Listar BCGF - Contribuciones a congresos científicos por fecha de publicación
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Antiviral activity of mx proteins from gilthead seabream (sparus aurata) against lymphocystis disease virus (LCDV).
(ELSEVIER, 2013)Gilthead seabream (Sparus aurata), one of the most important fish species in the Mediterranean Aquaculture displays a high natural resistance to viral diseases. Until now, the main viral disease affecting gilthead seabream ... -
Dopamine D4 receptor activation counteracts nigrostriatal pathway activation by morphine: relevance in drug addiction.
(2013)Morphine induces dopamine release in the caudate putamen (CPu), which promotes stereotyped behavior and habit learning for drug-seeking and –taking. Nigrostriatal pathway stimulation by morphine is due to a removal of tonic ... -
Litio como terapia neuroprotectora en el modelo APPSL/PS1M146L de la enfermedad de Alzheimer.
(2013)El litio se utiliza desde hace varias décadas en el tratamiento de trastornos bipolares y la depresión, y recientemente se debate su uso potencial en patologías neurodegenerativas como la enfermedad de Alzheimer (AD). ... -
Infectivity decline of an RNA plant virus by increased mutagenesis supports the lethal defection model in vivo
(2013-07-30)Lethal mutagenesis is a new antiviral therapy based on increasing the mutation rate by using mutagenic base and nucleoside analogues whose molecular mechanisms are not fully understood. Most of the research has been conducted ... -
Thymine starvation causes abortive initiation of chromosome replication critical for cell death in Escherichia coli
(SEBBM, 2013-09-04)Thymineless death (TLD), a phenomenon in which thymine auxotrophy becomes lethal when cells are starved for thymine, can be prevented by rifampicin addition. In this work, we have obtained evidence indicating that among ... -
Las dos proteínas Mx de lubina (Dicentrarchus labrax) responden de forma diferente a la infección por VNNV
(2013-10-01)Las proteínas Mx son elementos clave en el estado antiviral desencadenado por el interferón tipo I en respuesta a las infecciones virales. En este trabajo se han identificado dos genes Mx en lubina (Dicentrarchus labrax), ... -
Polimorfismos en la MxB de lubina (Dicentrarchus labrax) y susceptibilidad a VNNV
(2013-10-01)La resistencia a las enfermedades es uno de los caracteres más interesantes en los programas de mejora genética en acuicultura. Las proteínas Mx son elementos clave en el estado antiviral desencadenado por el interferón ... -
Bone marrow mesenchymal stem cells, collagen scaffold and BMP-2 for rat spinal fusio
(2013-11-08)The use of autograft for posterolateral spinal fusion, continue being considered the gold standard for the treatment of spine pathologies. However, due to complications such as donor site morbidity, increased operating ... -
Combining tissue engineering with metal scaffolds in orthopaedic to improve osseointegration of endoprothesis
(2013-11-08)Electron Beam Melting (EBM) technology allows the fabrication of free-formed metal scaffolds, thus creating the possibility of manufacturing patient-specific endo-prostheses. It also allows the production of highly-porous ... -
A synthetic collagen-binding arg-gly-asp (rgd) biomimetic peptide enhances bone cell differentiation
(2013-11-27)RGD (arginine-glycine-aspartic acid) peptides have shown some promising abilities to promote the attachment of cells to biomaterials and to direct their differentiation. However, anchoring these peptides to the biomaterial’s ... -
Synergism analysis between the pathogen infection and abiotic stresses
(2013-12-10)Genetic and biochemical dissection of signaling pathways regulating plant pathogen defense has revealed in the last years remarkable similarities to the response to some abiotic streses. However very little is known about ... -
Interaction of geminiviruses with the ubiquitination pathway
(2013-12-10)Geminiviruses rely heavily on the host cellular machinery and interact with a wide range of plant proteins and processes during infection. They change host gene expression patterns, inhibit cell death pathways, and interfere ... -
A sensitive method to quantify replicative forms of circular DNA viruses
(2013-12-13)Although real-time PCR diagnostic protocols for detection of geminivirusesare available, none of them are able to discriminate between the two strands generated during an infection: the viral strand (VS) that is encapsidated ... -
Molecular Ecology of Geminivirus C2 protein over the viral insect vector Bemisia tabaci
(2013-12-13)Plant-pathogen-vector systems are characterized by a complex array of direct and indirect interactions, usually not well understood. The whitefly Bemisia tabaci is responsible for extensive losses mainly through the ... -
Geminivirus Rep Protein Interferes with the Plant DNA Methylation Machinery and Suppresses Transcriptional Gene Silencing
(2013-12-13)Cytosine methylation is an epigenetic mark that promotes gene silencing and plays an important role in genome defense against transposons and invading DNA viruses. So far just one geminiviral protein, C2 from Tomato golden ... -
Neural stem cell signaling by dysregulation leading to cancer
(2013-12-17)Notch signaling regulates proliferation, differentiation and survival of neural stem cells (NSCs) in the central nervous system. Transformed NSCs are thought to be the origin of brain cancer stem cells and of the more ... -
Transcripcional, functional and virulence analysis of a Pseudomonas Savastanoi pv. savastanoi genomic region shared with other pathogens of woody hosts
(2014-06-09)The genome of the olive tree pathogen Pseudomonas savastanoi pv. savastanoi (Psv) NCPPB3335 (58.1% G+C) encodes a region of about 15 kb, named VR8 (60.4% G+C), which is absent in all sequenced Pseudomonas syringae strains ... -
Lithium, as a neuroprotective therapy for Alzheimer’s disease pathology, modifies abeta plaque toxicity
(2014-07-02)BACKGROUND: Despite the relatively large information about the Alzheimer’s disease (AD) pathology, no effective disease-modifying treatment has been yet developed. Lithium, a primary drug to treat bipolar disorder, has ... -
A model of neuroinflammation and demyelination by intracerebroventricular injection of microbial neuraminidase
(2014-07-14)Neuraminidase from Clostridium perfringens, which cleaves terminal sialic acid from carbohydrate chains, was injected in the lateral ventricle of rats. It diffused in the ipsilateral ventricle, the third ventricle, and ... -
Metabolite fingerprint detected with HR-MAS spectroscopy in ex vivo samples of cases with congenital hydrocephalus
(2014-07-16)Background: Changes in the profile of metabolites in brain and/or fluids can be useful to evaluate the severity and evolution of hydrocephalus, and consequently to help in treatment decisions. Magnetic Resonance Spectroscopy ...