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Role of severe acute respiratory syndrome Coronavirus Viroporins E, 3a, and 8a in replication and pathogenesis
(American Society for Microbiology, 2018)Viroporins are viral proteins with ion channel (IC) activity that play an important role in several processes, including virus replication and pathogenesis. While many coronaviruses (CoVs) encode two viroporins, severe ... -
S- and N-doped carbon quantum dots: Surface chemistry dependent antibacterial activity.
Travlou, Nikolina; Giannakoudakis, Dimitrios; Algarra-González, Manuel; Labella Vera, Alejandro Manuel; Rodríguez-Castellón, Enrique
; Bandosz, Teresa J.[et al.] (Elsevier, 2018)
Sulfur and nitrogen-doped carbons quantum dots (S-CQDs and N-CQDs) were obtained using a simple hydrothermal treatment of S- or N-containing organic compounds/polymers. They were evaluated for their bactericidal activity ... -
Safety and efficacy of dolutegravir plus rilpivirine in treatment-experienced HIV-Infected Patients: the DORIVIR study
Palacios-Muñoz, María Rosario; Mayorga, María Luisa; González-Doménech, Carmen María; Hidalgo Tenorio, Carmen; Gálvez, Carmen; Muñoz Medina, Leopoldo; de la Torre, Javier; Lozano, Ana; Castaño, Manuel; Omar, Mohamed; Santos-González, Jesús Leandro[et al.] (SAGE, 2018-01)
Objectives: To analyze the efficacy and safety of dolutegravir/rilpivirine (DTG/RPV) in HIV-infected patients who switched from any other antiretroviral therapy (ART). Methods: Open-label, multicenter study including ... -
Selection of putative probiotics based on antigen-antibody cross-reaction with Photobacterium damselae subsp. piscicida and Vibrio harveyi for use in Senegalese sole (Solea senegalensis)
Medina, Alberto; Moriñigo-Gutiérrez, Miguel Ángel; Arijo-Andrade, Salvador (Elsevier, 2020-07)
Probiotics can be used to reduce disease outbreaks in aquaculture. Some of them are characterised by their antagonistic activity against pathogens or the stimulation of the fish immune response, including the production of ... -
Severe acute respiratory syndrome coronavirus E protein transports calcium ions and activates the NLRP3 inflammasome
(Elsevier, 2015)Severe acute respiratory syndrome coronavirus (SARS-CoV) envelope (E) protein is a viroporin involved in virulence. E protein ion channel (IC) activity is specifically correlated with enhanced pulmonary damage, edema ... -
Severe acute respiratory syndrome coronavirus envelope protein ion channel activity promotes virus fitness and pathogenesis
(2014)Deletion of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) envelope (E) gene attenuates the virus. E gene encodes a small multifunctional protein that possesses ion channel (IC) activity, an important function ... -
Severe acute respiratory syndrome coronavirus envelope protein regulates cell stress response and apoptosis.
(PLOS, 2011)Severe acute respiratory syndrome virus (SARS-CoV) that lacks the envelope (E) gene (rSARS-CoV-ΔE) is attenuated in vivo. To identify factors that contribute to rSARS-CoV-ΔE attenuation, gene expression in cells infected ... -
Severe acute respiratory syndrome coronaviruses with mutations in the E protein are attenuated and promising vaccine candidates
(ASM Journals, 2015)Severe acute respiratory syndrome coronavirus (SARS-CoV) causes a respiratory disease with a mortality rate of 10%. A mouse-adapted SARS-CoV (SARS-CoV-MA15) lacking the envelope (E) protein (rSARS-CoV-MA15-ΔE) is attenuated ... -
Sífilis e infección por el virus de la inmunodeficiencia humana: una endemia en hombres que tienen sexo con hombres.
González-Doménech, Carmen María; Antequera Martín-Portugués, Isabel; Clavijo-Frutos, Encarnación; Márquez-Solero, Manuel; Santos-González, Jesús Leandro; Palacios-Muñoz, María Rosario[et al.] (Elsevier, 2014-10-22)
Objective: to analyse epidemiological, clinical, and analytical features of HIV-infected men who have sex with men (MSM) diagnosed with syphilis in the Infectious Diseases Unit (Hospital Virgen de la Victoria, Málaga, ... -
SpPdp11 Administration in Diet Modified the Transcriptomic Response and Its Microbiota Associated in Mechanically Induced Wound Sparus aurata Skin
Cerezo Ortega, Isabel M.; Pérez-Gómez, Olivia; Bautista-Moreno, Rocío; Seoane Zonjic, Pedro; Esteban, María Ángeles; Balebona-Accino, María del Carmen; Moriñigo-Gutiérrez, Miguel Ángel; Tapia-Paniagua, Silvana Teresa[et al.] (MDPI, 2023)
Skin lesions are a frequent fact associated with intensive conditions affecting farmed fish. Knowing that the use of probiotics can improve fish skin health, SpPdp11 dietary administration has demonstrated beneficial effects ... -
Sppdp11 administration in diet modified the transcriptomic response and its microbiota associated in mechanically induced wound Sparus aurata skin.
Cerezo Ortega, Isabel M.; Pérez-Gómez, Olivia; Bautista-Moreno, Rocío; Seoane, Pedro; Esteban-Abad, María Ángeles (IOAP-MDPI, 2023-01-04)
Skin lesions are a frequent fact associated with intensive conditions affecting farmed fish. Knowing that the use of probiotics can improve fish skin health, SpPdp11 dietary administration has demonstrated beneficial ... -
Subcellular location and topology of severe acute respiratory syndrome coronavirus envelope protein
(Elsevier, 2011)Severe acute respiratory syndrome (SARS) coronavirus (CoV) envelope (E) protein is a transmembrane protein. Several subcellular locations and topological conformations of E protein have been proposed. To identify the correct ... -
Suppression of Chitin-Triggered Immunity by Plant Fungal Pathogens: A Case Study of the Cucurbit Powdery Mildew Fungus Podosphaera xanthii.
Bakhat, Nisrine; Vielba-Fernández, Alejandra; Padilla-Roji, Isabel; Martínez-Cruz, Jesús; Polonio, Álvaro; Fernández-Ortuño, Dolores; Pérez-García, Alejandro[et al.] (MDPI, 2023-07-21)
Fungal pathogens are significant plant-destroying microorganisms that present an increasing threat to the world’s crop production. Chitin is a crucial component of fungal cell walls and a conserved MAMP (microbe-associated ... -
Surveillance of Viruses in Wild Fish Populations in Areas around the Gulf of Cadiz (South Atlantic Iberian Peninsula)
(2014-09-19)This report describes a viral epidemiological study of wild fish around the Gulf of Cadiz (southwestern Iberian Peninsula) and is focused on infectious pancreatic necrosis virus (IPNV), viral hemorrhagic septicemia virus ... -
Synergic effect of metabolic syndrome and lipodystrophy on oxidative stress and inflammation process in treated HIV-patients.
González-Doménech, Carmen María; Plaza-Andrades, Isaac; Garrido-Sánchez, Lourdes; Queipo-Ortuño, María Isabel (Elsevier, 2022-06-06)
The aim of this study was to assess the effect of lipodystrophy (LD) associated to metabolic syndrome (MS) on oxidative stress and inflammation in a cohort of 243 HIV-infected patients with MS, all of them under three ... -
T cell immunity to Zika virus targets immunodominant epitopes that show cross-reactivity with other Flaviviruses.
(Springer Nature, 2018)Zika virus (ZIKV) Infection has several outcomes from asymptomatic exposure to rash, conjunctivitis, Guillain-Barré syndrome or congenital Zika syndrome. Analysis of ZIKV immunity is confounded by the fact that several ... -
Tetraselmis suecica and Porphyridium cruentum exopolysaccharides show anti-VHSV activity on RTG-2 cells
Parra-Riofrio, Geovanna; Moreno, Patricia; García-Rosado, Esther; Alonso-Sánchez, María del Carmen; Uribe-Tapia, Eduardo; Abdala-Díaz, Roberto Teófilo; Béjar-Alvarado, Julia[et al.] (Springer, 2023)
The use of functional feed additives is an important approach to both, prevent and fight, viral diseases in aquaculture. In this regard, microalgae-derived products, and, more specifically, microalgal exopolysaccharides ... -
The Compound 2-Hexyl, 5-Propyl Resorcinol has a key role in biofilm formation by the biocontrol rhizobacterium Pseudomonas chlororaphis PCL1606
Calderón, Claudia E.; Tienda Serrano, Sandra; Heredia Ponce, Zaira María; Arrebola-Díez, Eva María; Cárcamo-Oyarce, Gerardo; Eberl, Leo; Cazorla-López, Francisco Manuel[et al.] (Frontiers, 2019-02-28)
The production of the compound 2-hexyl-5-propyl resorcinol (HPR) by the biocontrol rhizobacterium Pseudomonas chlororaphis PCL1606 (PcPCL1606) is crucial for fungal antagonism and biocontrol activity that protects plants ... -
The extracellular matrix protects Bacillus subtilis colonies from Pseudomonas invasion and modulates plant co-colonization.
Molina-Santiago, Carlos; Pearson, John; Navarro, Yurena; Berlanga-Clavero, María Victoria; Caraballo-Rodríguez, Andrés Mauricio; Petras, Daniel; García Martín, Maria Luisa; Lamon, Gaelle; Habenstein, Birgit; Cazorla-López, Francisco Manuel; De-Vicente-Moreno, Antonio; Loquet, Antoine; Dorrestein, Pieter; Romero-Hinojosa, Diego Francisco[et al.] (Springer Nature, 2019-04-23)
Bacteria of the genera Pseudomonas and Bacillus can promote plant growth and protect plants from pathogens. However, the interactions between these plant-beneficial bacteria are understudied. Here, we explore the interaction ... -
The First Isolation of Photobacterium damselae subsp. damselae from Asian Seabass Lates calcarifer
(The Japanese Society of Fish Pathology, 2009-04-01)After transporting Asian seabass Lates calcarifer from a fish farm to the Burapha University facilities, they began to die. The affected or moribund fish exhibited abdominal swelling, yellowish decoloration around the ...