
- RIUMA Principal
- Investigación
- Biología Celular, Genética y Fisiología - (BCGF)
- BCGF - Contribuciones a congresos científicos
- Listar BCGF - Contribuciones a congresos científicos por autor
Listar BCGF - Contribuciones a congresos científicos por autor "Páez-González, Patricia"
Mostrando ítems 1-13 de 13
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A sequential cell therapy to recover the ependymal cells in posthemorrhagic hydrocephalus.
López-de-San-Sebastián, Javier; Rodríguez-Pérez, Luis Manuel; González-García, Marcos; Jiménez-Lara, Antonio Jesús
; Páez-González, Patricia
(2022-09)
Background Germinal matrix haemorrhages and intraventricular haemorrhages (GMH/IVH) lead to posthemorrhagic hydrocephalus (PHH), a relevant cause of morbidity and mortality in the premature neonatal population. The ... -
Brain tissue recovery in obstructive congenital hydrocephalus after intraventricular transplantation of mesenchymal stem cells
García-Bonilla, María; Ojeda-Pérez, Betsaida; Shumilov, Kirill; Vitorica Ferrández, Javier; García-Martín, María Luisa; Muñoz, Carmen; Gutiérrez-Pérez, Antonia; Jiménez-Lara, Antonio Jesús
; Páez-González, Patricia
[et al.] (2018-10-29)
Introduction: Bone marrow-derived mesenchymal stem cells (BM-MSC) are a potential therapeutic tool due to their ability for migrating and producing neuroprotector factors when transplanted. The aim of this study was to ... -
Effect of bone marrow-derived mesenchymal stem cells on congenital hydrocephalus in the hyh mouse
García-Bonilla, María; Shumilov, Kirill; Vitorica Ferrández, Javier; García-Martín, María Luisa; Muñoz, Carmen; Jiménez, Sebastián; Navarro, Victoria; García-Cuervo, Luisa; Cifuentes-Rueda, Manuel; Claros-Gil, Silvia
; Andrades-Gómez, José Antonio
; Guitérrez, Antonia; Páez-González, Patricia
; Jiménez-Lara, Antonio Jesús
[et al.] (2017-06-28)
Background Bone marrow-derived mesenchymal stem cells (BM-MSC) are considered as a potential therapeutic tool for neurodegenerative diseases due to their ability for migrating into damaged tissue. Additionally, these cells ... -
Human Mesenchymal Stem Cells and its Exosomes in Posthemorrhagic Hydrocephalus: A Focus on Edema and Ependymal Repair
López-de-San-Sebastián, Javier; Rodríguez-Pérez, Luis Manuel; Anguita-Guardia, Alba; Jiménez-Lara, Antonio Jesús
; Páez-González, Patricia
(SRHSB 2024 Annual Conference, 2023-09-04)
Background Germinal matrix hemorrhages and intraventricular hemorrhages (GMH/IVH) often lead to posthemorrhagic hydrocephalus (PHH), a severe cause of morbidity and mortality in premature neonates. GMH/IVH is known to ... -
IPSC differentiation into ependymal progenitors to treat ventricular damage during hydrocephalus
Introduction: During both obstructive congenital hydrocephalus and post-hemorrhagic hydrocephalus additional pathological events are intimately associated with their ethiology: a) a detrimental inflammatory response; b) ... -
iPSC differentiation into ependymal progenitors to treat ventricular damage during hydrocephalus
Rodríguez-Pérez, Luis Manuel; Hidalgo-Díaz, Juan Antonio; Jiménez-Lara, Antonio Jesús
; Páez-González, Patricia
(2019-07-03)
Introduction: During both obstructive congenital hydrocephalus and post-hemorrhagic hydrocephalus additional pathological events are intimately associated with their ethiology: a) a detrimental inflammatory response; b) ... -
Long-time effects of an experimental therapy with mesenchymal stem cells in congenital hydrocephalus
García-Bonilla, María; Ojeda-Pérez, Betsaida; Shumilov, Kirill; Vitorica Ferrández, Javier; Guitérrez, Antonia; Páez-González, Patricia; Jiménez-Lara, Antonio Jesús
[et al.] (2019-07-03)
Introduction: Bone marrow-derived mesenchymal stem cells (BM-MSC) are a potential therapeutic tool due to their ability for migrating and producing neuroprotector factors when they are transplanted in other neurodegenerative ... -
A metabolite profile reveals the presence of neurodegenerative conditions according to severity of hydrocephalus
García-Bonilla, María; Shumilov, Kirill; García-Martín, María Luisa; Muñoz, María Carmen; Domínguez-Pinos, Dolores; Gutiérrez-Pérez, Antonia
; Páez-González, Patricia
; Jiménez-Lara, Antonio Jesús
[et al.] (2018-11-29)
Introduction: In obstructive congenital hydrocephalus, cerebrospinal fluid accumulation is associated with high intracranial pressure (ICP), ischemia/hypoxia, metabolic impairment, neuronal damage and astrocytic reaction. ... -
Multiciliated ependyma recovery through a sequential cell therapy in posthemorrhagic hydrocephalus.
López-de-San-Sebastián, Javier; Rodríguez-Pérez, Luis Manuel; González-García, Marcos; Páez-González, Patricia
; Jiménez-Lara, Antonio Jesús
(2023)
Posthemorrhagic hydrocephalus (PHH) is a significant cause for premature children’s morbidity, mortality, and peri/postnatal neurodevelopmental impairment. PHH is mainly triggered by germinal matrix hemorrhages (GMH) and ... -
Neural activity control of neural stem cells and SVZ niche response to brain injury
Páez-González, Patricia(2014-11-25)
Patricia Paez-Gonzalez Kuo Lab, Dept. of Cell Biology, Duke University Medical Center, NC,USA. Date: 11/16/2014 Utilizing stem cells in the adult brain hold great promise for regenerative medicine. Harnessing ability ... -
Neuropathological events in an animal model resembling human fetal post-hemorrhagic hydrocephalus
Introduction: In premature newborns, intraventricular hemorrhages (IVH) probably trigger the disruption of the neurogenic ventricular zone. Most of the cases with severe IVH develop post-hemorrhagic hydrocephalus (PHH). ... -
NG2 cells in an animal model of congenital hydrocephalus
Jiménez-Lara, Antonio Jesús; Ojeda-Pérez, Betsaida; García-Bonilla, María; Ruz-Maldonado, Inmaculada; Mateos-Grondona, Jesús
; Rodríguez-Pérez, Luis Manuel
; Páez-González, Patricia
[et al.] (2017-06-28)
NG2 cells are considered oligodendrocyte precursor cells (OPC). In pathological conditions, NG2 cells contribute to generate oligodendrocytes and reactive astrocytes. This study has been designed to uncover the role of NG2 ... -
Testing exosomes as a treatment for posthemorrhagic hydrocephalus.
López-de-San-Sebastián, Javier; Rodríguez-Pérez, Luis Manuel; Anguita-Guardia, Alba; Jiménez-Lara, Antonio Jesús
; Páez-González, Patricia
(2023)
Germinal matrix hemorrhages and intraventricular hemorrhages (GMH/IVH) lead to posthemorrhagic hydrocephalus (PHH), a severe cause of morbidity and mortality in premature neonates. GMH/IVH disrupts the ependyma, which forms ...