Listar BMB - Artículos por título
Mostrando ítems 133-152 de 193
-
OliveAtlas: a gene expression atlas tool for olea europaea
(MDPI, 2023-03-10)The olive (Olea europaea L.) is an ancient crop of great importance in the Mediterranean basin due to the production of olive oil and table olives, which are important sources of fat and have benefits for human health. ... -
PainNetworks: A web-based resource for the visualisation of pain related genes in the context of their network associations.
(IASP/Wolters Kluwer, 2013-08-11)We now know of hundreds of genes that have some association with pain. Several genes have been shown to alter pain sensitivity in humans, and can be found in the OMIM database. The Pain Gene Database gives details of genes ... -
Peripheral membrane proteins modulate stress tolerance by safeguarding cellulose synthases
(American Association for the Advancement of Science, 2022-11-16)Controlled primary cell wall remodeling allows plant growth under stressful conditions, but how these changes are conveyed to adjust cellulose synthesis is not understood. Here, we identify the TETRATRICOPEPTIDE THIOREDOXIN-LIKE ... -
PGC-1 alpha activates CYP7A1 and bile acid biosynthesis
(American Society for Biochemistry and Molecular Biology, 2003)Cholesterol 7-alpha-hydroxylase (CYP7A1) is the key enzyme that commits cholesterol to the neutral bile acid biosynthesis pathway and is highly regulated. In the current studies, we have uncovered a role for the transcriptional ... -
Physiological, epigenetic and genetic regulation in some olive cultivars under salt stress.
(Springer Nature, 2019-01-31)Cultivated olive, a typical fruit crop species of the semi-arid regions, could successfully face the new scenarios driven by the climate change through the selection of tolerant varieties to salt and drought stresses. ... -
Pine has two glutamine synthetase paralogs, GS1b.1 and GS1b.2, exhibiting distinct biochemical properties
(Wiley, 2023)The enzyme glutamine synthetase (EC 6.3.1.2) is mainly responsible for the incorporation of inorganic nitrogen into organic molecules in plants. In the present work, a pine (Pinus pinaster) GS1 (PpGS1b.2) gene was identified, ... -
Population dynamics of synthetic terraformation motifs.
(The Royal Society, 2018-07-04)Ecosystems are complex systems, currently experiencing several threats associated with global warming, intensive exploitation and human-driven habitat degradation. Because of a general presence of multiple stable states, ... -
Postharvest changes in LIN5-down-regulated plants suggest a role for sugar deficiency in cuticle metabolism during ripening.
(Elsevier, 2017)The cell wall invertase gene (LIN5) was reported to be a key enzyme influencing sugar uptake of tomato (Solanum lycopersicum) fruit. It was additionally revealed to be a key regulator of total soluble solids content in ... -
A problem-/case-based learning approach as an useful tool for studying glycogen metabolism and its regulation
(2020-09-23)Metabolism and its regulation is one of the most complex and difficult topics for students learning biochemistry. A problem-/case-based learning (PBL) approach can be useful to help biochemistry students to fulfill the ... -
Profiling the Influence of Gene Variants Related to Folate-Mediated One-Carbon Metabolism on the Outcome of In Vitro Fertilization (IVF) with Donor Oocytes in Recipients Receiving Folic Acid Fortification
(IOAP-MPDI, 2022-09-25)Nutritional status and gene polymorphisms of one-carbon metabolism confer a well-known interaction that in pregnant women may affect embryo viability and the health of the newborn. Folate metabolism directly impacts ... -
Proteome-Wide Structural Computations Provide Insights into Empirical Amino Acid Substitution Matrices
(IOAP-MDPI, 2023-01-02)The relative contribution of mutation and selection to the amino acid substitution rates observed in empirical matrices is unclear. Herein, we present a neutral continuous fitness-stability model, inspired by the Arrhenius ... -
Pyroptosis Modulators: New Insights of Gasdermins in Health and Disease.
(MDPI, 2023-08-03)Pyroptosis is an inflammation-dependent type of cell death that has been in the spotlight for the scientific community in the last few years. Crucial players in the process of pyroptosis are the members of the gasdermin ... -
ReadqPCR and NormqPCR: R packages for the reading, quality checking and normalisation of RT-qPCR quantification cycle (Cq) data
(BMC, 2012-07)Background: Measuring gene transcription using real-time reverse transcription polymerase chain reaction (RT-qPCR) technology is a mainstay of molecular biology. Technologies now exist to measure the abundance of many ... -
Regulation of L-ascorbic acid content in Strawberry fruits
(Oxford Academy, 2011-05-11)Plants have several L-ascorbic acid (AsA) biosynthetic pathways, but the contribution of each one to the synthesis of AsA varyies between different species, organs, and developmental stages. Strawberry (Fragaria×ananassa) ... -
Regulatory role of microRNA in mesenteric lymph nodes after Salmonella Typhimurium infection
(Veterinary Research, 2018)Salmonellosis is a gastrointestinal disease caused by non‐typhoidal Salmonella serovars such as Salmonella Typhimu‐ rium. This pathology is a zoonosis, and food animals with subclinical infection constitute a vast reservoir ... -
Regulatory variants: from detection to predicting impact.
(Oxford Academic, 2018-06-08)Variants within non-coding genomic regions can greatly affect disease. In recent years, increasing focus has been given to these variants, and how they can alter regulatory elements, such as enhancers, transcription factor ... -
Role and therapeutic potential of dietary ketone bodies in lymph vessel growth.
(Nature, 2019-07-19)Los vasos linfáticos (LV), revestidos por células endoteliales linfáticas (LEC), son indispensables para la vida1. Sin embargo, el papel del metabolismo en las LEC no se ha dilucidado por completo. En el presente estudio, ... -
Screening of Synergistic Interactions of Epigallocatechin-3-gallate with Antiangiogenic and Antitumor Compounds
(Elsevier, 2016-07)Purpose: To screen for possible synergistic interactions of epigallocatechin-3-gallate (EGCG) with a selection of 10 anti-angiogenic or anti-tumor compounds on the survival of endothelial and tumor cells. Methods: Human ... -
Secretory Profile of Adipose-Tissue-Derived Mesenchymal Stem Cells from Cats with Calicivirus-Positive Severe Chronic Gingivostomatitis
(IOAP-MPDI, 2022-05-25)The feline calicivirus (FCV) causes infections in cats all over the world and seems to be related to a broad variety of clinical presentations, such as feline chronic gingivostomatitis (FCGS), a severe oral pathology in ... -
Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis.
(Cell Press, 2020-04-07)El metabolismo de las células endoteliales (CE) es un objetivo emergente para la terapia antiangiogénica en la angiogénesis tumoral y la neovascularización coroidea (CNV), pero se sabe poco sobre los transcriptomas metabólicos ...