Long COVID syndrome has been recognized as a public health problem. Digital physiotherapy
practice is an alternative that can better meet the needs of patients. The aim of this review was
to synthesize the evidence of digital physiotherapy practice in Long COVID patients. A systematic
review was carried out until December 2022. The review was complemented by an assessment of the
risk of bias and methodological quality. A narrative synthesis of results was conducted, including
subgroup analyses by intervention and clinical outcomes. Six articles, including 540 participants, were
selected. Five articles were considered of high enough methodological quality. Parallel-group, singleblind,
randomized controlled trials were the most commonly used research design. Tele-supervised
home-based exercise training was the most commonly used intervention. Great heterogeneity in
clinical outcomes and measurement tools was found. A subgroup analysis showed that digital
physiotherapy is effective in improving clinical outcomes. Significant differences in favor of digital
interventions over usual care were reported. Nevertheless, discrepancies regarding effectiveness
were found. Improvements in clinical outcomes with digital physiotherapy were found to be at least
non-inferior to usual care. This review provides new evidence that digital physiotherapy practice is
an appropriate intervention for Long COVID patients, despite the inherent limitations of the review.
Registration: CRD42022379004.
