Listar Fisiología Humana, Histología Humana, Anatomía Patológica y Educación Física y Deportiva - (FHEFD) por centro "Facultad de Ciencias"
Mostrando ítems 1-15 de 15
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A Novel Human TGF-β1 Fusion Protein in Combination with rhBMP-2 Increases Chondro-Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells
Claros-Gil, Silvia
; Rico-Llanos, Gustavo Adolfo; Becerra-Ratia, José; Andrades-Gómez, José Antonio (MDPI, 2014)
Transforming growth factor-beta (TGF-β) is involved in processes related to the differentiation and maturation of osteoprogenitor cells into osteoblasts. Rat bone marrow (BM) cells were cultured in a collagen-gel containing ... -
Autologous Human-Derived Bone Marrow Cells Exposed to a Novel TGF-β1 Fusion Protein for the Treatment of Critically Sized Tibial Defect.
Becerra-Ratia, José; Guerado-Parra, Enrique; Claros-Gil, Silvia; Alonso, Mónica; Bertrand, María L; González Plata, Carlos; Andrades-Gómez, José Antonio[et al.] (Taylor & Francis, 2006)
We report the first clinical case of transplantation of autologous bone marrow-derived cells in vitro exposed to a novel recombinant human transforming growth factor (rhTGF)-β1 fusion protein bearing a collagen-binding ... -
Characterization of adult stem/progenitor cell populations from bone marrow in a three-dimensional collagen gel culture system.
Claros-Gil, Silvia; Rodríguez-Losada, Noela; Cruz, Encarnación; Guerado-Parra, Enrique; Becerra-Ratia, José; Andrades-Gómez, José Antonio[et al.] (Sage Publications, 2012-09-01)
Stem cell transplantation therapy using mesenchymal stem cells (MSCs) is considered a useful strategy. Although MSCs are commonly isolated by exploiting their plastic adherence, several studies have suggested that there ... -
Dendrimer surface orientation of the RGD peptide affects mesenchymal stem cell adhesion.
Vida-Pol, Yolanda; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Claros-Gil, Silvia; Becerra-Ratia, José; Andrades-Gómez, José Antonio; Pérez-Inestrosa, Ezequiel[et al.] (Royal Society of Chemistry, 2016-05-17)
Mesenchymal stem cells (MSCs) are promising candidates for a range of tissue regeneration applications. Adequate scaffolds are necessary for their application in vivo, where interactions between cells and the surface ... -
Galanin and Neuropeptide Y Interaction Enhances Proliferation of Granule Precursor Cells and Expression of Neuroprotective Factors in the Rat Hippocampus with Consequent Augmented Spatial Memory
Mirchandani-Duque, Marina; Barbancho-Fernández, Miguel Ángel; López-Salas, Alexander; Álvarez-Contino, José Erik; García-Casares, Natalia; Fuxe, Kjell; Borroto Escuela, Dasiel Óscar; Narváez-Peláez, Manuel[et al.] (IOAP-MPDI, 2022-06-01)
Dysregulation of hippocampal neurogenesis is linked to several neurodegenereative diseases, where boosting hippocampal neurogenesis in these patients emerges as a potential therapeutic approach. Accumulating evidence for ... -
In Vivo Bioluminescence Imaging of Cell Differentiation in Biomaterials: A Platform for Scaffold Development.
Bagó, Juli R; Aguilar, Elisabeth; Alieva, María; Soler-Botija, Carolina; Vila, Olaia F; Claros-Gil, Silvia; Andrades-Gómez, José Antonio; Becerra-Ratia, José; Rubio, Nuria; Blanco, Jerónimo[et al.] (Mary Ann Liebert, 2012-12-19)
In vivo testing is a mandatory last step in scaffold development. Agile longitudinal noninvasive real-time monitoring of stem cell behavior in biomaterials implanted in live animals should facilitate the development of ... -
Induction of superficial zone protein (SZP)/ lubricin/PRG 4 in muscle-derived mesenchymal stem/progenitor cells by transforming growth factor-b1 and bone morphogenetic protein-7
Andrades-Gómez, José Antonio; Motaung, Shirley C; Jiménez-Palomo, Pedro; Claros-Gil, Silvia; López-Puerta, José M.; Becerra-Ratia, José; Schmid, Thomas M.; Reddi, A. Hari[et al.] (Springer Nature, 2012-04-10)
Introduction Articular cartilage (AC) is an avascular tissue with precise polarity and organization. The three distinct zones are: surface, middle and deep. The production and accumulation of the superficial zone protein ... -
Large-Scale Dendrimer-Based Uneven Nanopatterns for the Study of Local RGD Density Effects on Cell Adhesion
Lagunas, Anna; Castaño, Albert G; Artés, Juan M; Vida-Pol, Yolanda; Collado-Martín, Daniel; Pérez-Inestrosa, Ezequiel; Gorostiza, Pau; Claros-Gil, Silvia; Andrades-Gómez, José Antonio; Samitier, Josep[et al.] (2014)
Cell adhesion processes are governed by the nanoscale arrangement of the extracellular matrix (ECM), being more affected by local rather than global concentrations of cell adhesive ligands. In many cell-based studies, ... -
Regenerative Therapies in Dry Eye Disease: From Growth Factors to Cell Therapy
Villatoro, Antonio J; Fernández, Viviana; Claros-Gil, Silvia; Alcoholado Cueto, Cristina; Cifuentes-Rueda, Manuel; Merayo-Lloves, Jesús; Andrades-Gómez, José Antonio; Becerra-Ratia, José[et al.] (MDPI, 2017)
Dry eye syndrome is a complex and insidious pathology with a high level of prevalence among the human population and with a consequently high impact on quality of life and economic cost. Currently, its treatment is ... -
Safety and efficacy of the mesenchymal stem cell in feline eosinophilic keratitis treatment
Villatoro, Antonio J; Claros-Gil, Silvia; Fernández, Viviana; Alcoholado Cueto, Cristina; Fariñas Guerrero, Fernando; Becerra-Ratia, José; Andrades-Gómez, José Antonio[et al.] (BioMed Central, 2018)
Background: Feline eosinophilic keratitis (FEK) is a chronic keratopathy caused by a suspected immune mediated response to an unknown antigenic stimulus. The purpose of this study was to investigate the safety and therapeutic ... -
Selection and induction of rat skeletal muscle-derived cells to the chondro-osteogenic lineage.
Claros-Gil, Silvia; Alonso, Mónica; Becerra-Ratia, José; Andrades-Gómez, José Antonio (CMB Association, 2008-10-26)
Bone marrow (BM) has been long established as the main source of pluripotential mesenchymal stem cells (MSCs), and has been so far the main recognized source of osteoprogenitor cells that ... -
Semaphorin5A expression in the developing chick telencephalon.
Pineda Tenor, Daniel; Garcia Diaz, Beatriz; Olmos, José Luis; Dávila-Cansino, José Carlos; Real-Avilés, María Ángeles; Guirado-Hidalgo, Salvador[et al.] (Elsevier, 2005)
In the present study, we analyzed the expression of Semaphorin5A (Sema5A), a gene implicated in axon guidance and many other processes of neuronal development, in the developing chick telencephalon. By using a heterologous ... -
Skeletal Regeneration by Mesenchymal Stem Cells: What Else?
Andrades´-Gómez, José Antonio; Claros-Gil, Silvia; Jiménez-Palomo, Pedro; López-Puerta, José María; Zamora-Navas, Plácido; Guerado-Parra, Enrique; Monleón-Pradas, Manuel; Araque, María Carmen; Becerra-Ratia, José[et al.] (InTech, 2011)
When regenerative medicine started several years ago, the main goal was for the implanted cells to directly participate in the reconstruction of the damaged tissue. But now, after the reported paracrine effects in several ... -
The effect of type I collagen on osteochondrogenic differentiation in adipose-derived stromal cells in vivo.
Alonso, Mónica; Claros-Gil, Silvia; Becerra-Ratia, José; Andrades-Gómez, José Antonio (Elsevier, 2008)
Background The objective of this study was to investigate whether type I collagen would elicit in vivo bone formation of passaged rat adipose-derived adult stromal cells (ADASC) placed extraskeletally. Methods After ... -
Use of Adipose-Derived Mesenchymal Stem Cells in Keratoconjunctivitis Sicca in a Canine Model
Villatoro, Antonio J.; Fernández, Viviana; Claros-Gil, Silvia; Rico-LLanos, Gustavo Adolfo; Becerra-Ratia, José; Andrades-Gómez, José Antonio[et al.] (Wiley, 2015)
Keratoconjunctivitis sicca (KCS) or dry eye disease (DED) is an immune-mediated multifactorial disease, with high level of prevalence in humans and dogs. Our aim in this study was to investigate the therapeutic effects of ...