MIC - Artículos
Envíos recientes
-
Pathogen-induced activation of disease-suppressive functions in the endophytic root microbiome
(Science, 2019-11-01)Microorganisms living inside plants can promote plant growth and health, but their genomic and functional diversity remain largely elusive. Here, metagenomics and network inference show that fungal infection of plant roots ... -
Application of a new real-time polymerase chain reaction assay for surveillance studies of lymphocystis disease virus in farmed gilthead seabream
Valverde, Estefanía J.; Cano, Irene; Labella-Vera, Alejandro Manuel; Borrego-García, Juan José
; Castro-López, María Dolores (BMC, 2016-04-06)
Background: Lymphocystis disease (LCD) is the main viral infection reported to affect cultured gilthead seabream (Sparus aurata) in Europe. The existence of subclinical Lymphocystis disease virus (LCDV) infection in this ... -
Surveillance of Viruses in Wild Fish Populations in Areas around the Gulf of Cadiz (South Atlantic Iberian Peninsula)
(2014-09-19)This report describes a viral epidemiological study of wild fish around the Gulf of Cadiz (southwestern Iberian Peninsula) and is focused on infectious pancreatic necrosis virus (IPNV), viral hemorrhagic septicemia virus ... -
Identification of the mechanisms causing reversion to virulence in an attenuated SARS-CoV for the design of a genetically stable vaccine
(Public Library of Science, 2015)A SARS-CoV lacking the full-length E gene (SARS-CoV-∆E) was attenuated and an effective vaccine. Here, we show that this mutant virus regained fitness after serial passages in cell culture or in vivo, resulting in the ... -
The PDZ-binding motif of severe acute respiratory syndrome coronavirus envelope protein is a determinant of viral pathogenesis
(2014)A recombinant severe acute respiratory syndrome coronavirus (SARS-CoV) lacking the envelope (E) protein is attenuated in vivo. Here we report that E protein PDZ-binding motif (PBM), a domain involved in protein-protein ... -
Severe acute respiratory syndrome coronavirus envelope protein ion channel activity promotes virus fitness and pathogenesis
(2014)Deletion of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) envelope (E) gene attenuates the virus. E gene encodes a small multifunctional protein that possesses ion channel (IC) activity, an important function ... -
Inhibition of NF-κB-mediated inflammation in severe acute respiratory syndrome coronavirus-infected mice increases survival
(ASM Journals, 2014)Severe acute respiratory syndrome coronavirus (SARS-CoV) is the etiological agent of a respiratory disease that has a 10% mortality rate. We previously showed that SARS-CoV lacking the E gene (SARS-CoV-ΔE) is attenuated ... -
Persistence of Lymphocystis Disease Virus (LCDV) in Seawater
Leiva Rebollo, Rocío; Labella Vera, Alejandro Manuel; Jiménez Valverde, Estefanía; Castro-López, María Dolores; Borrego-García, Juan José (Springer Link, 2020-02-21)
Lymphocystis disease virus (LCDV), the causative agent of lymphocystis disease (LCD), is a waterborne pathogen that uses the external surfaces, including the gills, as portals to gain access to fsh host. However, there ... -
Lymphocystis disease virus (LCDV-Sa), polyomavirus 1 (SaPyV1) and papillomavirus 1 (SaPV1) in samples of Mediterranean gilthead seabream
Labella Vera, Alejandro Manuel; Leiva Rebollo, Rocío; Ali, Aleja; Borrego-García, Juan José (Inter-Research Science Publisher, 2019-01-10)
Lymphocystis disease, caused by the iridovirus lymphocystis disease virus (LCDV), is characterized by the appearance of tumour-like lesions on the skin of affected animals associated with several environmental factors ... -
Identification, resistance to antibiotics and biofilm formation of bacterial strains isolated from a reverse osmosis system of a drinking water treatment plant
Borrego García, Juan José; Labella Vera, Alejandro Manuel; Molero, Rosana; Leiva Rebollo, Rocío; Pérez-Recuerda, Rocío (Elsevier, 2021-02-04)
Membrane processes such as, reverse osmosis (RO), is one option for drinking water treatment where a high product quality is desired. RO membranes are able to effectively remove organic and inorganic compounds and ... -
Immune gene expression in gilthead seabream (Sparus aurata) after Lymphocystis disease virus (LCDV‐Sa) challenge resulting in asymptomatic infection
Leiva Rebollo, Rocío; Labella Vera, Alejandro Manuel; Borrego-García, Juan José; Castro-López, María Dolores (Oxford Academic, 2020-01-01)
Aims: To determine the immune gene expression response of gilthead seabream (Sparus aurata) that is experimentally infected with the lymphocystivirus LCDV-Sa. Methods and Results: Viral DNA and transcripts were detected ... -
Interspecies signalling: Pseudomonas putida efflux pump TtgGHI is activated by indole to increase antibiotic resistance
(Wiley, 2013-12-14)In Gram-negative bacteria, multidrug efflux pumps are responsible for the extrusion of chemicals that are deleterious for growth. Some of these efflux pumps are induced by endogenously produced effectors, while abiotic or ... -
Bacillus subtilis biofilm matrix components target seed oil bodies to promote growth and anti-fungal resistance in melon
(Springer Nature, 2022-06-06)Beneficial microorganisms are used to stimulate the germination of seeds; however, their growth-promoting mechanisms remain largely unexplored. Bacillus subtilis is commonly found in association with different plant organs, ... -
Molecular intraspecific characterization of Photobacterium damselae ssp. damselae strains affecting cultured marine fish
(Wiley, 2010-05-07)In this study, the techniques tested are confirmed as good tools for molecular typing, because they allow discrimination between P. damselae ssp. damselae strains isolated within the same outbreak. In addition, ERIC-PCR and ... -
Toxicity of Photobacterium damselae subsp. damselae strains isolated from new cultured marine fish
(Inter-Research, 2010-10-25)The in vivo and in vitro toxicity of bacterial cells and their extracellular products (ECPs) from 16 strains of Photobacterium damselae subsp. damselae isolated from 7 epizootic outbreaks were evaluated. On the basis of ... -
Efflux pump-deficient mutants as a platform to search for microbes that produce antibiotics
(Wiley, 2015-01-08)Pseudomonas putida DOT-T1E-18 is a strain deficient in the major antibiotic efflux pump (TtgABC) that exhibits an overall increased susceptibility to a wide range of drugs when compared with the wild-type strain. We used ... -
High incidence of antibiotic multi-resistant bacteria in coastal areas dedicated to fish farming
Labella, Alejandro; Gennari, Micol; Ghidini, Valentina; Trento, Ilaria; Manfrin, Amedeo; Borrego-García, Juan José; Lleo, María del Mar[et al.] (Elsevier, 2013-05-15)
Marine bacteria exposed to antibiotics in fish farms can acquire antimicrobial resistance by mobile genetic elements and horizontal gene transfer. A total of 872 autochthonous marine bacterial strains was isolated from ... -
A noninvasive method for time-lapse imaging of microbial interactions and colony dynamics
Molina-Santiago, Carlos; Pearson, John; Berlanga-Clavero, María Victoria; Pérez-Lorente, Alicia Isabel; De-Vicente-Moreno, Antonio; Romero-Hinojosa, Diego Francisco[et al.] (American Society for Microbiology (ASM), 2022-07-05)
Complex interactions between microbial populations can greatly affect the overall properties of a microbial community, sometimes leading to cooperation and mutually beneficial coexistence, or competition and the death or ... -
Co-occurrence of viral and bacterial pathogens in disease outbreaks affecting newly cultured sparid fish
García-Rosado, Esther; Cano, Irene; Martín-Antonio, Beatriz; Labella, Alejandro; Manchado, Manuel; Alonso, María del Carmen; Castro, Dolores; Borrego, Juan José[et al.] (Springer, 2007-09-01)
Several microbial disease outbreaks in farm stocks of newly cultured sparid fish species, such as common seabream, redbanded seabream, and white seabream, were recorded from 2004 to 2006. This study describes the isolation ... -
First isolation of Photobacterium damselae ssp. damselae from cultured redbanded seabream, Pagrus auriga Valenciennes, in Spain
Labella, Alejandro M.; Alonso-Sánchez, María del Carmen; Infante, Carlos; Cardenas, Salvador; López-Romalde, Sonia; Machado, Manuel; Borrego-García, Juan José[et al.] (Blackwell Publishing Ltd, 2006-03-14)
This is the first report of the isolation of P. damselae ssp. damselae from redbanded seabream, a sparid fish newly cultured in southern Spain. A low variability in the biochemical profile among the P. damselae ssp. ...