Listar BCGF - Contribuciones a congresos científicos por título
Mostrando ítems 62-81 de 265
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D-chiro-inositol prevents memory deficits in the 3xTg mouse model of Alzheimer’s disease in a sex-dependent manner.
(2023)Alzheimer’s disease (AD) is recognized as an age-related neurodegenerative disorder, characterized by the aggregation and deposition of amyloid-β (Aβ) in plaques and neurofibrillary tangles (NFTs) composed of aggregates ... -
Decoding damage-associated microglia in post mortem hippocampus of Alzheimer’s disease patients
Sánchez-Mejías, Elisabeth
; Mejías-Ortega, Marina; Navarro, Victoria; Gómez-Arboledas, Ángela; Núñez-Díaz, Cristina; Sánchez-Varo, Raquel María; Vizuete, María Luisa; Dávila-Cansino, José Carlos; Vitorica Ferrández, Javier; Gutiérrez-Pérez, Antonia[et al.] (2019-07-18)
The relationship between Alzheimer’s disease (AD) and neuroinflammation has become stronger since the identification of several genetic risk factors related to microglial function. Though the role of microglial cells in ... -
DEPTOR promotes bone marrow adipose tissue expansion in calorie restricted mice.
Elevated levels of fat in bones is a characteristic feature of osteoporosis and other skeletal disorders. While the molecular mechanism behind this shift between bone and fat formation remains incompletely understood, it ... -
Desarrollo de implantes protesicos personalizados mediante impresión 3D de metales para el tratamiento quirúrgico de defectos maxilares
Santos-Ruiz, Leonor; Ruiz Delgado, Francisco; Yáñez Vilas, José Ignacio; Granados Colocho, Juan Francisco; Monopoli, Donato; Rodríguez Acosta, Antonio Andrés[et al.] (2022)
La osteonecrosis mandibular es una patología que suele presentarse como efecto secundario de la radioterapia con que se tratan los procesos oncológicos de cabeza y cuello, o después de tratamientos prolongados con bifosfonatos. ... -
Detección y caracterización de virus emergentes de ADN de plantas para una agricultura sostenible
Grande-Pérez, Ana (2017-11-06)
Los virus de la familia Geminiviridae son virus de ADN monocatenario circular mono- o bipartito encapsulados en partículas geminadas que afectan a cultivos de plantas mono y dicotiledóneas. Los geminivirus son patógenos ... -
Development of in vitro systems to study IFN signalling in gilthead seabream (Sparus aurata)
González-Mariscal, J.A.; Fernández-Trujillo, M. Alejandra; Méndez, T.; Alonso-Sánchez, María del Carmen; García-Rosado, Esther; Álvarez-Herrero, María del Carmen; Béjar-Alvarado, Julia[et al.] (2014-12-11)
Type I interferon (IFN I) triggers specific signalling pathways leading to the activation of the innate immune defence of vertebrates against viral infections. In contrats, type II IFN (IFN II) is generally accepted to be ... -
Differential induction of the gilthead seabream Mx1, Mx2 and Mx3 promoters by IPNV and VHSV
González-Mariscal, J.A.; Fernández-Trujillo, M. Alejandra; Méndez, T.; Alonso-Sánchez, María del Carmen; García-Rosado, Esther; Álvarez-Herrero, María del Carmen; Béjar-Alvarado, Julia[et al.] (2014-10-07)
Type I interferon (IFN I) system triggers specific signalling pathways leading to the activation of the innate immune defence of vertebrates against viral infections. The complex expression regulation of Interferon Stimulated ... -
Discerning the relationship between geminiviral infection and vesicle trafficking using virus induced gene silencing
Cana Quijada, José Francisco; Rodríguez-Bejarano, Eduardo; Rosas-Díaz, Tábata Victoria; Lozano-Durán, Rosa (2017-06-26)
Tomato yellow leaf curl disease is one of the most important threats to tomato crops worldwide. One of its causal agents, Tomato yellow leaf curl Sardinian virus (TYLCSV) is a monopartite member of the genus Begomovirus ... -
Disentangling the contribution of tau and abeta pathologies in transgenic models of Alzheimer's disease
Sánchez-Varo, Raquel María; Fernández-Valenzuela, Juan José; Navarro, Victoria; Jiménez, Sebastián; Sánchez-Mejías, Elisabeth; Núñez-Díaz, Cristina; Gómez-Arboledas, Ángela; Vizuete, María Luisa; Dávila-Cansino, José Carlos; Vitorica Ferrández, Javier; Gutiérrez-Pérez, Antonia[et al.] (2018-07-20)
AIMS: Amyloid-beta (Abeta) deposits and intraneuronal hyperphosphorylated tau are major pathological hallmarks of Alzheimer’s disease (AD). The coexistence of these aggregates in AD brains leads to synaptic dysfunction, ... -
Dissecting the microglial response in transgenic models of amyloidogenesis and tauopathy
Sánchez-Varo, Raquel María; Fernández-Valenzuela, Juan José; Romero-Molina, Carmen; Sánchez-Mejías, Elisabeth; Gómez-Arboledas, Ángela; Núñez-Díaz, Cristina; Navarro, Victoria; Dávila-Cansino, José Carlos; Vitorica Ferrández, Javier; Gutiérrez-Pérez, Antonia[et al.] (2019-07-19)
Amyloid-beta (Abeta) peptide deposits and hyperphosphorylated tau protein (phospho-tau) accumulate in Alzheimer’s disease (AD) brains. These abnormal protein aggregates leads to glial activation, synaptic dysfunction, ... -
Dissecting the relevance of vesicle trafficking for the movement of geminiviruses
Cana Quijada, José Francisco; Morales Martínez, Pablo; Rosas-Díaz, Tábata Victoria; Navarro, José Antonio; Pallás, Vicente; Lozano-Durán, Rosa; Castillo-Garriga, Araceli; Rodríguez-Bejarano, Eduardo[et al.] (2022-09)
Tomato yellow leaf curl disease is one of the most important threats to tomato crops worldwide. One of its causal agents, Tomato yellow leaf curl Sardinian virus (TYLCSV), is a monopartite member of the genus Begomovirus ... -
Diversity of plaque-associated myeloid cells subtypes in human alzheimer’s disease brain
Mejías-Ortega, Marina; Sánchez-Mejías, Elisabeth; Muñoz-Castro, Clara; Trujillo-Estrada, Laura Isabel; Vizuete, María Luisa; Vitorica Ferrández, Javier; Gutiérrez-Pérez, Antonia[et al.] (2022)
Aims: Parenchymal microglia, as well other myeloid cells, have been postulated as a critical factor in Alzheimer´s disease (AD) pathogenesis since the identification of genetic risk factors related to their functions. ... -
Dopamine D4 receptor activation counteracts nigrostriatal pathway activation by morphine: relevance in drug addiction.
Rivera-Ramírez, Alicia; Suárez-Boomgaard, Diana; Gago-Calderón, Belén; Valderrama-Carvajal, Alejandra; Medina-Luque, José; Roales-Buján, Ruth; Fuxe, Kjell; De-la-Calle-Martín, Adelaida[et al.] (2013)
Morphine induces dopamine release in the caudate putamen (CPu), which promotes stereotyped behavior and habit learning for drug-seeking and –taking. Nigrostriatal pathway stimulation by morphine is due to a removal of tonic ... -
Dopamine D4 receptor counteracts morphine-induced changes in M opioid receptor signaling in the striosomes of the rat caudate putamen.
Rivera-Ramírez, Alicia; Valderrama-Carvajal, Alejandra; Roales-Buján, Ruth; Suárez-Boomgaard, Diana; Medina-Luque, José; Shumilov, Kirill; De-la-Calle-Martín, Adelaida[et al.] (2015-10-05)
Morphine is one of the most potent analgesic drugs used to relieve moderate to severe pain. After long-term use of morphine, neuroadaptive changes in the brain promotes tolerance, which result in a reduced sensitivity to ... -
Dopamine D4R restores morphine-induced impairment of adult neurogenesis in the subventricular zone
Gago-Calderón, Belén; Real-Avilés, María Ángeles; Ponce-Velasco, Marina; Rivera-Ramírez, Alicia (2021)
In the adult mammalian brain, neuroblasts from the subventricular zone (SVZ) migrate along the rostral migratory stream into the olfactory bulb, where they differentiate and synaptically integrate to contribute with the ... -
Dos herramientas bioinformáticas para el análisis de genomas de bacterias fitopatógenas
Los avances en tecnología de secuenciación han supuesto una cosiderable reducción en costo y tiempo a la hora de obtener genomas bacterianos completos. Es cada vez más frecuente, pues, secuenciar los genomas de las cepas ... -
Las dos proteínas Mx de lubina (Dicentrarchus labrax) responden de forma diferente a la infección por VNNV
Novel, Patricia; Fernández-Trujillo, M. Alejandra; Manchado, Manuel; Álvarez-Herrero, María del Carmen; Béjar-Alvarado, Julia (2013-10-01)
Las proteínas Mx son elementos clave en el estado antiviral desencadenado por el interferón tipo I en respuesta a las infecciones virales. En este trabajo se han identificado dos genes Mx en lubina (Dicentrarchus labrax), ... -
Dynamics of heterogeneous populations of Pseudomonas syringae within plant tissues reveal a diversity of interactions with potential evolutionary
Rufián Plaza, José Sebastián; Macho, Alberto P.; Corry, David S; Mansfield, John W; Arnold, Dawn L; Beuzón-López, Carmen del Rosario[et al.] (2014-07-17)
Bacterial populations have been traditionally assumed to be clonal, and as such, genetically and phenotipically identical. However, research carried out in the last few decades has proven this view naïve. Formation of ... -
El efector bacteriano HopZ1a aceita al regulador positivo de defensa ZIP1
Rueda-Blanco, Javier; Rufián Plaza, José Sebastián; López-Márquez, Diego; Beuzón-López, Carmen del Rosario; Ruiz-Albert, Francisco Javier (2017-06-26)
Durante la interacción planta-patógeno se producen una serie de eventos moleculares que determinan el resultado final de dicha interacción: multiplicación del patógeno y desarrollo de síntomas de enfermedad en plantas ... -
Effect of bone marrow-derived mesenchymal stem cells on congenital hydrocephalus in the hyh mouse
García-Bonilla, María; Shumilov, Kirill; Vitorica Ferrández, Javier; García-Martín, María Luisa; Muñoz, Carmen; Jiménez, Sebastián; Navarro, Victoria; García-Cuervo, Luisa; Cifuentes-Rueda, Manuel; Claros-Gil, Silvia; Andrades-Gómez, José Antonio; Guitérrez, Antonia; Páez-González, Patricia; Jiménez-Lara, Antonio Jesús[et al.] (2017-06-28)
Background Bone marrow-derived mesenchymal stem cells (BM-MSC) are considered as a potential therapeutic tool for neurodegenerative diseases due to their ability for migrating into damaged tissue. Additionally, these cells ...