Listar MIC - Artículos por título
Mostrando ítems 115-134 de 169
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"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection.
(JoVE, 2019)Despite the exceptional infectivity of the hepatitis B virus (HBV) in vivo, where only three viral genomes can result in a chronicity of experimentally infected chimpanzees, most in vitro models require several hundreds ... -
Longitudinal observation and decline of neutralizing antibody responses in the three months following SARS-CoV-2 infection in humans
(2020)Antibody responses to SARS-CoV-2 can be detected in most infected individuals 10-15 d after the onset of COVID-19 symptoms. However, due to the recent emergence of SARS-CoV-2 in the human population, it is not known how ... -
Lymphocystis disease virus (LCDV-Sa), polyomavirus 1 (SaPyV1) and papillomavirus 1 (SaPV1) in samples of Mediterranean gilthead seabream
(Inter-Research Science Publisher, 2019-01-10)Lymphocystis disease, caused by the iridovirus lymphocystis disease virus (LCDV), is characterized by the appearance of tumour-like lesions on the skin of affected animals associated with several environmental factors ... -
Lymphocystis disease virus: its importance in aquaculture
(Wiley, 2015-09-28)Lymphocystis disease virus (LCDV) is the causative agent of a well-known fish viral disease that is characterized by hypertrophy of fibroblastic cells in the connective tissue. This viral disease affects more than 125 ... -
Mangotoxin production of Pseudomonas syringae pv. syringae is regulated by MgoA.
Carrión Bravo, Víctor José; Van der Voort, Menno; Arrebola-Díez, Eva María
; Gutiérrez Barranquero, José Antonio; De-Vicente-Moreno, Antonio; Raaijmakers, Jos M.; Cazorla-López, Francisco Manuel[et al.] (BMC, 2014-02-21)
Background: The antimetabolite mangotoxin is a key factor in virulence of Pseudomonas syringae pv. syringae strains which cause apical necrosis of mango trees. Previous studies showed that mangotoxin biosynthesis is governed ... -
Metabolic stasis in an ancient symbiosis: genome-scale metabolic networks from two Blattabacterium cuenoti strains, primary endosymbionts of cockroaches
González-Doménech, Carmen María; Belda, Eugeni; Patiño-Navarrete, Rafael; Moya, Andrés; Peretó, Juli (Springer Nature, 2012-01-18)
Cockroaches are terrestrial insects that strikingly eliminate waste nitrogen as ammonia instead of uric acid. Blattabacterium cuenoti strains Bge and Pam are the obligate primary endosymbionts of the cockroaches Blattella ... -
Microalgae and cyanobacteria as microbial substrate and their influence on the potential postbiotic capability of a bacterial probiotic
Domínguez Maqueda, Marta; Pérez Gómez, Olivia; García Márquez, Jorge; Espinosa Ruíz, Cristóbal; Cuesta, Alberto; Esteban, Mª. Ángeles; Alarcón López, Francisco Javier; Cárdenas, Casimiro; Tapia-Paniagua, Silvana Teresa; Balebona-Accino, María del Carmen; Moriñigo-Gutiérrez, Miguel Ángel[et al.] (Wiley, 2024)
Postbiotics are metabolic by-products from microorganisms that provide health benefits to the host. Their secretion can be influenced by various conditions affecting bacterial metabolism. This study presents a novel ... -
Microalgal and Cyanobacterial Biomasses Modified the Activity of Extracellular Products from Bacillus pumilus: An In Vitro and In Vivo Assessment
García-Márquez, Jorge; Galafat Díaz, Alba; Molina-Roque, Luis; Domínguez-Maqueda, Marta; De las Heras, Verónica; Simó-Mirabet, Paula; Vizcaíno, Antonio J.; Martos-Sitcha, Juan Antonio; Alarcón López, Francisco Javier; Moriñigo-Gutiérrez, Miguel Ángel; Balebona-Accino, María del Carmen[et al.] (2024-09-11)
This study investigates the postbiotic potential of extracellular products (ECPs) from Bacillus pumilus strains cultivated on microalgae-supplemented media. We assessed enzymatic and antimicrobial activities to select ECPs ... -
Microbiota composition and intestinal integrity remain unaltered after the inclusion of hydrolysed Nannochloropsis gaditana in Sparus aurata diet
Cerezo Ortega, Isabel M.; Di Zeo-Sánchez, Daniel Enrique; García-Márquez, Jorge; Ruiz Jarabo, Ignacio; Sáez-Casado, M.I.; Balebona-Accino, María del Carmen; Moriñigo-Gutiérrez, Miguel Ángel; Tapia-Paniagua, Silvana Teresa[et al.] (Springer Nature, 2021)
The use of lysed microalgae in the diet of carnivorous fish can increase the bioavailability of proteins and bioactive compounds, such as unsaturated fatty acids or vitamins in the digestive tract. These are essential ... -
Modulation of Intestinal Microbiota in Solea senegalensis Fed Low Dietary Level of Ulva ohnoi
Tapia-Paniagua, Silvana Teresa; Fumanal, Milagros Elena; Anguís, Victoria; Fernández-Díaz, Catalina; Alarcón, Francisco Javier; Moriñigo-Gutiérrez, Miguel Ángel; Balebona-Accino, María del Carmen[et al.] (Frontiers, 2019)
Gastrointestinal (GI) microbiota has a relevant role in animal nutrition, modulation of the immune system and protection against pathogen invasion. Interest in algae as source of nutrients and functional ingredients for ... -
Molecular evolution of nitric oxide synthases in metazoans.
Muñoz-Chápuli-Oriol, Ramón; González-Doménech, Carmen María (2010-08-09)
Nitric oxide synthases (NOS), the enzymes responsible for the NO synthesis, are present in all eukaryotes. Three isoforms (neuronal, inducible and endothelial), encoded by different loci, have been described in vertebrates, ... -
Molecular intraspecific characterization of Photobacterium damselae ssp. damselae strains affecting cultured marine fish
(Wiley, 2010-05-07)In this study, the techniques tested are confirmed as good tools for molecular typing, because they allow discrimination between P. damselae ssp. damselae strains isolated within the same outbreak. In addition, ERIC-PCR and ... -
MX2-mediated innate immunity against HIV-1 is regulated by serine phosphorylation
(Springer Nature, 2021)The antiviral cytokine interferon activates expression of interferon-stimulated genes to establish an antiviral state. Myxovirus resistance 2 (MX2, also known as MxB) is an interferon-stimulated gene that inhibits the ... -
Nervous necrosis virus (NNV) vaccination of carrier Senegalese sole (Solea senegalensis).
(Elsevier, 2023)Viral encephalopathy and retinopathy (VER), caused by nervous necrosis virus (NNV), is one of the most threatening diseases affecting marine farmed fish, especially in early developmental stages. In addition, subclinica ... -
Neutralization potency of monoclonal antibodies recognizing dominant and subdominant epitopes on SARS-CoV-2 Spike is impacted by the B.1.1.7 variant
(Elsevier, 2021)Interaction of the SARS-CoV-2 Spike receptor binding domain (RBD) with the receptor ACE2 on host cells is essential for viral entry. RBD is the dominant target for neutralizing antibodies, and several neutralizing epitopes ... -
Pantoea agglomerans as a New Etiological Agent of a Bacterial Necrotic Disease of Mango Trees.
Gutiérrez Barranquero, José Antonio; Cazorla-López, Francisco Manuel; Torés, Juan Antonio; De-Vicente-Moreno, Antonio (American Phytopathological Society, 2018)
Bacterial apical necrosis of mango trees, a disease elicited by Pseudomonas syringae pv. syringae, is a primary limiting factor of mango crop production in the Mediterranean region. In this study, a collection of bacterial ... -
Pathogen-induced activation of disease-suppressive functions in the endophytic root microbiome
(Science, 2019-11-01)Microorganisms living inside plants can promote plant growth and health, but their genomic and functional diversity remain largely elusive. Here, metagenomics and network inference show that fungal infection of plant roots ... -
Peer review of teaching: using the nominal group technique to improve a program in a university setting with no previous experience
Barrios-Rodríguez, Rocío; Salcedo-Bellido, Inmaculada; Jiménez-Moleón, José Juan; Lozano-Lorca, Macarena; Galiano-Castillo, Noelia; Cobos, Enrique José; Vílchez-Rienda, José Dámaso; Olmedo-Requena, Rocío; Amezcua-Prieto, Carmen; Martín-Peláez, Sandra; González-Doménech, Carmen María; Arrebola Moreno, Juan Pedro; Rica, Raúl A.; García-Rubiño, María Eugenia; Requena, Pilar[et al.] (International Consortium for Educational Development, 2022-03-15)
Peer Review of Teaching (PRT) programmes provide benefits for both the observer and the observed colleague, but there are no PRT programmes implemented in Spanish Universities. A PRT pilot programme involving 14 volunteer ... -
Persistence of Lymphocystis Disease Virus (LCDV) in Seawater
Leiva Rebollo, Rocío; Labella Vera, Alejandro Manuel; Jiménez Valverde, Estefanía; Castro-López, María Dolores; Borrego-García, Juan José (Springer Link, 2020-02-21)
Lymphocystis disease virus (LCDV), the causative agent of lymphocystis disease (LCD), is a waterborne pathogen that uses the external surfaces, including the gills, as portals to gain access to fsh host. However, there ... -
Phosphodiesterase-induced cAMP degradation restricts hepatitis B virus infection.
(The Royal Society, 2019-04-08)Hepatitis B virus (HBV) entry into hepatocytes is mediated via a high-affinity interaction between the preS1 glycoprotein and sodium/bile acid cotransporting polypeptide (NTCP). To date, in vitro model systems rely on high ...