ListarBCGF - Contribuciones a congresos científicos por tema "Astrocitos"
Mostrando ítems 1-3 de 3
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Human pluripotent stem cell-derived astrocytes from alzheimer´s disease patients for disease modeling
(2022)Aims: The lack of reliable models of Alzheimer´s disease (AD) has impeded the development of effective therapies. Glial cells have a key role in AD pathology, but this cannot be properly modeled using available animal ... -
Mitochondrial ultrastructural defects in reactive astrocytes of Alzheimer's mice hippocampus.
(2023)Alzheimer's disease (AD) is a complex neurodegenerative condition that causes progressive memory loss and dementia. In AD brains astrocyte become reactive potentially contributing to cognitive decline. Astrocyte reactivity ... -
Ultrastructural evidence of mitochondrial pathology in hippocampal reactive astrocytes of β-amyloidosis Alzheimer’s transgenic mice
(Cold Spring Harbor Laboratory, 2022)Astrocytes, the most abundant non-neuronal cell type in the CNS, play essential roles in brain homeostasis and neuroprotection, including metabolic support, synaptic plasticity, cerebral blood flow and immunity. Many of ...