Key points
∙ Intranasal allergen exposure increases peripheral total Th2 and Th9 cells in patients with local allergic rhinitis (LAR).
∙ Peripheral T-cell response seems dominated by Th9 cells in patients with LAR, whereas Th2 responses prevail in patients with allergic rhinitis.
∙ Our results identify Th9 cells as potential therapeutic targets for patients with LAR.
