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An algorithm for the diagnosis of beta-lactam allergy, 2024 update
(Wiley, 2024-10) -
The topical application of different galenic formulations can alter the thermographic images of skin: Limitations for public thermal screening on infection control situations.
(Elsevier, 2023)En época de COVID y bajo la perspectiva del control de tráfico de personas, si la aplicación de fórmulas tópicas como cosméticos o protectores solares podría afectar a las lecturas termográficas cutáneas en situación del ... -
AMPA receptors in synaptic plasticity, memory function, and brain diseases
(Springer Nature, 2025-01-22)Tetrameric AMPA-type ionotropic glutamate receptors are primary transducers of fast excitatory synaptic transmission in the central nervous system, and their properties and abundance at the synaptic surface are crucial ... -
Olfactory Dysfunction as a Biomarker for Early Diagnosis of Cognitive Impairment in Patients With Type 2 Diabetes: A Systematic Review
(Wiley, 2024-12)Background: Olfactory dysfunction and cognitive impairment (CI) have been associated with Type 2 diabetes (T2DM), but the mechanisms underlying this association are broadly unknown. This systematic review tends to investigate ... -
Effect of an intensive lifestyle intervention on cystatin C–based kidney function in adults with overweight and obesity: From the PREDIMED-Plus trial
(Wiley, 2024)In older adults with overweight/obesity and metabolic syndrome, the PREDIMED-Plus intervention may be an optimal approach to pre-serve kidney function. -
Effect of Self-Chosen Music in Alleviating the Burden on Family Caregivers of Patients with Advanced Cancer: A Randomised Controlled Trial
(MDPI, 2023-03-06)The experience of caregiver burden among family members of patients with advanced cancer is a common problem. The aim of this study was to determine whether the burden may be alleviated by means of a therapeutic approach ... -
Early Diagnosis of Oral Cancer and Lesions in Fanconi Anemia Patients: A Prospective and Longitudinal Study Using Saliva and Plasma
(MDPI, 2023-03-21)Fanconi anemia (FA) patients display an exacerbated risk of oral squamous cell carcinoma (OSCC) and oral potentially malignant lesions (OPMLs) at early ages. As patients have defects in their DNA repair mechanisms, ... -
Recombinant soluble type I interferon receptor exerts antiviral activity by inducing proteins related to autophagy
(Elsevier, 2024)The soluble type I IFN receptor (sIFNAR2) is produced by alternative splicing and is present in body fluids. Although it can modulate IFN-ß activity, its biological role remains unknown. Methods: An in-silico study was ... -
Effects of testosterone and metformin on the GlycanAge index of biological age and the composition of the IgG glycome
(Springer, 2024)With aging, the body’s ability to maintain regular functions declines, increasing susceptibility to age-related diseases. Therapeutic interventions targeting the underlying biological changes of aging hold promise for ... -
Brain areas interconnected to ventral pathway circuitsare independently able to induce enhancement in objectrecognition memory and cause reversal in object recognitionmemory deficit.
(Wiley, 2024)Ventral pathway circuits are constituted by the interconnected brain areas that are distributed throughout the brain. These brain circuits are primarily involved in processing of object related information in brain. However, ... -
Medical algorithm: Diagnosis and treatment of nonsteroidal antiinflammatory drugs hypersensitivity
(Wiley, 2020)Diagnosis in suspected hypersensitivity reactions to nonsteroidal anti-inflammatory drugs (NSAIDs) is complex as different mechanisms are involved: specific (selective responders, SRs) and nonspecific immunologically ... -
Methods for causality assessment of idiosyncratic drug-induced liver injury
(Wiley, 2024)The diagnosis of idiosyncratic drug-induced liver injury (DILI) is a challenging task due to the lack of specific features or definitive diagnostic tools. A minimum of clinical and pharmacological information is required, ... -
Clinical and epidemiologic characteristics of hospitalized oncological patients with hypercalcemia: a longitudinal, multicenter study
(2024-07-23)Background There are few studies that have analyzed the characteristics of hypercalcemia in hospitalized oncological patients. Our objectives were to describe the clinical characteristics of hospitalized patients with ... -
Type 1 diabetes-related distress: Current implications in care
(Elsevier, 2024)Type 1 diabetes (T1D) is a complex chronic disease associated with major health and economic consequences, also involving important issues in the psychosocial sphere. In this regard, T1D-related distress, defined as the ... -
Genomic variants association with selective hypersensitivityreactions to amoxicillin and clavulanic acid
(Wiley, 2024-06-29)In summary, there are rare variants found in our patients that could be related to the development of AX or CLV- induced IDHRs. Interestingly, some of these rare variants could be associated with selective response to ... -
Working with companies that manufacture breastmilk substitutes: An EAACI position paper
(Wiley, 2024-05)Breastmilk is the optimal source of nutrition for infants and should ideally be provided exclusively for the first 6 months of life, and alongside complementary food until 2 years of life. However, there are circumstances ... -
Randomized phase II study of fulvestrant plus palbociclib or placebo in endocrine-sensitive, hormone receptor-positive/HER2-advanced breast cancer: GEICAM/2014-12 (FLIPPER).
(Elsevier, 2022)Background: The potential benefit of adding palbociclib to fulvestrant as first-line treatment in hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative endocrine-sensitive advanced breast ... -
Treatment and outcome of patients with stage IS testicular cancer: a retrospective study from the Spanish Germ Cell Cancer Group.
(Lippincott, Williams & Wilkins, 2019)Stage IS testicular cancer is defined by the persistence of elevated serum tumor markers, including α-fetoprotein and/or β-human chorionic gonadotropin, after orchiectomy without radiological evidence of metastatic disease. ... -
Male breast cancer: correlation between immunohistochemical subtyping and PAM50 intrinsic subtypes, and the subsequent clinical outcomes
(Elsevier, 2018-02)Male breast cancer is a rare disease that is still poorly understood. It is mainly classified by immunohistochemistry as a luminal disease. In this study, we assess for the first time the correlation between molecular ... -
Different Pathological Complete Response Rates According to PAM50 Subtype in HER2+ Breast Cancer Patients Treated With Neoadjuvant Pertuzumab/Trastuzumab vs. Trastuzumab Plus Standard Chemotherapy: An Analysis of Real-World Data.
(Frontiers Media, 2019)Double blockade with pertuzumab and trastuzumab combined with chemotherapy is the standard neoadjuvant treatment for HER2-positive early breast cancer. Data derived from clinical trials indicates that the response rates ...