Periventricular extracellular oedema, myelin damage, inflammation, and glial reactions are common
neuropathological events that occur in the brain in congenital hydrocephalus. The periventricular white matter is the
most affected region. The present study aimed to identify altered molecular and cellular biomarkers in the neocortex
that can function as potential therapeutic targets to both treat and evaluate recovery from these neurodegenerative
conditions. The hyh mouse model of hereditary hydrocephalus was used for this purpose.
