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dc.contributor.authorCana Quijada, José Francisco
dc.contributor.authorMorales Martínez, Pablo
dc.contributor.authorRosas-Díaz, Tábata Victoria
dc.contributor.authorNavarro, José Antonio
dc.contributor.authorPallás, Vicente
dc.contributor.authorLozano-Durán, Rosa
dc.contributor.authorCastillo-Garriga, Araceli 
dc.contributor.authorRodríguez-Bejarano, Eduardo 
dc.date.accessioned2022-10-04T11:34:24Z
dc.date.available2022-10-04T11:34:24Z
dc.date.issued2022-09
dc.identifier.urihttps://hdl.handle.net/10630/25170
dc.description.abstractTomato yellow leaf curl disease is one of the most important threats to tomato crops worldwide. One of its causal agents, Tomato yellow leaf curl Sardinian virus (TYLCSV), is a monopartite member of the genus Begomovirus from the family Geminiviridae. Due to the few proteins encoded by their viral genome, geminiviruses rely heavily on host cellular machinery and interact with a wide range of plant proteins to complete all processes required for infection, such as viral replication, movement and suppression or evasion of plant defense mechanisms. Therefore, identifying the host proteins involved in viral infection will be an essential step towards understanding the mechanisms underlying this process. Using a reverse genetic approach our group identified a series of genes involved in vesicle trafficking, which affect geminivirus infection. Four of them are essential as their silencing produce a complete abolishment of TYLCSV infection (-COP, ARF1, CHC1, and CHC2). However, these genes do not affect TYLCSV replication. A series of experiments using confocal microscopy and viral proteins bound to fluorescent markers have been carried out to determine the effect of inhibiting vesicle trafficking over the subcellular localization of TYLCSV’s movement proteins. The biological relevance of vesicle trafficking during geminivirus infection will be presented and discussed.es_ES
dc.description.sponsorshipUniversidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.es_ES
dc.language.isoenges_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.subjectTomates -- enfermedades y plagases_ES
dc.subject.otherVirus fitopatógenoses_ES
dc.subject.otherProteínas vegetaleses_ES
dc.subject.otherTomates - Enfermedades y plagases_ES
dc.subject.otherTomates - Variedadeses_ES
dc.subject.otherGeminiviruses_ES
dc.subject.otherExtracellular vesicleses_ES
dc.subject.otherBegomoviruses_ES
dc.subject.otherViral movementes_ES
dc.subject.otherVesicle traffickinges_ES
dc.titleDissecting the relevance of vesicle trafficking for the movement of geminiviruseses_ES
dc.title.alternativeUnraveling the importance of vesicle trafficking for the movement of geminiviruseses_ES
dc.typeinfo:eu-repo/semantics/conferenceObjectes_ES
dc.centroFacultad de Cienciases_ES
dc.relation.eventtitleXVI Reunión de Biología Molecular de Plantases_ES
dc.relation.eventplaceSevillaes_ES
dc.relation.eventdate14 de septiembre de 2022es_ES


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