Listar COG - Artículos por fecha de publicación
Mostrando ítems 1-20 de 61
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Expression of the Antiapoptotic Proteins Clusterin and Bcl-2 in Laryngeal Squamous Cell Carcinomas
(Karger, 2006)Bcl-2 and clusterin genes have been related to the inhibition of apoptosis, an event that plays a key role in malignant transformation and in invasive disease. In this work, we determine the significance of clusterin and ... -
Anticlusterin treatment of breast cancer cells increases the sensitivities of chemotherapy and tamoxifen and counteracts the inhibitory action of dexamethasone on chemotherapy-induced cytotoxicity
(BMC Springer Nature, 2007-12-13)Introduction: Overexpression of the apoptosis-related protein clusterin is associated with breast cancer development and tumor progression. We describe the use of clusterin-specific antisense oligonucleotides and antibodies ... -
Genetic Polymorphisms in Folate Pathway Enzymes, DRD4 and GSTM1 Are Related to Temporomandibular Disorder.
(BMC, 2011-05-26)Methods A case-control study was designed to evaluate the impact of genetic polymorphisms above described on TMD. A total of 229 individuals (69% women) were included at the study; 86 were patients with TMD and 143 were ... -
Quantitative real-time polymerase chain reaction improves conventional microbiological diagnosis in an outbreak of brucellosis due to ingestion of unpasteurized goat cheese.
(Elsevier, 2011-11)Rapid diagnosis of individuals involved in brucellosis outbreaks can sometimes be difficult with conventional microbiological techniques. We analyzed, for the first time, the diagnostic yield of a real-time polymerase chain ... -
Detection methods predict differences in biology and survival in breast cancer patients
(BMC Springer Nature, 2012)Background: The aim of this study was to measure the biological characteristics involved in tumorigenesis and the progression of breast cancer in symptomatic and screen-detected carcinomas to identify possible difference ... -
Cambios emocionales y alteraciones en la Inmunoglobulina A (IgA) tras el tratamiento psicológico en mujeres víctimas de violencia doméstica
(Universidad de Murcia, 2012)El objetivo de este estudio ha sido determinar, en mujeres víctimas de maltrato, los beneficios de un tratamiento psicológico y evaluar su impacto en la salud psicológica y en el sistema inmune. Las participantes fueron ... -
Resolution of diabetes mellitus and metabolic syndrome in normal weight 24-29 BMI patients with one anastomosis gastric bypass.
(Ediciones Arán, 2012)Thirteen diabetic patients operated by One Anastomosis Gastric Bypass (BAGUA), were evaluated in the preoperative period and 1,3 and 6 months after surgery. Body weight and composition, Fasting Plasma Glucose, HbA1c levels, ... -
Low Sex Ratio in Children of Professional Basketball Players in Spain
(Wiley, 2012-05)The aim of this study was to ascertain the variations in the reproductive sex ratio (number of men to number of women) among male professional basketball players in Spain. This retrospective, cross-sectional study is based ... -
Genetic polymorphisms of serotonin transporter and receptor 1A could influence success during embryo implantation and maintaining of pregnancy.
(Elsevier SCI LTD, 2013-02-13)Objective: To explore whether serotonin-related gene polymorphisms influence clinical outcomes of in vitro fertilization (IVF) treatment in recipients using donated oocytes. Design: Nested case-control study. Setting: ... -
Comparative Clinical Study of Different Multiplex Real Time PCR Strategies for the Simultaneous Differential Diagnosis between Extrapulmonary Tuberculosis and Focal Complications of Brucellosis.
(PLOS, 2013-12-12)Background Both brucellosis and tuberculosis are chronic-debilitating systemic granulomatous diseases with a high incidence in many countries in Africa, Central and South America, the Middle East and the Indian subcontinent. ... -
Changes of Body Composition in Patients with BMI 23–50 After Tailored One Anastomosis Gastric Bypass (BAGUA): Influence of Diabetes and Metabolic Syndrome
(Springer Nature, 2014)We studied 79 (37 diabetic and 42 non-diabetic) patients (BMI 23–50) who completed all evaluation appointment (preoperative, 10 days, 1, 3, 6, and 12 months) after tailored BAGUA for obesity, diabetes, or diabesity. Patients ... -
Differential behavior of serum and red blood cell folate during a treatment with levofolinic acid. Gender differences.
(Clinical Laboratory Publications, 2014-01-01)Background: Folates are essential nutrients that maintain nucleotide synthesis and methylation reactions. Folate levels depend essentially on the diet. In the present work, the changes in the folate-homocysteine (Hcy) ... -
Downregulation of clusterin mediates sensitivity to protein kinase inhibitors in breast cancer cells.
(Lipincott, 2015)The efficacy of protein kinase inhibitors (PKIs) has been shown in clinical assays for cancer, but as isolated agents, they only have a modest effect. One of the most important characteristics of mitogen-activated PKIs is ... -
Validation and comparison of instruments to identify frail patientes in primary care settings: Study protocol
(BMC Springer Nature, 2016)Background: In the last few years several indices and tools, aimed at identifying frail subjects in various care settings have been developed. However, to date none of them has been incorporated into usual practice in the ... -
Factors that influence treatment delay in patients with colorectal cancer
(IMPACT JOURNALS LLC, 2017)A prospective study was performed of patients diagnosed with colorectal cancer (CRC), distinguishing between colonic and rectal location, to determine the factors that may provoke a delay in the first treatment (DFT) ... -
Timeline of Intestinal Adaptation After Malabsortive Surgery: Effect of Luminal Nutrients, Biliopancreatic Secretion, and Glutamine Supplementation
(Springer, 2017)Three types of surgery were performed using a porcine model: biliopancreatic bypass (BPBP), massive (75%) short bowel resection as the positive control, and a sham operation (transection) as the negative control. We measured ... -
Development of trauma systems in Europe-reports from England, Germany, the Netherlands, and Spain
(Orthopaedic Trauma Association, 2019)Major trauma systems have evolved in many European countries and have resulted in improved care in terms of mortality and morbidity. Many of the systems have similar history, with reports of either poor services, or a ... -
Toll-Like Receptor 2 Promoter -196 to -174 Deletion Affects CD4 Levels Along Human Immunodeficiency Virus Infection Progression.
(Oxford Academy, 2020)Toll-like receptor 2 (TLR2) plays a key role in innate immune response recognizing molecular patterns expressed by pathogens. rs111200466 is a TLR2 promoter insertion/deletion polymorphism with contradictory data about its ... -
Is the bone tissue of the femoral neck demineralisedin patients with hip fracture?
(Elsevier, 2020-02-15)The aim of this study is to establish the falsifiability of the "osteoporotic hypothesis" for hip fracture, according to which the bone density and mineral composition of bone tissue in patients with hip fracture is poorer ... -
Age related changes in the bone microstructure in patients with femoral neck fractures.
(Elsevier, 2020-02-16)Background The objective of this study was to analyze the correlation between various bone structural features and age. Study Design & Methods A total of 29 consecutive patients who suffered an intracapsular hip fracture ...