Listar IBIMA. Instituto de Investigación Biomédica de Málaga por título
Mostrando ítems 1-20 de 43
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8-oxoguanine DNA glycosylase 1 upregulation as a risk factor for obesity and colorectal cancer
Pilo, Jesús; García-Flores, Libia Alejandra; Clemente-Postigo, María Mercedes
; Arranz-Salas, Isabel María; Alcaide, Julia; Ramos-Fernandez, Maria; Lozano-Castro, José; Boughanem Lakhal, Hatim; Kompella, Pallavi; Macías-González, Manuel[et al.] (MDPI, 2023-03-13)
DNA damage has been extensively studied as a potentially helpful tool in assessing and preventing cancer, having been widely associated with the deregulation of DNA damage repair (DDR) genes and with an increased risk of ... -
Active and Assisted Living, a Practice for the Ageing Population and People with Cognitive Disabilities: An Architectural Perspective.
Quesada-García, Santiago; Valero-Flores, Pablo; Lozano-Gómez, María (MDPI, 2023-05-19)
The current digital revolution is causing a paradigm shift encompassing all environments in which human beings conduct their daily activities. Technology is starting to govern the world, gradually modifying not only ... -
Antipsychotic Medication Influences the Discriminative Value of Acylethanolamides as Biomarkers of Substance Use Disorder.
Herrera-Imbroda, Jesús; Flores-López, María; Requena-Ocaña, Nerea; Araos Gómez, Pedro Fernando; Ropero, Jessica; García-Marchena, Nuria; Bordallo Aragón, Antonio; Suárez-Pérez, Juan; Pavón-Morón, Francisco Javier; Serrano, Antonia; Mayoral Cleries, Fermín; Rodriguez-de-Fonseca, Fernando[et al.] (MDPI, 2023-05-27)
Plasma acylethanolamides (NAEs), including the endocannabinoid anandamide (AEA), have been proposed as circulating biomarkers of substance use disorders. However, the concentration of these lipid transmitters might be ... -
Anxiety associated with palatable food withdrawal is reversed by the selective FAAH inhibitor PF-3845: A regional analysis of the contribution of endocannabinoid signaling machinery
(Wiley, 2023)Objective: Consumption of energy-dense palatable "comfort" food can alleviate stress and negative emotions, while abrupt withdrawal from a palatable diet can worsen these symptoms, causing difficulties with adherence to ... -
Association between Cardiovascular Health, C-Reactive Protein, and Comorbidities in Spanish Urban-Dwelling Overweight/Obese Hypertensive Patients.
Armas-Padrón, Ana María; Sicilia-Sosvilla, Miriam; Ruiz Esteban, Pedro; Torres, Armando; Hernández-Marrero, Domingo (MDPI, 2023-07-13)
The relationship between poorer cardiovascular health metrics (CVHM) plus low-grade inflammation (LGI) and hypertension-mediated organ damage (HMOD) and hypertension-related comorbidities (HRC) in hypertensive populations ... -
Basophil activation test is a complementary tool in the diagnosis of immediate reactions to platinum salts and taxanes
(Wiley, 2024)Background Delabelling pathways offer confirmatory diagnosis and can prevent unnecessary second-line therapies or drug desensitization procedures after chemotherapeutic hypersensitivity reactions (CHT-HSRs). However, these ... -
Biomarkers of immediate drug hypersensitivity
Mayorga Mayorga, Cristobalina; Ariza, Adriana; Muñoz-Cano, Rosa; Sabato, Vito; Doña, Inmaculada; Torres-Jaén, María Josefa[et al.] (Wiley, 2023-11-10)
Immediate drug hypersensitivity reactions (IDHRs) are a burden for patients and the health systems. This problem increases when taking into account that only a small proportion of patients initially labelled as allergic ... -
Combined Body Mass Index and Waist-to-Height Ratio and Its Association with Lifestyle and Health Factors among Spanish Children: The PASOS Study
Bibiloni, María del Mar; Gallardo-Alfaro, Laura; Gómez, Santiago F.; Warnberg, Julia; Osés-Recalde, Maddi; González-Gross, Marcela; Gusi, Narcís; Aznar, Susana; Marín-Cascales, Elena; González-Valeiro, Miguel Ángel; Serra-Majem, Lluís; Terrados, Nicolás; Segú, Marta; Lassale, Camille; Homs, Clara; Benavente Marín, Juan Carlos; Labayen, Idoia; Zapico, Augusto G.; Sánchez-Gómez, Jesús; Jiménez-Zazo, Fabio; Alcaraz, Pedro E; Sevilla-Sánchez, Marta; Herrera-Ramos, Estefanía; Pulgar-Muñoz, Susana; Sistac-Sorigué, Clara; Schröder, Helmut; Bouzas, Cristina; Tur, Josep A.[et al.] (IOAP-MDPI, 2022-01-06)
Antecedentes y objetivos: La Organización Mundial de la Salud recomendó la medición simultánea del índice de masa corporal (IMC) y la circunferencia de la cintura (CC) y sugirió el uso conjunto para predecir los riesgos ... -
Cross Sectional and Case-Control Study to Assess Time Trend, Gender Differences and Factors Associated with Physical Activity among Adults with Diabetes: Analysis of the European Health Interview Surveys for Spain (2014 & 2020)
Llamas-Sáez, Carlos; Saez-Vaquero, Teresa; Jiménez-García, Rodrigo; López de Andrés, Ana; Carabantes-Alarcón, David; Zamorano-León, Jose J.; Cuadrado-Corrales, Natividad; Pérez-Farinós, José Napoleón; Warnberg, Julia[et al.] (MDPI, 2023-04-22)
Background: We aim to assess the time trend from 2014 to 2020 in the prevalence of physical activity (PA), identify gender differences and sociodemographic and health-related factors associated with PA among people with ... -
Effects of exercise timing on metabolic health
Martínez-Montoro, José Ignacio; Benítez-Porres, Javier; Tinahones-Madueño, Francisco José; Ortega-Gómez, Almudena; Murri, Mora (Wiley, 2023)
The increasing prevalence of metabolic syndrome is associated with major health and socioeconomic consequences. Currently, physical exercise, together with dietary interventions, is the mainstay of the treatment of obesity ... -
Effects of Music on the Quality of Life of Family Caregivers of Terminal Cancer Patients: A Randomised Controlled Trial
Valero-Cantero, Inmaculada; Casals, Cristina; Espinar-Toledo, Milagrosa; Barón-López, Francisco Javier; García-Agua-Soler, Nuria; Vázquez-Sánchez, María Ángeles[et al.] (MDPI, 2023-07-09)
The aim of this study was to investigate the effects of listening to self-chosen music on the quality of life of family caregivers of cancer patients receiving palliative home care. A total of 82 family caregivers were ... -
End of life in patients attended by pediatric palliative care teams: what factors influence the place of death and compliance with family preferences?
Peláez-Cantero, María José; Morales-Asencio, José Miguel; Navarro-Mingorance, Álvaro; Madrid-Rodríguez, Aurora; Tavera-Tolmo, Ángela; Escobosa-Sánchez, Olga María; Martino-Alba, Ricardo[et al.] (Springer, 2023)
Each year, more than 8 million children worldwide require specialized palliative care, yet there is little evidence available in pediatrics on the characteristics of the end of life in this context. Our aim is to analyze ... -
Epigenetic changes in the metabolically healthy obese: A case-control versus a prospective study
(Wiley, 2022-03-28)Obesity has become a worldwide health problem, in which latest statistics reported an increased trend over the last years. Accordingly, long-term obesity is involved in an increased risk of developing several metabolic ... -
Evaluation of Gait Parameters on Subjects with Hallux Limitus Using an Optogait Sensor System: A Case–Control Study
(MDPI, 2023-08-23)Background and Objetives: The foot is a part of the body’s kinetic chain and needs to be efficient during the entire gait cycle. Electronic Sensor Gait analysis is useful and an important tool within the area of podiatry ... -
Flow-based basophil activation test in immediate drug hypersensitivity. An EAACI task force position paper
Mayorga Mayorga, Cristobalina; Çelik, G.E.; Pascal, M.; Hoffmann, H.J.; Eberlein, B.; Torres-Jaén, María Josefa; Brockow, K.; Garvey, L.H.; Barbaud, A.; Madrigal-Burgaleta, R.; Caubet, J.C.; Ebo, D.G.[et al.] (Wiley, 2023-11-13)
Diagnosing immediate drug hypersensitivity reactions (IDHRs) can pose a significant challenge and there is an urgent need for safe and reliable tests. Evidence has emerged that the basophil activation test (BAT), an in ... -
Fluorometric Quantification of Total Cell-Free DNA as a Prognostic Biomarker in Non-Small-Cell Lung Cancer Patients Treated with Immune Checkpoint Blockade.
Oliver, Javier; Onieva Zafra, Juan Luis; Garrido-Barros, María; Cobo Dols, Manuel Ángel; Martínez-Gálvez, Beatriz; García-Pelícano, Ana Isabel; Dubbelman-Vizcaíno, Jaime; Benítez, Jose Carlos; Zafra-Martín, Juan; Cantero-González, Alejandra; Pérez-Ruiz, Elisabeth; Rueda-Domínguez, Antonio; Barragán, Isabel[et al.] (MDPI, 2023-06-26)
The present study aimed to investigate the potential of basal cell-free fluorometric DNA (cfDNA) quantification as a prognostic biomarker in advanced non-small cell lung cancer (NSCLC) patients treated with an Immune ... -
Genetically Engineered Triple MAPT-Mutant Human-Induced Pluripotent Stem Cells (N279K, P301L, and E10+16 Mutations) Exhibit Impairments in Mitochondrial Bioenergetics and Dynamics.
Szabo, Leonora; Grimm, Amandine; García-León, Juan Antonio; Verfaillie, Catherine M.; Eckert, Anne (MDPI, 2023-05-13)
Pathological abnormalities in the tau protein give rise to a variety of neurodegenerative diseases, conjointly termed tauopathies. Several tau mutations have been identified in the tau-encoding gene MAPT, affecting either ... -
Global subjective assessment and mini nutritional assessment short form better predict mortality than GLIM malnutrition criteria in elderly patients with hip fracture
Sánchez-Torralvo, Francisco José; Pérez-del-Río, Verónica; García-Olivares, María; Porras, Nuria; Abuín-Fernández, José; Bravo-Bardají, Manuel Francisco; García-de-Quevedo-Puerta, David; Olveira-Fuster, Gabriel María[et al.] (MDPI, 2023-04-10)
The objective of our study is to determine the prevalence of malnutrition in elderly patients with fragility hip fractures through different diagnostic tools and to determine which nutritional assessment tool better predicts ... -
Hepatic and serum branched-chain fatty acid profile in patients with nonalcoholic fatty liver disease: A case–control study
Martínez-Montoro, José Ignacio; Nuñez-Sanchez, María Ángeles; Martinez-Sanchez, María Antonia; Balaguer-Román, Andrés; Fernández-Ruiz, Virginia E.; Ferrer-Gómez, Mercedes; Sledzinski, Tomasz; Frutos, María Dolores; Fernández-García, José Carlos; Mika, Adriana; Ramos-Molina, Bruno[et al.] (Wiley, 2023)
Objective Alterations in the hepatic lipidome are a crucial factor involved in the pathophysiology of nonalcoholic fatty liver disease (NAFLD). The aim of this study was to evaluate the serum and hepatic profile of ... -
Immune Mechanism of Epileptogenesis and Related Therapeutic Strategies
Aguilar-Castillo, María José; Cabezudo-García, Pablo; Ciano-Petersen, Nicolas Lundahl; García-Martín, Guillermina; Marín-Gracia, Marta; Estivill-Torrús, Guillermo; Serrano-Castro, Pedro Jesús[et al.] (IOAP-MPDI, 2022-03-19)
Immunologic and neuroinflammatory pathways have been found to play a major role in the pathogenesis of many neurological disorders such as epilepsy, proposing the use of novel therapeutic strategies. In the era of personalized ...