Listar FHEFD - Artículos por título
Mostrando ítems 1-20 de 136
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A new pharmacological strategy against treatment-resistant depression
Pineda-Gomez, Juan Pedro; Millón-Peñuela, Carmelo
; Cantero García, Noelia; Flores, Marta; Ladrón de Guevara-Miranda, David; Flores-Burgess, Antonio; Díaz-Cabiale, Zaida[et al.] (Elsevier, 2024)
Major depressive disorder affects more than 50 million people in the world. However, 50% of patients don’t respond to two or more drugs or psychotherapeutic treatments, named treatment-resistant depression (TRD). In this ... -
A Novel Human TGF-β1 Fusion Protein in Combination with rhBMP-2 Increases Chondro-Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells
Claros-Gil, Silvia; Rico-Llanos, Gustavo Adolfo; Becerra-Ratia, José; Andrades-Gómez, José Antonio (MDPI, 2014)
Transforming growth factor-beta (TGF-β) is involved in processes related to the differentiation and maturation of osteoprogenitor cells into osteoblasts. Rat bone marrow (BM) cells were cultured in a collagen-gel containing ... -
A randomized open-labeled study to examine the effects of creatine monohydrate and combined training on jump and scoring performance in young basketball players
Vargas-Molina, Salvador; García-Sillero, Manuel; Kreider, Richard B.; Salinas, Enrique; Petro, Jorge Luis; Benítez-Porres, Javier; Bonilla, Diego A.[et al.] (Taylor & Francis Group, 2022-08-08)
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A Role for Galanin N-Terminal Fragment (1–15) in Anxiety- and Depression-Related Behaviors in Rats.
Millón-Peñuela, Carmelo; Flores-Burgess, Antonio; Narváez-Peláez, Manuel; Borroto Escuela, Dasiel Óscar; Santín-Núñez, Luis Javier; Parrado-Romero, Concepción; Narvaez, Jose Angel; Fuxe, Kjell; Díaz-Cabiale, Zaida[et al.] (Oxford Academic, 2015-02-16)
Galanin (GAL) plays a role in mood regulation. In this study we analyzed the action of the active N-terminal fragment [GAL(1–15)] in anxiety- and depression-related behavioral tests in rats. Methods: The effect of ... -
A5 region modulation of the cardiorespiratory responses evoked from parabrachial cell bodies in the anaesthetised rat
Dawid-Milner, Marc Stefan; Lara-Muñoz, José Pablo; López de Miguel, M Pilar; López-González, Manuel Víctor; Spyer, KM; González-Barón, Salvador[et al.] (Elsevier, 2003)
We have examined the importance of the A5 region modulating cardiorespiratory responses evoked from the parabrachial complex (PB) in spontaneously breathing rats. Cardiorespiratory changes were analyzed in response to ... -
Abnormal cannabidiol ameliorates inflammation preserving pancreatic beta cells in mouse models of experimental type 1 diabetes and beta cell damage
González-Mariscal, Isabel; Pozo-Morales, Macarena; Romero-Zerbo, Silvana Yanina; Espinosa-Jiménez, Vanesa; Escamilla-Sánchez, Alejandro; Sánchez-Salido, Lourdes; Cobo-Vuilleumier, Nadia; Gauthier, Benoit R.; Bermúdez Silva, Francisco Javier[et al.] (Elsevier, 2021-12-03)
The atypical cannabinoid Abn-CBD improves the inflammatory status in preclinical models of several pathologies, including autoimmune diseases. However, its potential for modulating inflammation in autoimmune type 1 diabetes ... -
Acute Effects of Blood Flow Restriction Training on Movement Velocity and Neuromuscular Signal during the Back Squat Exercise
García-Sillero, Manuel; Maroto-Izquierdo, Sergio; Galván-García, María; Benítez-Porres, Javier; Vargas-Molina, Salvador; Jurado‑Castro, José Manuel[et al.] (MDPI, 2023-07-21)
The aim of this study was to verify the effects of blood flow restriction on movement velocity and muscle activity during the back squat exercise. Methods: Twenty-four university students participated in this study. In ... -
Age and training-related changes on body composition and fitness in male amateur cyclists
Alvero-Cruz, José Ramón; García-Romero, Jerónimo; Ordoñez, Francisco Javier; Mongin, Denis; Correas-Gómez, Lorena; Nikolaidis, Pantelis T.; Knetchle, Beat[et al.] (Multidisciplinary Digital Publishing Institute (MDPI), 2022-01-01)
Master athletes are considered as a model of healthy aging because they can limit the age-related decline of physiological abilities compared to sedentary individuals. The main objective of this study is to analyze age-related ... -
Alpha-tocopherol protects against oxidative stress in the fragile X knockout mouse: an experimental therapeutic approach for the Fmr1 deficiency.
De Diego‑Otero, Yolanda; Romero-Zerbo, Silvana Yanina; El-Bekay, Rajaa; Decara, Juan; Sánchez-Salido, Lourdes; Rodriguez-de-Fonseca, Fernando; Del Arco-Herrera, Ignacio[et al.] (Springer Nature, 2009)
Fragile X syndrome is the most common genetic cause of mental disability. The mechanisms underlying the pathogenesis remain unclear and specific treatments are still under development. Previous studies have proposed an ... -
Antisense Oligonucleotides and Magnetic Nanoparticles for Targeted Diagnostic and Cancer Treatment.
Ruiz-Gómez, Miguel José; López-Díaz, Beatriz; Mercado-Sáenz, Silvia; Sendra-Portero, Francisco (MedCrave, 2017-05-31)
The resistance of tumors to therapeutic intervention is a major problem in the efficacy of treatments. A recent strategy to overcome this problem proposes the association of antitumor drugs with colloidal nanoparticles. ... -
Apoptosis of peritoneal leucocytes during early stages of Fasciola hepatica infections in sheep
Escamilla-Sánchez, Alejandro; Pérez-Caballero, Raúl; Zafra, Rafael; Bautista, María José; Pacheco Luque, Isabel; Ruiz-Campillo, María Teresa; Martínez-Cruz, Setefilla; Martinez Moreno, Álvaro; Molina-Hernández, Verónica; Pérez, José[et al.] (Elsevier B.V., 2017-04)
Several immunomodulatory properties have been described in Fasciola hepatica infections. Apoptosis has been shown to be an effective mechanism to avoid the immune response in helminth infections. The aim of the present ... -
Autologous Human-Derived Bone Marrow Cells Exposed to a Novel TGF-β1 Fusion Protein for the Treatment of Critically Sized Tibial Defect.
Becerra-Ratia, José; Guerado-Parra, Enrique; Claros-Gil, Silvia; Alonso, Mónica; Bertrand, María L; González Plata, Carlos; Andrades-Gómez, José Antonio[et al.] (Taylor & Francis, 2006)
We report the first clinical case of transplantation of autologous bone marrow-derived cells in vitro exposed to a novel recombinant human transforming growth factor (rhTGF)-β1 fusion protein bearing a collagen-binding ... -
Bilateral brain reorganization with memantine and constraint-induced aphasia therapy in chronic post-stroke aphasia: An ERP study
Barbancho-Fernández, Miguel Ángel; Berthier-Torres, Marcelo Luis; Navas-Sánchez, Patricia; Dávila-Arias, María Guadalupe; Green-Heredia, Cristina; García-Alberca, J.M.; Ruiz-Cruces, Rafael; López-González, Manuel Víctor; Dawid-Milner, Marc Stefan; Pulvermüller, Friedemann; Lara-Muñoz, José Pablo[et al.] (Elsevier, 2015)
Changes in ERP (P100 and N400) and root mean square (RMS) were obtained during a silent reading task in 28 patients with chronic post-stroke aphasia in a randomized, double-blind, placebo-controlled trial of both memantine ... -
Blood vessels guide Schwann cell migration in the adult demyelinated CNS through Eph/ephrin signaling
(Springer Link, 2019)Schwann cells (SC) enter the central nervous system (CNS) in pathophysiological conditions. However, how SC invade the CNS to remyelinate central axons remains undetermined. We studied SC migratory behavior ex vivo and ... -
Cambios de la composición corporal tras un periodo de desentrenamiento deportivo
Alvero-Cruz, José Ramón; Ronconi, Mauro; García-Romero, Jerónimo; Carrillo-de-Albornoz, Margarita; Jimenez Lopez, Manuel; Correas-Gómez, Lorena; Álvarez-Carnero, Elvis[et al.] (ARÁN, 2016-12)
Introducción: la influencia del ejercicio físico en sujetos entrenados tiene efectos beneficiosos en la condición física y la composición corporal. Sin embargo, el desentrenamiento tiene un efecto desfavorable en todas ... -
Cannabinoids, eating behaviour, and energy homeostasis
Romero-Zerbo, Silvana Yanina; Bermúdez Silva, Francisco Javier (John Wiley & Sons, 2014)
Soon after the discovery of cannabis by western societies, its psychotropic effects overshadowed its medical benefits. How-ever, investigation into the molecular action of the main constituents of cannabis has led to the ... -
Cellular aging: theories and technological influence
Mercado-Sáenz, Silvia; Ruiz-Gómez, Miguel José; Morales-Moreno, Francisco; Martínez Morillo, Manuel (Scielo Brazil, 2010-12-02)
The aim of this article was to review the factors that influence the aging, relationship of aging with the biological rhythms and new technologies as well as the main theories to explain the aging, and to analysis the ... -
Challenging the top player: A preliminary study on testosterone response to an official chess tournament
Mendoza Torrico, Guillermo; Jimenez Lopez, Manuel; García-Romero, Jerónimo; Garcia Bastida, Jorge; Rivilla, Iván; Carrillo-de-Albornoz, Margarita; Barón-López, Francisco Javier; Benítez-Porres, Javier; Alvero-Cruz, José Ramón[et al.] (Multidisciplinary Digital Publishing Institute (MDPI), 2020-02-02)
According to the Challenge Hypothesis, high levels of testosterone (T) are associated with status-seeking behaviors, especially in competitive situations. However, there have not been many studies about rivals’ social ... -
Characterization of adult stem/progenitor cell populations from bone marrow in a three-dimensional collagen gel culture system.
Claros-Gil, Silvia; Rodríguez-Losada, Noela; Cruz, Encarnación; Guerado-Parra, Enrique; Becerra-Ratia, José; Andrades-Gómez, José Antonio[et al.] (Sage Publications, 2012-09-01)
Stem cell transplantation therapy using mesenchymal stem cells (MSCs) is considered a useful strategy. Although MSCs are commonly isolated by exploiting their plastic adherence, several studies have suggested that there ...