This research focused on the pre-service science teachers’ perceptions of Inquiry-Based Science Education (IBSE) in Spanish speaking contexts. Drawing on the PRIMAS questionnaire and extensive adaptations, the PTIP questionnaire, a 25-item instrument was developed to gauge pre-service teachers’ perspectives on IBSE. The questionnaire effectively measures four dimensions through rigorous statistical validation: IBSE teaching practice, IBSE students’ applicability, and internal and external difficulties associated with the inquiry approach. Employing K-means cluster analysis, three distinct profiles emerged, elucidating pre-service teachers’ varying perceptions and readiness to embrace IBSE. Profile A embodies fervent advocates of IBSE, while profile B and C showcases strong support with moderate reservations about its challenges and a more ambivalent stance, respectively. This research contributes a valuable tool for understanding and enhancing pre-service teacher education, fostering the adoption of IBSE
