Listar FP - Artículos por tipo "info:eu-repo/semantics/article"
Mostrando ítems 1-20 de 106
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A revised electronic version of RUCAM for the diagnosis of DILI
(Wiley, 2022)Background and Aims: Roussel Uclaf Causality Assessment Method (RUCAM) for DILI has been hindered by subjectivity and poor reliability. We sought to improve the RUCAM using data from the Drug-Induced Liver Injury Network ... -
An extended reconstruction of human gut microbiota metabolism of dietary compounds.
(Springer Nature, 2021-08-05)Understanding how diet and gut microbiota interact in the context of human health is a key question in personalized nutrition. Genome-scale metabolic networks and constraint-based modeling approaches are promising to ... -
Análisis de la determinación de niveles de tiopurínicos en pacientes pediátricos con enfermedad inflamatoria intestinal
(Elsevier, 2020-06-24)Introducción y objetivos Las tiopurinas son fármacos muy empleados para el mantenimiento de la remisión en pacientes con enfermedad inflamatoria intestinal. Se conocen cuáles son los niveles plasmáticos óptimos, y existe ... -
Analysis of Healthcare Professionals’ and Institutions’ Roles in Twitter Colostomy Information
(IOAP-MDPI, 2023-01-11)Social media represents a powerful tool for disseminating verified health information on topics such as colostomy, and the roles of healthcare professionals and institutions to ensure the veracity of the information conveyed ... -
Anticonvulsant-induced Toxic Epidermal Necrolysis: Monitoring the Immunologic Response.
(Elsevier BV, 2000)Background Toxic epidermal necrolysis is a severe reaction with skin involvement induced by different drugs and other agents. The mechanisms implicated in the induction of the reaction are poorly understood. Objective To ... -
Approach to patients with diabetes and obesity in primary care
(Elsevier, 2023-10-17)Aims: The aim of this study is to analyse the effect of pharmacological and non-pharmacological treatment on weight control in patients with diabetes and obesity. Design: Epidemiological, descr ... -
Bioactivity of food melanoidins is mediated by gut microbiota.
(Elsevier, 2020)Melanoidins are an important component of the human diet (average consumption 10g/day), which escape gastrointestinal digestion and are fermented by the gut microbiota. In this paper melanoidins from different food sources ... -
Biomarkers of idiosyncratic drug-induced liver injury (DILI) - a systematic review
(Taylor & Francis, 2021-11-15)Introduction: Idiosyncratic drug-induced liver injury (DILI) is an unpredictable event, and there are no specific biomarkers that can distinguish DILI from alternative explanations or predict its clinical outcomes. Areas ... -
Capturing the value of vaccination within health technology assessment and health economics: Literature review and novel conceptual framework
(Elsevier, 2022-05)The objective of this analysis was to focus on health technology assessment systems to identify relevant value concepts in order to improve current EE of non-pandemic vaccines. Methods: Following a literature review, a ... -
Causes of death in patients with locally advanced head and neck cancer treated with radiotherapy and systemic therapy
(BMC Springer Nature, 2019)Background: To investigate the incidence of non-cancer mortalities and prognostic factors associated with competitive causes of death in a homogeneous cohort of patients with locally advanced head and neck cancer treated ... -
Central Venous Sinus Thrombosis in a Boy With Acute Severe Ulcerative Colitis.
(Frontiers, 2019-02-01)Cerebral venous sinus thrombosis (CVST) in childhood is uncommon. Certain diseases predispose patients to CVST, such as inflammatory bowel disease (IBD), which is considered a risk factor for developing thrombosis, which ... -
Characterization of drug-induced liver injury associated with drug reaction with eosinophilia and systemic symptoms in two prospective DILI registries
(Springer Nature, 2023-12-05)Idiosyncratic drug-induced liver injury (DILI) associated with drug reactions with eosinophilia and systemic symptoms (DRESS) is poorly characterized among patients of Western countries. We aimed to comprehensively assess ... -
Characterizing Highly Cited Papers in Mass Cytometry through H-Classics
(IOAP-MPDI, 2021-02-02)Mass cytometry (CyTOF) is a relatively novel technique for the multiparametric analysis of single-cell features with an increasing central role in cell biology, immunology, pharmacology, and biomedicine. This technique ... -
Clinical characteristics and outcome of drug-induced liver injury in the older patients: from the young-old to the oldest-old
(Wiley, 2020-11-11)Old patients with hepatotoxicity have been scarcely studied in idiosyncratic drug-induced liver injury (DILI) cohorts. We sought for the distinctive characteristics of DILI in older patients across age groups. A total of ... -
Clinical presentation, causative drugs and outcome of patients with autoimmune features in two prospective DILI registries
(Wiley, 2023)Background & aims: Idiosyncratic drug-induced liver injury (DILI) with autoimmune features is a liver condition with laboratory and histological characteristics similar to those of idiopathic autoimmune hepatitis (AIH), ... -
Comprehensive analysis and insights gained from long-term experience of the Spanish DILI Registry
(Elsevier, 2021-02-01)Background & aims: Prospective drug-induced liver injury (DILI) registries are important sources of information on idiosyncratic DILI. We aimed to present a comprehensive analysis of 843 patients with DILI enrolled into ... -
Control compounds for preclinical drug-induced liver injury assessment: Consensus-driven systematic review by the ProEuroDILI network
(Elsevier, 2024)Background & Aims Idiosyncratic drug-induced liver injury (DILI) is a complex and unpredictable event caused by drugs, and herbal or dietary supplements. Early identification of human hepatotoxicity at preclinical stages ... -
Controlled administration of penicillin to patients with a positive history but negative skin and specific serum IgE tests.
(Wiley, 2002)Although subjects with a positive history of immediate allergy to penicillin and negative skin test are considered to tolerate penicillin, they may develop an immediate reaction despite negative skin and serum specific IgE ... -
Cost-effectiveness of omalizumab in severe persistent asthma in Spain: a real-life perspective.
(Taylor & Francis, 2014-11-24)Objectives: To determine the cost-effectiveness of omalizumab compared with routine clinical practice in the treatment and control of severe persistent asthma. Methods: Cost-effectiveness analysis using pre- and ... -
Critical Review of Gaps in the Diagnosis and Management of Drug-Induced Liver Injury Associated with Severe Cutaneous Adverse Reactions
(MDPI, 2021-11-15)Drug-induced liver injury (DILI) encompasses the unexpected damage that drugs can cause to the liver. DILI may develop in the context of an immunoallergic syndrome with cutaneous manifes- tations, which are sometimes severe ...