Listar BCGF - Contribuciones a congresos científicos por título
Mostrando ítems 231-250 de 265
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Systemic administration of epothylone-d recues memory and ameliorates Alzheimer’s disease-like pathology in APP/PS1 mice.
(2017-04-17)Aims Cognitive and memory decline in Alzheimer's disease (AD) patients is highly related to synaptic dysfunction and neuronal loss. Tau hyperphosphorylation destabilizes microtubules leading to axonal transport failure, ... -
Tau pathology and astroglial reactivity: a comparative study of two mouse models of tauopathy
(2022)Objectives: Astrocytes are becoming crucial players in the context of neurodegenerative proteinopathies, such as Alzheimer’s disease (AD). Astroglial response has been mainly analyzed in amyloidogenic scenarios, but less ... -
Tenocytic induction of stem cells from bone marrow on polymeric microparticles for a new concept of tendon regenerative prosthesis
(2015-10-26)A new concept of a regenerative and resorbable prosthesis for tendon and ligament has been developed. The prosthesis consists of a poly-lactide acid (PLA) braid, microparticles in its interior serving as cell carriers, and ... -
Testing exosomes as a treatment for posthemorrhagic hydrocephalus.
(2023)Germinal matrix hemorrhages and intraventricular hemorrhages (GMH/IVH) lead to posthemorrhagic hydrocephalus (PHH), a severe cause of morbidity and mortality in premature neonates. GMH/IVH disrupts the ependyma, which forms ... -
The bacterial effector HopAF1 interacts with Arabidopsis MKK4/5
(2022-06)Pseudomonas syringae is a phytopathogenic bacterium whose virulence depends on a Type III Secretion System and its effector (T3E) repertoire, which is translocated into the host cell cytosol suppressing both basal and ... -
The begomovirus Tomato leaf curl New Delhi virus is not seed-transmitted in melon
(2022-09)Transmission of plant viruses through seed can be one of the major factors contributing to long- distance dispersal through global trade of seeds and can have important ecological consequences for virus dissemination. ... -
The begomovirus tomato leaf curl New Delhi virus is not seed-transmitted in melon
(2022)Transmission of plant viruses through seed can be one of the major factors contributing to longdistance dispersal through global trade of seeds and can have important ecological consequences for virus dissemination. ... -
The effect of combining bone morphogenetic proteins -2 and -6 on osteoblastic differentiation and bone
(2015-07-21)Bone morphogenetic proteins-2 and -7 (BMP-2 and -7) are the only two members of the BMP subfamily approved to date to be used in combination with collagen type I in orthopedic surgery, although other BMPs have proven to ... -
The effect of different amyloid seeds and animal hosts on amyloid propagation in Alzheimer's Disease
(2022-07-13)Abstract text: Alzheimer's Disease is a neurodegenerative proteinopathy in which recent evidence indicates that Aβ can misfold and aggregate into seeds that structurally corrupt native proteins, mimicking a prion-like ... -
The ependymal detach due to neuraminidase provokes hydrocephalus
(2015-05-27)Background: In many cases there seems to exist a tight relationship between the integrity of the ependymal barrier and the onset of hydrocephalus (see 1). We wanted to investigate this by means of a repetitive model that ... -
The iaaL gene in the Pseudomonas syringae complex: functional characterization and biological activity
(2022-07-08)Phytopathogenic bacteria of the Pseudomonas syringae complex are causal agents of diseases in a wide variety of woody and herbaceous plants with agronomic and ornamental interest. Indole-3-acetic acid (IAA) is an auxin ... -
The Skeletal Atlas: A holistic approach to transcriptomics in the skeleton.
(2023)Gene expression atlases are powerful bioinformatics tools that allow access to the scientific community to explore omics data. In biomedicine, numerous gene expression databases are available, yet none provide enough ... -
The transcriptional regulator JAZ8 interacts with the C2 protein from geminiviruses and limits the geminiviral infection in Arabidopsis
(2023)Jasmonates (JAs) are phytohormones that finely regulate critical biological processes, including plant development and defense. JASMONATE ZIM-DOMAIN (JAZ) proteins are crucial transcriptional regulators that keep JA-responsive ... -
The When and Where: How development modulates immunity through a miRNA-NLR-phasiRNA network
(2022)Plants possess a battery of dedicated intracellular immune receptors known as nucleotide-binding leucine-rich repeat proteins (NLRs) involved in recognition of pathogen-derived effectors and activation of effector-triggered ... -
THESEUS1 and RALF34 monitor cell wall integrity
(2022-09-14)The cell wall is a rigid network being the first barrier between a plant cell and its environment, but at the same time has to be a dynamic network whose cell growth and shape is given by deposition and remodeling of the ... -
Thymine starvation causes abortive initiation of chromosome replication critical for cell death in Escherichia coli
(SEBBM, 2013-09-04)Thymineless death (TLD), a phenomenon in which thymine auxotrophy becomes lethal when cells are starved for thymine, can be prevented by rifampicin addition. In this work, we have obtained evidence indicating that among ... -
Transcripcional, functional and virulence analysis of a Pseudomonas Savastanoi pv. savastanoi genomic region shared with other pathogens of woody hosts
(2014-06-09)The genome of the olive tree pathogen Pseudomonas savastanoi pv. savastanoi (Psv) NCPPB3335 (58.1% G+C) encodes a region of about 15 kb, named VR8 (60.4% G+C), which is absent in all sequenced Pseudomonas syringae strains ... -
Transcriptional profile and serological studies of the European sea bass immune response against betanodavirus infections
(2019-07-19)European sea bass is highly affected by outbreaks of viral nervous necrosis disease, provoked by the nervous necrosis virus (NNV). This virus displays a positive-sense RNA genome composed of two segments, RNA1, encoding ... -
Transcriptomic analysis of the interaction geminivirus-tomato
(2019-06-07)Geminiviridae family is one of the main families of plant pathogenic viruses with large relevance as they cause great losses worldwide in commercial crops and crops destined to food production. Geminiviruses present a ... -
Type III secretion system effectors and host specificity in Pseudomonas savastanoi pathovars of woody hosts
(2021-09)The species Pseudomonas savastanoi, a member of the Pseudomonas syringae complex, includes five pathovars causing knots or excrescences in woody hosts: P. savastanoi pv. savastanoi, pv. fraxini, pv. nerii, pv. retacarpa ...