Listar BMB - Artículos por título
Mostrando ítems 127-146 de 168
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ReadqPCR and NormqPCR: R packages for the reading, quality checking and normalisation of RT-qPCR quantification cycle (Cq) data
(BMC, 2012-07)Background: Measuring gene transcription using real-time reverse transcription polymerase chain reaction (RT-qPCR) technology is a mainstay of molecular biology. Technologies now exist to measure the abundance of many ... -
Regulatory role of microRNA in mesenteric lymph nodes after Salmonella Typhimurium infection
Claros-Díaz, Manuel Gonzalo
; Herrera‐Uribe, Juber; Zaldívar‐López, Sara; Aguilar, Carmen; Luque, Cristina; Bautista-Moreno, Rocío; Carvajal, Ana; Garrido, Juan José[et al.] (Veterinary Research, 2018)
Salmonellosis is a gastrointestinal disease caused by non‐typhoidal Salmonella serovars such as Salmonella Typhimu‐ rium. This pathology is a zoonosis, and food animals with subclinical infection constitute a vast reservoir ... -
Regulatory variants: from detection to predicting impact.
(Oxford Academic, 2018-06-08)Variants within non-coding genomic regions can greatly affect disease. In recent years, increasing focus has been given to these variants, and how they can alter regulatory elements, such as enhancers, transcription factor ... -
Role and therapeutic potential of dietary ketone bodies in lymph vessel growth.
(Nature, 2019-07-19)Los vasos linfáticos (LV), revestidos por células endoteliales linfáticas (LEC), son indispensables para la vida1. Sin embargo, el papel del metabolismo en las LEC no se ha dilucidado por completo. En el presente estudio, ... -
Screening of Synergistic Interactions of Epigallocatechin-3-gallate with Antiangiogenic and Antitumor Compounds
Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel; García-Vilas García, Javier Alejandro (Elsevier, 2016-07)
Purpose: To screen for possible synergistic interactions of epigallocatechin-3-gallate (EGCG) with a selection of 10 anti-angiogenic or anti-tumor compounds on the survival of endothelial and tumor cells. Methods: Human ... -
Secretory Profile of Adipose-Tissue-Derived Mesenchymal Stem Cells from Cats with Calicivirus-Positive Severe Chronic Gingivostomatitis
Villatoro, Antonio J.; Martín Astorga, María del Carmen; Alcoholado Cueto, Cristina; Kazantseva, Liliya; Cárdenas García, Casimiro; Fariñas Guerrero, Fernando; Becerra-Ratia, José; Visser, Rick[et al.] (IOAP-MPDI, 2022-05-25)
The feline calicivirus (FCV) causes infections in cats all over the world and seems to be related to a broad variety of clinical presentations, such as feline chronic gingivostomatitis (FCGS), a severe oral pathology in ... -
Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis.
(Cell Press, 2020-04-07)El metabolismo de las células endoteliales (CE) es un objetivo emergente para la terapia antiangiogénica en la angiogénesis tumoral y la neovascularización coroidea (CNV), pero se sabe poco sobre los transcriptomas metabólicos ... -
Spatial dynamics of synthetic microbial mutualists and their parasites.
(PLOS, 2017-08-21)A major force contributing to the emergence of novelty in nature is the presence of cooperative interactions, where two or more components of a system act in synergy, sometimes leading to higher-order, emergent phenomena. ... -
Spatial self-organization in hybrid models of multicellular adhesion.
(American Institute of Physics, 2016-10-26)Spatial self-organization emerges in distributed systems exhibiting local interactions when nonlinearities and the appropriate propagation of signals are at work. These kinds of phenomena can be modeled with different ... -
Structural Bases for the Allergenicity of Fra a 1.02 in Strawberry Fruits.
Orozco-Navarrete, Begoña; Kaczmarska, Zuzanna; Dupeux, Florine; Garrido-Arandia, María; Pott, Delphine; Díaz-Perales, Araceli; Casañal, Ana; Márquez, José A.; Valpuesta-Fernández, Victoriano; Merchante-Berg, Catharina[et al.] (American Chemical Society, 2019-11-27)
Although strawberries are highly appreciated fruits, their intake can induce allergic reactions in atopic patients. These reactions can be due to the patient’s previous sensitization to the major birch pollen allergen Bet ... -
Sustainability in the management of scientific information
Medina-Torres, Miguel Ángel (Springer Nature, 2020-09-25)
The sustainability in the management of scientific information is becoming compromised in this new age of Big Data. Herein, I present and discuss some of the main challenges of this situation in both scientific practice ... -
Synaptotagmins at the endoplasmic reticulum-plasma membrane contact sites maintain diacylglycerol homeostasis during abiotic stress
Ruiz-López, Noemí; Pérez-Sancho, Jessica; Esteban del Valle, Alicia; Haslam, Richard P.; Vanneste, Steffen; Catalá, Rafael; Perea-Resa, Carlos; Van Damme, Daniël; García-Hernández, Selene; Albert, Armando; Vallarino, José; Lin, Jinxing; Friml, Jiří; Macho, Alberto P; Salinas, Julio; Rosado, Abel; Napier, Johnathan A.; Amorim-Silva, Vitor; Botella-Mesa, Miguel Ángel[et al.] (Oxford University Press in behalf of American Society of Plant Biologists, 2021-05-04)
Endoplasmic reticulum–plasma membrane contact sites (ER–PM CS) play fundamental roles in all eukaryotic cells. Arabidopsis thaliana mutants lacking the ER–PM protein tether synaptotagmin1 (SYT1) exhibit decreased PM integrity ... -
Synthesis, characterization and biological evaluation of octyltrimethylammonium tetrathiotungstate
Vega-Granados, Karla; Cruz-Reyes, Juan; Horta-Marrón, José F.; Mari-Beffa, Manuel; Díaz-Rubio, Laura; Córdova-Guerrero, Iván; Chávez-Velasco, Daniel; Ocaña Farfán, María del Carmen; Medina-Torres, Miguel Ángel; Romero-Sánchez, Lilian B.[et al.] (Springer Nature, 2021)
Octyltrimethylammonium tetrathiotungstate salt (ATT-C8) was synthesized and its ability to chelate copper was evaluated. The biological and toxic aspects were evaluated by in vitro and in vivo assays, using bovine aorta ... -
Synthetic circuit designs for earth terraformation
(Springer Nature, 2015-07-18)Background: Mounting evidence indicates that our planet might experience runaway effects associated to rising temperatures and ecosystem overexploitation, leading to catastrophic shifts on short time scales. Remediation ... -
Synthetic collective intelligence.
(Elsevier, 2016)Intelligent systems have emerged in our biosphere in different contexts and achieving different levels of complexity. The requirement of communication in a social context has been in all cases a determinant. The human ... -
Targeting VEGFR-3/-2 signaling pathways with AD0157: a potential strategy against tumor-associated lymphangiogenesis and lymphatic metastases
(BMC, 2017-06-19)La metástasis linfática es una de las principales causas de muerte en pacientes con diferentes tipos de cáncer y es el principal factor pronóstico para la supervivencia de la enfermedad. La formación de nuevos vasos ... -
The Arabidopsis TETRATRICOPEPTIDE THIOREDOXIN-LIKE 1 Gene Is Involved in Anisotropic Root Growth during Osmotic Stress Ad.aptation
Cuadrado-Pedetti, María Belén; Rauschert, Inés; Sainz, María Martha; Amorim-Silva, Vitor; Botella-Mesa, Miguel Ángel; Borsani, Omar; Sotelo-Silveira, Mariana[et al.] (MDPI, 2021-02-07)
Mutations in the Arabidopsis TETRATRICOPEPTIDE THIOREDOXIN-LIKE 1 (TTL1) gene cause reduced tolerance to osmotic stress evidenced by an arrest in root growth and root swelling, which makes it an interesting model to explore ... -
The Marine Fungal Metabolite, AD0157, Inhibits Angiogenesis by Targeting the Akt Signaling Pathway
García-Caballero, Melissa; Cañedo, Librada; Fernández-Medarde, Antonio; Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María (MDPI, 2014-01-16)
En el marco de un programa de selección de inhibidores de la angiogénesis de origen marino, se seleccionó AD0157, un metabolito fúngico de la pirrolidinediona, por sus propiedades angiosupresoras. AD0157 inhibió el crecimiento ... -
The NAC transcription factor FaRIF controls fruit ripening in strawberry
Martín-Pizarro, Carmen; Vallarino Castro, José G.; Osorio-Algar, Sonia; Meco, Victoriano; Urrutia, María; Pillet, Jeremy; Casañal, Ana; Merchante-Berg, Catharina; Amaya Saavedra, Iraida; Willmitzer, Lothar; Fernie, Alisdair R; Giovannoni, James J.; Botella-Mesa, Miguel Ángel; Valpuesta-Fernández, Victoriano; Posé-Padilla, David[et al.] (Oxford University Press, 2021-02-24)
In contrast to climacteric fruits such as tomato, the knowledge on key regulatory genes controlling the ripening of straw- berry, a nonclimacteric fruit, is still limited. NAC transcription factors (TFs) mediate different ... -
The NAC transcription factor FaRIF controls fruit ripening in strawberry.
Martín-Pizarro, Carmen; Vallarino, José G.; Osorio-Algar, Sonia; Meco, Victoriano; Urrutia, María; Pillet, Jeremy; Casañal, Ana; Merchante-Berg, Catharina; Amaya, Iraida; Willmitzer, Lothar; Fernie, Alisdair R.; Giovannoni, James J.; Botella-Mesa, Miguel Ángel; Valpuesta-Fernández, Victoriano; Posé-Padilla, David[et al.] (Oxford University Press [University Publisher], American Society of Plant Biologists [Society Publisher], 2021-02-24)
In contrast to climacteric fruits such as tomato, the knowledge on key regulatory genes controlling the ripening of strawberry, a nonclimacteric fruit, is still limited. NAC transcription factors (TFs) mediate different ...