; Zipfel, Cyril; Amorim-Silva, Vitor; Botella-Mesa, Miguel Ángel[et al.] (2023)
Plants comprise over 82% of all biomass on Earth, a third of which is cellulose, making it the most abundant organic compound¹. Cellulose is also essential for plant development and defense against multiple stresses. ... -
Under pressure: Abies pinsapo Boiss, queen of the response to high temperature and water stress.
Blanca Reyes, Irene Victoria; Ávila-Sáez, Concepción; Cánovas-Ramos, Francisco Miguel; Castro-Rodríguez, Vanessa Viviana (2023)
The Spanish fir (Abies pinsapo Boiss) is an ecologically and economically important conifer species, but little is known about its molecular responses to abiotic stresses related to climate change. The study of molecular ... -
Selected problems/cases to stimulate collaborative learning regarding the dynamic flexibility of metabolism.
Metabolic reprogramming has been identified as one of the hallmarks of cancer. Furthermore, it is becoming more and more frequent to establish connection between other diseases and metabolic rewiring. One of us has recently ... -
The Extra Virgin Olive Oil phenolic compounds () oleacein and () oleocanthal inhibit tumor cell autophagy
Marrero Capitán, Ana Dácil; Posligua-García, Joel; Bernal, Manuel; Ortega Vidal, Juan; Salido, Sofía; Altarejos, Joaquín; Rodríguez-Quesada, Ana María; Martínez-Póveda, Beatriz Amparo; Medina-Torres, Miguel Ángel[et al.] (2023)
Our group has recently shown that the antitumor Extra Virgin Olive Oil phenolic compounds (—)oleocanthal and (—)oleacein also behave as antiangiogenic agents. Interestingly, it has been described that phenolic compounds ... -
Three component-based bi-layer and ecofriendly mulching films.
Sanchez, Laura Mabel; Benitez, José Jesús; Domínguez Carmona, Eva María; Heredia-Bayona, Antonio (2023)
Among the agronomic practices usually employed to achieve more successful culture results, mulching (M) has been applied using a variety of materials. In particular, the employment of plastic M films has made a revolution ... -
Deciphering the role of specialized ribosomes in plants´ translation efficiency
(2023)Translation and its regulation play an important role in plant adaptation. Ribosomes have traditionally been considered passive molecular players regarding which RNA to translate. However, this view is changing due to ... -
Translation dynamics of the plant-virus interaction
Sans-Coll, Gemma; Castillo-Garriga, Araceli; Rodríguez-Bejarano, Eduardo; Merchante-Berg, Catharina (2023)
Tomato yellow leaf curl virus (TYLCV) causes a disease that gives rise to massive damage to tomato crops world-wide (Prasad et al., 2020). As a virus, it requires the host’s cellular machinery to be able to infect, which ... -
The role of DGK1 and DGK2 in Membrane Contact Sites and Stress Tolerance
García Hernández, Selene; Ruiz-López, Noemí; Botella-Mesa, Miguel Ángel (2023-06-05)
All eukaryotic cells present regions where the membranes of two different organelles are very close (10-30 nm) without fusion, mediated by tether proteins. These regions are known as Membrane Contact Sites (MCS). Contact ... -
Functional characterization of Arabidopsis thaliana Synaptotagmin1 domains using Tricalbin3 chimeras in Saccharomyces cerevisiae
Benítez-Fuente, Francisco; Amorim-Silva, Vitor; Collado, Javier; Fernández-Busnadiego, Rubén; Botella-Mesa, Miguel Ángel (2023-06)
Synaptotagmin1 (SYT1) is an Arabidopsis thaliana endoplasmic reticulum (ER)-plasma membrane contact site tether involved in biotic and abiotic stress resistance. These resistance roles have been related to SYT1 tethering ... -
Antioxidant potential of an anthraquinone metabolite isolated from a marine fungus.
Vidal-Valenzuela, Isabel; Torres-Vargas, José Antonio; García-Caballero, Melissa; Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María (2023)
Marine ecosystem is a fruitful source of many pharmacologically active. In particular, a number of marine anthraquinones and their derivatives, have been studied for their potential as anticancer and antimetastatic agents, ... -
Translational regulation of hormone synthesis and signaling mRNAs
(2023)Translational regulation has long been recognized as a vital process in the cell responses to the environment and in the execution of developmental programs, yet still little is known about the selective translation of ... -
(-)-Oleacein and (-)-oleocanthal, two phenolic compounds present in Extra Virgin Olive Oil, inhibit angiogenesis
Ortega Vidal, Juan; Salido, Sofía; Altarejos, Joaquín; Marrero Capitán, Ana Dácil; Rodríguez-Quesada, Ana María; Martínez-Póveda, Beatriz Amparo; Medina-Torres, Miguel Ángel[et al.] (2022-11)
Phenolic compounds in the Mediterranean diet contribute to many of the health-related benefits accounted in this dietary choice. (-)-Oleocanthal and the less studied (-)-oleacein, are two phenolic compounds present in the ... -
The immunomodulator dimethyl taconite inhibits several key steps of angiogenesis in cultured endothelial cells
Vidal-Valenzuela, Isabel; Fernández-Florido, Elena; Marrero Capitán, Ana Dácil; Castilla, Laura; Rodríguez-Quesada, Ana María; Martínez-Póveda, Beatriz Amparo; Medina-Torres, Miguel Ángel[et al.] (2022)
Dimethyl itaconate (DMI) is a cell-permeable derivative of itaconate, a known immunomodulator metabolite synthesized from the Krebs cycle intermediate cis-aconitate by the enzyme aconitate dehydrogenase. Although DMI is ... -
Antitumor activity of Toluquinol
Torres-Vargas, José Antonio; Sounni, Nor Eddine; Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María; García-Caballero, Melissa (2022)
Colorectal cancer (CRC) is the third most common cause of cancer mortality worldwide, with more than 1.85 million cases and 850.000 deaths annually1. Currently, the primary methods for treating CRC are surgery, radiotherapy ... -
Metabolic impact of glutaminase isoenzymes modulation on glioma cell lines
De los Santos-Jiménez, Juan; Rosales, Tracy; Bookyung, Ko; Márquez-Gómez, Javier; DeBerardinis, Ralph J; Mates-Sánchez, José Manuel[et al.] (2022)
Many tumors use glutamine for both energy generation and as a biosynthetic precursor. Glutaminases (GAs) catalyze the first step of glutaminolysis by converting glutamine (Gln) into glutamate and ammonia in the mitochondria. ... -
Bioinformatic analyses of olive pollen tube and seed transcriptomes and their integration in an interactive olive expression atlas
Bullones, Amanda; Fernández-Pozo, Noé; Lima-Cabello, Elena; Castro, Antonio Jesús; Alché-Ramírez, Juan de Dios; Claros-Díaz, Manuel Gonzalo[et al.] (2022)
The olive tree (Olea europaea L.) is of great socioeconomic importance due to the production of oil and table olives, and the seed is also an emergent source of nutraceuticals (Jiménez-Ruiz et al., 2020) and feed supplements ...