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dc.contributor.authorClemente Garulo, Daniel
dc.contributor.authorNúñez-Cuadros, Esmeralda
dc.contributor.authorCamacho Lovillo, Marisol
dc.contributor.authorCalzada-Hernández, Joan
dc.contributor.authorGuillén Martín, Sara
dc.contributor.authorFernández Silveira, Laura
dc.contributor.authorLirola-Cruz, María José
dc.contributor.authorTagarro, Alfredo
dc.contributor.authorAlcobendas Rueda, Rosa María
dc.contributor.authorLópez López, Agustín
dc.contributor.authorSatrustegi Aritziturri, Miren
dc.contributor.authorCalvo, Cristina
dc.date.accessioned2023-07-19T11:10:31Z
dc.date.available2023-07-19T11:10:31Z
dc.date.issued2023
dc.identifier.citationClemente Garulo, D., Núñez-Cuadros, E., Camacho Lovillo, M. et al. Position statement on infection screening, prophylaxis, and vaccination in pediatric patients with rheumatic diseases and immunosuppressive therapies, part 2: infection prophylaxis. Eur J Pediatr (2023). https://doi.org/10.1007/s00431-023-05080-3es_ES
dc.identifier.urihttps://hdl.handle.net/10630/27304
dc.description.abstractThis study aims to provide practical recommendations on prophylaxis for infection in pediatric patients with immune-mediated rheumatic diseases receiving/scheduled to receive immunosuppressive therapy. A qualitative approach was applied. A narrative literature review was performed via Medline. Primary searches were conducted using MeSH terms and free text to identify articles that analyzed data on infections and vaccinations in pediatric patients with immune-mediated rheumatic diseases receiving immunosuppressive therapy. The results were presented and discussed in a nominal group meeting comprising a committee of 12 pediatric rheumatologists from the Prevention and Treatment of Infections Working Group of the Spanish Society of Pediatric Rheumatology. Several recommendations were generated. A consensus procedure was implemented via a Delphi process that was extended to members of the Spanish Society of Pediatric Rheumatology and the Vaccine Advisory Committee of the Spanish Association of Pediatrics. Participants produced a score ranging from 0 (completely disagree) to 10 (completely agree). Agreement was considered to have been reached if at least 70% of participants voted ≥ 7. The literature review included more than 400 articles. Overall, 63 recommendations were generated (23 on infection prophylaxis) and voted by 59 pediatric rheumatologists and other pediatric specialists, all of whom achieved the pre-established level of agreement. The recommendations on prophylaxis of infection cover vaccination and prophylaxis against varicella zoster virus, tuberculosis, Pneumocystis jiroveccii, and invasive fungal infections in pediatric patients with immune-mediated rheumatic diseases receiving/scheduled to receive immunosuppressive therapy. Conclusion: Based on current evidence and a Delphi process, we provided consensus and updated recommendations on prophylaxis and treatment of infections to guide those caring for pediatric rheumatology patients.es_ES
dc.description.sponsorshipFunding for open access charge: Universidad de Málaga/CBUAes_ES
dc.language.isoenges_ES
dc.publisherSpringeres_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectInfecciones en niñoses_ES
dc.subjectTerapéuticaes_ES
dc.subject.otherVaccinationes_ES
dc.subject.otherProphylaxises_ES
dc.subject.otherTuberculosises_ES
dc.subject.otherVaricellaes_ES
dc.subject.otherHerpes zoster viruses_ES
dc.subject.otherPneumocystis jiroveciies_ES
dc.subject.otherImmunemediated rheumatic diseaseses_ES
dc.subject.otherConsensuses_ES
dc.titlePosition statement on infection screening, prophylaxis, and vaccination in pediatric patients with rheumatic diseases and immunosuppressive therapies, part 2: infection prophylaxises_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.centroFacultad de Medicinaes_ES
dc.identifier.doi10.1007/s00431-023-05080-3
dc.rights.ccAtribución 4.0 Internacional*
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones_ES


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