ListarBCGF - Contribuciones a congresos científicos por tema "Hydrocephalus"
Mostrando ítems 1-13 de 13
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A sequential cell therapy to recover the ependymal cells in posthemorrhagic hydrocephalus.
(2022-09)Background Germinal matrix haemorrhages and intraventricular haemorrhages (GMH/IVH) lead to posthemorrhagic hydrocephalus (PHH), a relevant cause of morbidity and mortality in the premature neonatal population. The ... -
Bone marrow-derived mesenchymal stem cells transplantation produces a tissue recovery in hydrocephalic mice
(2018-07-25)In congenital hydrocephalus, cerebrospinal fluid accumulation is associated to ischemia/hypoxia, metabolic impairment, neuronal damage and astrocytic reaction, which cause significant mortality and life-long neurological ... -
Brain tissue recovery in obstructive congenital hydrocephalus after intraventricular transplantation of mesenchymal stem cells
(2018-10-29)Introduction: Bone marrow-derived mesenchymal stem cells (BM-MSC) are a potential therapeutic tool due to their ability for migrating and producing neuroprotector factors when transplanted. The aim of this study was to ... -
Characterization and administration of bone marrow-derived mesenchymal stem cells in an animal model of congenital hydrocephalus
(2015-07-08)Bone marrow-derived mesenchymal stem cells (BM-MSC) are considered as a potential therapeutic tool in neurodegenerative diseases, due to their ability to migrate to degenerated tissues and the production of growth factors. ... -
Human Mesenchymal Stem Cells and its Exosomes in Posthemorrhagic Hydrocephalus: A Focus on Edema and Ependymal Repair
(SRHSB 2024 Annual Conference, 2023-09-04)Background Germinal matrix hemorrhages and intraventricular hemorrhages (GMH/IVH) often lead to posthemorrhagic hydrocephalus (PHH), a severe cause of morbidity and mortality in premature neonates. GMH/IVH is known to ... -
IPSC differentiation into ependymal progenitors to treat ventricular damage during hydrocephalus
(2018-10-30)Introduction: During both obstructive congenital hydrocephalus and post-hemorrhagic hydrocephalus additional pathological events are intimately associated with their ethiology: a) a detrimental inflammatory response; b) ... -
iPSC differentiation into ependymal progenitors to treat ventricular damage during hydrocephalus
(2019-07-03)Introduction: During both obstructive congenital hydrocephalus and post-hemorrhagic hydrocephalus additional pathological events are intimately associated with their ethiology: a) a detrimental inflammatory response; b) ... -
Metabolite fingerprint detected with HR-MAS spectroscopy in ex vivo samples of cases with congenital hydrocephalus
(2014-07-16)Background: Changes in the profile of metabolites in brain and/or fluids can be useful to evaluate the severity and evolution of hydrocephalus, and consequently to help in treatment decisions. Magnetic Resonance Spectroscopy ... -
A metabolite profile reveals the presence of neurodegenerative conditions according to severity of hydrocephalus
(2018-11-29)Introduction: In obstructive congenital hydrocephalus, cerebrospinal fluid accumulation is associated with high intracranial pressure (ICP), ischemia/hypoxia, metabolic impairment, neuronal damage and astrocytic reaction. ... -
Multiciliated ependyma recovery through a sequential cell therapy in posthemorrhagic hydrocephalus.
(2023)Posthemorrhagic hydrocephalus (PHH) is a significant cause for premature children’s morbidity, mortality, and peri/postnatal neurodevelopmental impairment. PHH is mainly triggered by germinal matrix hemorrhages (GMH) and ... -
Potential protective role of reactive astrocytes in the periventricular parenchyma in congenital hydrocephalus
(2016-07-11)Background Cerebrospinal fluid accumulation in hydrocephalus produces an elevation of intraventricular pressure with pathological consequences on the periventricular brain parenchyma including ischemia, oedema, oxidative ... -
Testing exosomes as a treatment for posthemorrhagic hydrocephalus.
(2023)Germinal matrix hemorrhages and intraventricular hemorrhages (GMH/IVH) lead to posthemorrhagic hydrocephalus (PHH), a severe cause of morbidity and mortality in premature neonates. GMH/IVH disrupts the ependyma, which forms ... -
The ependymal detach due to neuraminidase provokes hydrocephalus
(2015-05-27)Background: In many cases there seems to exist a tight relationship between the integrity of the ependymal barrier and the onset of hydrocephalus (see 1). We wanted to investigate this by means of a repetitive model that ...