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Allergen exposure boosts peripheral Th9 responses in patients with local allergic rhinitis
dc.contributor.author | Palomares, Francisca | |
dc.contributor.author | Aranda, Carlos José | |
dc.contributor.author | Saenz de Santa María-García, Rocío | |
dc.contributor.author | Mayorga Mayorga, Cristobalina | |
dc.contributor.author | Rondón Segovia, Carmen | |
dc.contributor.author | Testera Montes, Almudena | |
dc.contributor.author | Alba-Linero, Carmen | |
dc.contributor.author | Bentabol-Ramos, Guillermo | |
dc.contributor.author | Torres-Jaén, María Josefa | |
dc.contributor.author | Eguiluz-Gracia, Ibón | |
dc.date.accessioned | 2023-06-06T09:16:41Z | |
dc.date.available | 2023-06-06T09:16:41Z | |
dc.date.issued | 2023 | |
dc.identifier.citation | Palomares, Testera-Montes, A., Aranda, C. J., Alba-Linero, C., Sáenz de Santa María-García, R., Bentabol-Ramos, G., Mayorga, C., Torres, M. J., Rondon, C., & Eguiluz-Gracia, I. (2023). Allergen exposure boosts peripheral Th9 responses in patients with local allergic rhinitis. International Forum of Allergy & Rhinology. https://doi.org/10.1002/alr.23175 | es_ES |
dc.identifier.uri | https://hdl.handle.net/10630/26815 | |
dc.description.abstract | Key points ∙ Intranasal allergen exposure increases peripheral total Th2 and Th9 cells in patients with local allergic rhinitis (LAR). ∙ Peripheral T-cell response seems dominated by Th9 cells in patients with LAR, whereas Th2 responses prevail in patients with allergic rhinitis. ∙ Our results identify Th9 cells as potential therapeutic targets for patients with LAR. | es_ES |
dc.description.sponsorship | Instituto de Salud Carlos III (ISCIII) of the Spanish Ministry of Science and Competitiveness, Grant/Award Number: PI20/01715; Regional Ministry of Health of Andalucia through research projects, Grant/Award Numbers: PI-0346-2016, PI-0176-2018; Regional Ministry of Education of Andalucia through a research project, Grant/Award Number: P20-00405; Francisca Palomares holds a Senior Postdoctoral Program contract, Grant/Award Number: RH-0028-2021; Almudena Testera-Montes a “Rio Hortega” contract, Grant/Award Number: CM20/00160; Carlos Jose Aranda a “Sara Borrell” contract, Grant/Award Number: CD21/00034; Carmen Alba-Linero a “Río Hortega” contract, Grant/Award Number: CM21/00262; Ibon Eguiluz-Gracia a “Juan Rodes” contract, Grant/Award Number: JR19/00029; Cristobalina Mayorga holds a “Nicolas Monardes” contract, Grant/Award Number: RC-0004-2021; Asma, ReaccionesAdversas y Alérgicas-ARADyAL, Grant/ Award Number: RD16/0006/0001; Redes de InvestigacionCooperativaOrientadas al Resultado en Salud: Enfermedades Inflamatorias, Grant/Award Number: RD21/0002/0008 Funding for open access charge: Universidad de Málaga/CBUA | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Wiley | es_ES |
dc.rights | Atribución-NoComercial 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | * |
dc.subject | Rinitis | es_ES |
dc.subject | Alergia | es_ES |
dc.subject.other | Allergens | es_ES |
dc.subject.other | Allergic rhinitis | es_ES |
dc.subject.other | Biomarker | es_ES |
dc.subject.other | Inhalation allergen challenge | es_ES |
dc.subject.other | Rhinitis | es_ES |
dc.subject.other | Therapeutics | es_ES |
dc.title | Allergen exposure boosts peripheral Th9 responses in patients with local allergic rhinitis | es_ES |
dc.type | journal article | es_ES |
dc.centro | Facultad de Medicina | es_ES |
dc.identifier.doi | https://doi.org/10.1002/alr.23175 | |
dc.type.hasVersion | VoR | es_ES |
dc.departamento | Medicina y Dermatología | |
dc.rights.accessRights | open access | es_ES |