Listar MD - Artículos por centro "Facultad de Medicina"
Mostrando ítems 1-20 de 76
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A Carboxylesterase 2 Gene Polymorphism as Predictor of Capecitabine on Response and Time to Progression
Ribelles, Nuria; López-Siles, J; Sánchez-Muñoz, Alfonso
; Sánchez, E; González, E; Sánchez, MJ; Carabantes, F; Sánchez- Rovira, P; Márquez, A; Dueñas, R; Sevilla, I; Alba-Conejo, Emilio[et al.] (Bentham Science Publishers Ltd, 2008)
Capecitabine is a drug that requires the consecutive action of three enzymes: carboxylesterase 2 (CES 2), cytidine deaminase (CDD), and thymidine phosphorylase (TP) for transformation into 5-fluorouracil (5FU). The ... -
A microRNA signature associated with early recurrence in breast cancer.
Pérez-Rivas, Luis G.; Jerez-Aragonés, José Manuel; Carmona, Rosario; De Luque, Vanessa; Vicioso-Recio, Luis Prudencio; Claros-Díaz, Manuel Gonzalo; Viguera-Mínguez, Enrique; Pajares, Bella; Sánchez-Muñoz, Alfonso; Ribelles, Nuria; Alba-Conejo, Emilio; Lozano-Castro, José[et al.] (PLOS, 2014-03-14)
Recurrent breast cancer occurring after the initial treatment is associated with poor outcome. A bimodal relapse pattern after surgery for primary tumor has been described with peaks of early and late recurrence occurring ... -
A randomized phase II trial of platinum salts in basal-like breast cancer patients in the neoadjuvant setting. Results from the GEICAM/2006-03, multicenter study
Alba-Conejo, Emilio; Chacón, J. L.; Lluc, A.; Antón, A.; Estévez, L.; Cirauqui, B.; Carrasco, E.; Calvo, L.; Seguí, M.A.; Ribelles, Nuria; Álvarez, R.; Sánchez-Muñoz, Alfonso; Sánchez, R.; Lopez Garcia-Asenjo, J.A.; Rodriguez-Martin, C.; Escudero, M.J.; Albanell, J.[et al.] (Springer, 2012-10)
Abstract Chemotherapy remains as the only systemic treatment option available for basal-like breast cancer (BC) patients. Preclinical models and several phase II studies suggested that platinum salts are active drugs in ... -
Advances and highlights in T and B cell responses to drug antigens
Fernández-Santamaría, Rubén; Ariza Veguillas, Adriana; Fernández-Duarte, Tahía Diana; Céspedes Lagos, José Antonio; Labella, Marina; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa[et al.] (Wiley, 2021-10-07)
The immunological mechanisms involved in drug hypersensitivity reactions (DHRs) are complex, and despite important advances, multiple aspects remain poorly understood. These not fully known aspects are mainly related to ... -
Allergen exposure boosts peripheral Th9 responses in patients with local allergic rhinitis
Palomares, Francisca; Aranda, Carlos José; Saenz de Santa María-García, Rocío; Mayorga Mayorga, Cristobalina; Rondón Segovia, Carmen; Testera Montes, Almudena; Alba-Linero, Carmen; Bentabol-Ramos, Guillermo; Torres-Jaén, María Josefa; Eguiluz-Gracia, Ibón[et al.] (Wiley, 2023)
Key points ∙ Intranasal allergen exposure increases peripheral total Th2 and Th9 cells in patients with local allergic rhinitis (LAR). ∙ Peripheral T-cell response seems dominated by Th9 cells in patients with LAR, ... -
Analysis and evaluation of the operational characteristics of a new photodynamic therapy device
Navarrete-de-Gálvez, Enrique; Aguilera-Arjona, José; Fonda Pascual, Pablo; De-Gálvez-Aranda, María Victoria; Andrés-Díaz, José Ramón; Vidal Asensi, Santiago; Herrera-Acosta, Enrique; Gago-Calderón, Alfonso[et al.] (Elsevier, 2022)
One of the key aspects of photodynamic therapy is the light source that is used to irradiate the lesion to be treated. The devices used must ensure that their emission spectrum matches the absorption spectrum of the ... -
Assessment of Procalcitonin as a Diagnostic and Prognostic Marker in Patients with Solid Tumors and Febrile Neutropenia
Jimeno, Antonio; García-Velasco, Adelaida; del Val, Olga; González-Billalabeitia, Enrique; Hernando, Susana; Hernández, Rosario; Sánchez-Muñoz, Alfonso; López-Martın, Ana; Durán, Ignacio; Robles, Luis; Corté-Funes, Hernán; Paz-Ares, Luis[et al.] (Wiley InterScience, 2004-03)
Cancer patients with fever and neutropenia currently are assessed on clinical grounds only. The current study prospectively evaluated the efficacy of baseline procalcitonin (PCT) in the detection of bacteremia and in the ... -
Association of Circular RNA and Long Non-Coding RNA Dysregulation with the Clinical Response to Immune Checkpoint Blockade in Cutaneous Metastatic Melanoma.
Oliver, Javier; Onieva Zafra, Juan Luis; Garrido-Barros, María; Berciano-Guerrero, Miguel Ángel; Sánchez-Muñoz, Alfonso; Lozano, María José; Farngren, Angela; Álvarez-Pérez, Martina; Martínez-Gálvez, Beatriz; Pérez-Ruiz, Elisabeth; Alba-Conejo, Emilio; Cobo Dols, Manuel Ángel; Rueda-Domínguez, Antonio; Barragán, Isabel[et al.] (MDPI, 2022)
Cutaneous melanoma (CM) is the most lethal form of skin cancer if it becomes metastatic, where treatment options and survival chances decrease dramatically. Immunotherapy treatments based on the immunologic checkpoint ... -
Basophil Activation Test Utility as a Diagnostic Tool in LTP Allergy
Cañas, José Antonio; Pérez-Sánchez, Natalia Isabel; Palomares, Francisca; Molina, Ana; Bartra, Joan; Torres-Jaén, María Josefa; Gómez, Francisca; Mayorga Mayorga, Cristobalina[et al.] (IOAP-MPDI, 2022-04-29)
Plant-food allergy is an increasing problem, with nonspecific lipid transfer proteins (nsLTPs) triggering mild/severe reactions. Pru p 3 is the major sensitizer in LTP food allergy (FA). However, in vivo and in vitro ... -
Beneficial Effects of Essential Oils from the Mediterranean Diet on Gut Microbiota and Their Metabolites in Ischemic Heart Disease and Type-2 Diabetes Mellitus
Sánchez-Quintero, María José; Delgado, Josué; Medina-Vera, Dina; Becerra-Muñoz, Víctor Manuel; Queipo-Ortuño, María Isabel; Estévez, Mario; Plaza-Andrades, Isaac; Rodríguez Capitán, Jorge; Sánchez, Pedro L.; Crespo-Leiro, María G.; Jiménez-Navarro, Manuel Francisco; Pavón-Morón, Francisco Javier[et al.] (IOAP-MPDI, 2022-11-03)
Ischemic heart disease (IHD) and type-2 diabetes mellitus (T2DM) remain major health problems worldwide and commonly coexist in individuals. Gut microbial metabolites, such as trimethylamine N-oxide (TMAO) and short-chain ... -
Bevacizumab plus low-dose metronomic oral cyclophosphamide in heavily pretreated patients with recurrent ovarian cancer
Sánchez-Muñoz, Alfonso; Mendiola, César; Pérez-Ruiz, Elisabeth; Rodríguez-Sánchez, César A.; Jurado, José Miguel; Alonso-Carrión, Lorenzo Javier; Ghanem, Ismael; Velasco, Guillermo de; Quero-Blanco, Cristina; Alba-Conejo, Emilio[et al.] (KARGER, 2010-11)
Aim: To retrospectively assess the efficacy and safety of bevacizumab plus low-dose metronomic oral cyclophosphamide in heavily pretreated patients with recurrent ovarian cancer. Patients and Methods: Patients with recurrent ... -
Biomarkers predicting the controller dose of omalizumab in patients with chronic spontaneous urticaria
Zubiaga- Fernandez, L.; Testera Montes, Almudena; Rondon, C.; Perez-Sanchez, N.; Gomez- Perez, F.; Vega-Chicote, J. M.; Bartra, Joan; Ferrer, M.; Eguiluz-Gracia, Ibón; Torres-Jaén, María Josefa[et al.] (Wiley, 2024-02-11)
Background Clinical trials showed the efficacy of 300 mg/4 weeks of omalizumab (OMA) during 6 months in patients with severe chronic spontaneous urticaria (CSU). Nevertheless, in real life, many patients require higher ... -
Brain areas interconnected to ventral pathway circuitsare independently able to induce enhancement in objectrecognition memory and cause reversal in object recognitionmemory deficit.
Masmudi-Martin, Mariam; Navarro-Lobato, Irene; López-Aranda, Manuel Francisco; Quirós-Ortega, María Elena; Carretero-Rey, Marta; García-Garrido, María F.; López-Téllez, Juan Félix; Jiménez Recuerda, Inmaculada; Muñoz-de-León-López, Cristina; Khan, Zafaruddin[et al.] (Wiley, 2024)
Ventral pathway circuits are constituted by the interconnected brain areas that are distributed throughout the brain. These brain circuits are primarily involved in processing of object related information in brain. However, ... -
Brain structural and functional correlates of the heterogenous progression of mixed transcortical aphasia
López-Barroso, Diana; Paredes-Pacheco, José; Torres-Prioris, María José; Dávila-Arias, María Guadalupe; Berthier-Torres, Marcelo Luis (Springer, 2023)
Mixed transcortical aphasia (MTCA) is characterized by non-fluent speech and comprehension deficits coexisting with preserved repetition. MTCA may evolve to less severe variants of aphasias or even to full language recovery. ... -
Un caso de hipocolesterolemia a estudio
Camacho, Ana; Ariza-Corbo, María José; Amigó, Nuria; Macías Guillén, Patricia; Sánchez-Chaparro, Miguel Ángel; Valdivielso-Felices, Pedro[et al.] (Elsevier, 2023)
Las hipocolesterolemias primarias (o hipobetalipoproteinemias) constituyen un trastorno infrecuente del metabolismo de las lipoproteínas que pueden obedecer a una predisposición poligénica o a una enfermedad monogénica. ... -
Changing patterns in the epidemiology of drug allergy
Doña, Inmaculada; Torres-Jaén, María Josefa; Gulfem, Celik; Phillips, Elizabeth; Kase Tanno, Luciana; Castells, Mariana[et al.] (Wiley, 2023-12-12)
Drug allergy (DA) remains a complex and unaddressed problem worldwide that often deprives patients of optimal medication choices and places them at risk for life-threatening reactions. Underdiagnosis and overdiagnosis are ... -
Clinical and epidemiologic characteristics of hospitalized oncological patients with hypercalcemia: a longitudinal, multicenter study
Ropero-Luis, Guillermo; Sanz-Cánovas, Jaime; López-Sampalo, Almudena; Ruiz Cantero, Alberto; Gómez-Huelgas, Ricardo (2024-07-23)
Background There are few studies that have analyzed the characteristics of hypercalcemia in hospitalized oncological patients. Our objectives were to describe the clinical characteristics of hospitalized patients with ... -
Controversias sobre los riesgos pro-carcinogenicos asociados al uso de lamparas UV polimerizadoras para el esmaltado permanente de uñas
Aguilera-Arjona, José; Bosch-García, Ricardo Juan; De-Gálvez-Aranda, María Victoria (Elsevier, 2023-12-27)
Antecedentes: Recientemente se ha suscitado una polémica por el potencial pro-carcinogénico de la exposición a lámparas de rayos UVA necesarias para el esmaltado permanente de uñas. La entrada de nuevos dispositivos de ... -
Correlation between UV Index, Temperature and Humidity with Respect to Incidence and Severity of COVID 19 in Spain
Pérez-Gilaberte, Juan Blas; Martín-Iranzo, Natalia; Aguilera-Arjona, José; Almenara-Blasco, Manuel; De-Gálvez-Aranda, María Victoria; Gilaberte, Yolanda[et al.] (IOAP-MDPI, 2023-01-20)
Background: Various studies support the inverse correlation between solar exposure and Coronavirus SARS-CoV-2 infection. In Spain, from the Canary Islands to the northern part of the country, the global incidence of COVID-19 ...