Listar FP - Artículos por título
Mostrando ítems 50-69 de 122
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Factors associated with health-related quality of life in community-dwelling older adults: a multinomial logistic analysis.
(MDPI, 2019-11-01)The main aim of this study was to determine the association of various clinical, functional and pharmacological factors with the physical (PCS) and mental (MCS) summary components of the health-related quality of life ... -
Genetic polymorphisms of CYP2C9 and CYP2C19 are not related to drug-induced idiosyncratic liver injury (DILI)
(2007-01-29)Background and purpose: The general view on the pathogenesis of drug-induced idiosyncratic liver injury (DILI) is that parent compounds are rendered hepatotoxic by metabolism, mainly by cytochrome (CYP) 450, although other ... -
Genome-wide association study of multiple sclerosis confirms a novel locus at 5p13.1
(Public Library of Science, 2012)Multiple Sclerosis (MS) is the most common progressive and disabling neurological condition affecting young adults in the world today. From a genetic point of view, MS is a complex disorder resulting from the combination ... -
Hepatic safety of atypical antipsychotics: current evidence and future directions
(Springer, ADIS INT LTD, 2016-10)The newer atypical antipsychotic agents (AAPs) represent an attractive therapeutic option for a wide range of psychotic disorders, including schizophrenia and bipolar mania, because of the reduced risk of disabling ... -
Herbal and dietary supplement-induced liver injuries in the spanish DILI registry
(Elsevier, 2018-01)There have been increasing reports of liver injury associated with use of herbal and dietary supplements.We collected and analyzed data on demographic and clinical features, along with biochemical parameters, of 32 patients ... -
Herbal and dietary supplements-induced liver injury in Latin America: Experience from the LATINDILI Network
(Elsevier, 2022)Background: Herbal and dietary supplements (HDS) consumption, a growing cause of hepatotoxicity, is a common practice among Latin-American populations. Objectives: To evaluate clinical, laboratory features and outcome ... -
Herbst’s Triad as a Manifestation of Gastroesophageal Reflux Disease
(Wiley, 2021)The Herbst triad (HT) was described in 1976 by Herbst et al. (1) when detecting the association of iron deficiency anemia, hypoalbuminemia and clubbing in 3 children with hiatal hernia and severe esophagitis secondary to ... -
Histological and serological features of acute liver injury after SARS-CoV-2 vaccination
(Elsevier, 2022)Liver injury with autoimmune features after vaccination against Severe Acute Respiratory Syndrome Coronavirus type 2 (SARS-CoV-2) is increasingly reported. We investigated a large international cohort of patients with acute ... -
Historical exposure to persistent organic pollutants and cardiovascular disease: A 15-year longitudinal analysis focused on pharmaceutical consumption in primary care
(Elsevier, 2021-07-02)Objectives: To explore the potential contribution of historical POP exposure to 15-year pharmaceutical consumption in relation to CVD. Methods: This study is framed within GraMo adult cohort. Participants (n = 387) were ... -
HLA class II alleles in patients with multiple sclerosis in the Biscay province (Basque Country, Spain)
(Springer, 2009)Genetic susceptibility to multiple sclerosis (MS) is associated with genes of the major histocompatibility complex, particularly with the HLA DRB1*1501-DQA1*0102-DQB1*0602 haplotype in Caucasians. To investigate the ... -
IFNAR1 and IFNAR2 polymorphisms confer susceptibility to multiple sclerosis but not to interferon-beta treatment response
(Elsevier, 2005)We investigated the role of three polymorphisms in the IFNAR1 (SNPs 18417 and -408) and IFNAR2 (SNP 11876) genes in multiple sclerosis (MS) susceptibility and in the IFNbeta treatment response in a group of 147 patients ... -
IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D).
(Public Library of Science, 2009)Background:IL-2 receptor (IL2R) alpha is the specific component of the high affinity IL2R system involved in the immune response and in the control of autoimmunity. Methods and Results: Here we perform a replication and ... -
Impact of pediatric inflammatory bowel disease on caregivers' work productivity: A multicenter study by the SEGHNP
(Wiley, 2024)Objectives/Background: Pediatric inflammatory bowel disease (PIBD) poses significant challenges not only to patients but also to their families, particularly affecting the work productivity of caregivers. This Spanish ... -
Impact of the COVID-19 pandemic on the digitization of routine pediatric practice in Spain: A nationwide survey study.
(Frontiers, 2023-02-14)Introduction: The COVID-19 pandemic forced a change in the working dynamics of all healthcare professionals, leading to the sudden introduction of telemedicine. Although until that moment telemedicine applications had been ... -
In vitro batch fermentation protocol to study the contribution of food to gut microbiota composition and functionality
(Springer Nature, 2021)Knowledge about the effect of foods on gut microbiota composition and functionality is expanding. To isolate the effect of single foods and/or single nutrients (i.e. fibre, polyphenols), this protocol describes an in vitro ... -
In vitro T-cell responses to beta-lactam drugs in immediate and nonimmediate allergic reactions.
(Wiley, 2001)Background: Beta-Lactam drugs may induce both cellular and humoral allergic reactions, and there is evidence that T cells play an important role in the pathogenesis of these reactions. The aim of this work was to assess ... -
Incidence and prevalence of acute hepatitis E virus infection in patients with suspected Drug-Induced Liver Injury in the Spanish DILI Registry
(2020)Background and Aims: Drug-induced liver injury (DILI) presents with a wide phenotypic spectrum requiring an extensive differential diagnosis. Hepatitis E virus (HEV) is not systematically ruled out during acute hepatitis ... -
Influence of the technique and comorbidities in hypofractionated radiotherapy for prostate cancer
(Springer Link, 2020)To analyze the differences in toxicity and biochemical relapse-free survival with hypofractionated radiotherapy with three-dimensional radiotherapy (3D-CRT) or volumetric arc therapy (VMAT) for prostate cancer taking into ... -
Innova 2020: A Follow-Up Study of the Fecal Microbiota of Infants Using a Novel Infant Formula between 6 Months and 12 Months of Age
(MDPI, 2023)The World Health Organization recommends exclusive breastfeeding until at least six months of age, with breast milk or formula being the primary food source until one year, followed by the gradual introduction of other ... -
Insulin-like Growth Factor II Prevents MPP+ and Glucocorticoid Mitochondrial-Oxidative and Neuronal Damage in Dopaminergic Neurons
(MDPI, 2021-12-24)Stress seems to contribute to Parkinson’s disease (PD) neuropathology, probably by dysregulation of the hypothalamic–pituitary–adrenal axis. Key factors in this pathophysiology are oxidative stress and mitochondrial ...