Listar BMB - Artículos por título
Mostrando ítems 33-52 de 168
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Can a minimal replicating construct be identified as the embodiment of cancer?
Solé, Ricard V.; Valverde, Sergi; Rodríguez-Caso, Carlos Francisco
; Sardanyés, Josep (Wiley, 2014-04)
Genomic instability is a hallmark of cancer. Cancer cells that exhibit abnormal chromosomes are characteristic of most advanced tumours, despite the potential threat represented by accumulated genetic damage. Carcinogenesis ... -
Can cell mortality determine division of labor in tissue organization?
Rodríguez-Caso, Carlos Francisco (Elsevier, 2014-06)
Tissue organization comes from the emergence of cell cooperation where cell homeostasis and function are per- formed as a trade-off of two excluding proliferative and differentiated cellular states. By introducing function ... -
Causes of B chromosome variant substitution in the grasshopper Eyprepocnemis plorans
Manrique-Poyato, María Inmaculada; Muñoz-Pajares, Antonio Jesús; Loreto, Vilma; López-León, María Dolores; Cabrero-Hurtado, Josefa; Martínez-Camacho, Juan Pedro[et al.] (Springer, 2006)
We have analysed B chromosome frequency for three consecutive years, B transmission rate at population and individual levels, clutch size, egg fertility and embryoYadult viability in a natural population of the ... -
Characterisation of non-coding genetic variation in histamine receptors using AnNCR-SNP.
Rojano, Elena; García-Ranea, Juan Antonio; Perkins, James Richard (Springer, 2016-06-06)
Almost 90 % of disease-associated genetic variants found using genome wide association studies (GWAS) are located in non-coding regions of the genome. Such variants can affect phenotype by altering important regulatory ... -
Characterization of the activity and the mechanism of action of a new toluquinol derivative with improved potential as an antiangiogenic drug.
Torres-Vargas, José Antonio; Cheng-Sánchez, Iván; Martínez-Póveda, Beatriz Amparo; Medina-Torres, Miguel Ángel; Sarabia-García, Francisco Ramón; García-Caballero, Melissa; Rodríguez-Quesada, Ana María[et al.] (Elsevier, 2022-09-30)
The inhibition of sustained angiogenesis is an attractive approach for the treatment of cancer, blindness and other angiogenesis-dependent diseases. Encouraged by our previous finding that toluquinol, a methyl hydroquinone ... -
Characterizing the involvement of FaMADS9 in the regulation of strawberry fruit receptacle development
Vallarino Castro, José G.; Merchante-Berg, Catharina; Sánchez-Sevilla, José F; De Luis Balaguer, María Angels; Pott, Delphine; Ariza Fernández, María Teresa; Casañal, Ana; Posé-Padilla, David; Vioque, Amalia; Amaya Saavedra, Iraida; Willmitzer, Lothar; Solano, Roberto; Sozzani, Rosangela; Fernie, Alisdair R; Botella-Mesa, Miguel Ángel; Giovannoni, James J.; Valpuesta-Fernández, Victoriano; Osorio-Algar, Sonia[et al.] (Wiley Online Library, 2019-09-18)
FaMADS9 is the strawberry (Fragaria x ananassa) gene that exhibits the highest homology to the tomato (Solanum lycopersicum) RIN gene. Transgenic lines were obtained in which FaMADS9 was silenced. The fruits of these lines ... -
Characterizing the involvement of FaMADS9 in the regulation of strawberry fruit receptacle development
Vallarino, JG; Merchante, C; Sanchez-Sevilla, JF; De Luis Balaguer, MA; Pott, DM; Ariza, MT; Casañal, A; Posé-Padilla, David; Vioque, A; Amaya, I; Willmitzer, L; Solano, R; Sozzani, R; Fernie, AR; Botella, MA; Giovannoni, JJ; Valpuesta, V; Osorio-Algar, Sonia[et al.] (2020)
FaMADS9 is the strawberry (Fragaria x ananassa) gene that exhibits the highest homology to the tomato (Solanum lycopersicum) RIN gene. Transgenic lines were obtained in which FaMADS9 was silenced. The fruits of these lines ... -
Cocaine modulates both glutaminase gene expression and glutaminase activity in the brain of cocaine-sensitized mice
Blanco-Calvo, Eduardo; Campos-Sandoval, José Ángel; Palomino, Ana; Luque-Rojas, María Jesús; Bilbao, Ainhoa; Suárez, Juan; Márquez-Gómez, Javier; Rodriguez-de-Fonseca, Fernando[et al.] (Springer, 2012)
Glutaminase is considered the main Glutamate (Glu) producing enzyme. Two isoforms, liver (LGA) and kidney (KGA) type glutaminases have been identified in neurons. The role of both enzymes in psychopharmacological responses ... -
Coexistence of nestedness and modularity in host–pathogen infection networks.
(Springer Nature, 2020)The long-term coevolution of hosts and pathogens in their environment forms a complex web of multi-scale interactions. Understanding how environmental heterogeneity affects the structure of host–pathogen networks is a ... -
A comparative study of the antiangiogenic activity of hydroxytyrosyl alkyl ethers
Marrero Capitán, Ana Dácil; Castilla, Laura; Espartero Sánchez, José Luis; Madrona, Andrés; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel; Martínez-Póveda, Beatriz Amparo[et al.] (2020-09-22)
The phenolic compound hydroxytyrosol and its derivatives are responsible for some of the health benefits of the intake of virgin olive oil, having shown antiangiogenic properties. In this study, we explored the ... -
Comparison of the anti-angiogenic potential of hydroxytyrosol and five derivatives
López-Jiménez, Auxiliadora; Gallardo, Elena; Espartero Sánchez, José Luis; Madrona, Andrés; Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María[et al.] (Royal Society of Chemistry, 2018)
Hydroxytyrosol is a phenolic compound present in extra virgin olive oil, either in free form or as derivatives, and related to some of the health benefits described for olive oil intake. We have demonstrated previously ... -
Construction of miRNA–mRNA networks for the identification of lung cancer biomarkers in liquid biopsies
Espinosa García, Elena María; Arroyo Varela, Macarena; Larrosa-Jiménez, Rafael; Gómez‑Maldonado, Josefa; Cobo Dols, Manuel Ángel; Claros-Díaz, Manuel Gonzalo; Bautista-Moreno, Rocío[et al.] (Springer Nature, 2022-10-12)
Lung cancer (LC) is the most common cause of cancer death worldwide mostly due to the low survival rate: 75% of cases are identified in advanced stages. In this study, the list of useful biomarkers to make an early diagnosis ... -
Control of tumor angiogenesis and metastasis through modulation of cell redox state
Serrano, José J.; Delgado-Martín, Belén; Medina-Torres, Miguel Ángel (2020-09-22)
Redox reactions pervade all biology. The control of cellular redox state is essential for bioenergetics and for the proper functioning of many biological functions. This review traces a timeline of findings regarding the ... -
Copper-containing mesoporous bioactive glass promotes angiogenesis in an in vivo zebrafish model
Romero-Sánchez, Lilian B.; Mari-Beffa, Manuel; Carrillo Fernández, Paloma; Medina-Torres, Miguel Ángel; Díaz-Cuenca, Aránzazu (2018-10-19)
The osteogenic and angiogenic responses of organisms to the ionic products of degradation of bioactive glasses (BGs) are being intensively investigated. The promotion of angiogenesis by copper (Cu) has been known for more ... -
Crucial Roles of Brassinosteroids in Cell Wall Composition and Structure Across Species: New Insights and Biotechnological Applications
Percio-Vargas, Francisco; Rubio-Valverde, Lourdes; Amorim-Silva, Vitor; Botella-Mesa, Miguel Ángel (Wiley, 2024)
Brassinosteroids (BR) are steroidal phytohormones essential for plant growth, development, and stress resistance. They fulfil this role partially by modulating cell wall structure and composition through the control of ... -
CXCL5 mediates UVB irradiation-induced pain.
(AAAS, 2011-07-06)Many persistent pain states (pain lasting for hours, days, or longer) are poorly treated because of the limitations of existing therapies. Analgesics such as nonsteroidal anti-inflammatory drugs and opioids often provide ... -
Danthron, an Anthraquinone Isolated from a Marine Fungus, Is a New Inhibitor of Angiogenesis Exhibiting Interesting Antitumor and Antioxidant Properties
Vidal-Valenzuela, Isabel; Torres-Vargas, José Antonio; Sánchez López, José María; Trigal Martínez, Mónica; García-Caballero, Melissa; Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María[et al.] (MDPI, 2023-05-15)
The role played by a sustained angiogenesis in cancer and other diseases stimulates the interest in the search for new antiangiogenic drugs. In this manuscript, we provide evidence that 1,8- dihydroxy-9,10-anthraquinone ... -
Dealing with the genetic load in bacterial synthetic biology circuits: convergences with the Ohm's law.
Carbonell-Ballesteros, Max; García-Ramallo, Eva; Montañez, Raúl; Rodríguez-Caso, Carlos Francisco; Macía, Javier (2015)
Synthetic biology seeks to envision living cells as a matter of engineering. However, increasing evidence suggests that the genetic load imposed by the incorporation of synthetic devices in a living organism introduces a ... -
Detection of B chromosomes in interphase hemolymph nuclei from living specimens of the grasshopper Eyprepocnemis plorans
Cabrero-Hurtado, Josefa; Manrique-Poyato, María Inmaculada; Martínez Camacho, Juan Pedro (Karger, 2006)
The two most important evolutionary properties of B chromosomes are their transmission rate (which suggests their selfishness when significantly higher than 0.5) and their net effects on carrier fitness (usually negative ... -
Development and Validation of a Multilingual Lexicon as a Key Tool for the Sensory Analyses and Consumer Tests of Blueberry and Raspberry Fruit
Lippi, Nico; Senger, Elisa; Karhu, Saila; Mezzetti, Bruno; Cianciabella, Marta; Ayvaz Sönmez, Duygu; Fidelis, Marina; Gatti, Edoardo; Höfer, Monika; Ebru Kafkas, Nesibe; Mazzoni, Luca; McCallum, Susan; Olbricht, Klaus; Orsucci, Saverio; Osorio-Algar, Sonia; Pinczinger, Dora; Predieri, Stefano; Rokka, Susanna; Sánchez-Sevilla, José F; Savini, Gianluca; Soria, Carmen; Usadel, Björn; Zucchi, Paolo; Chiara, Medoro[et al.] (IOAP-MDPI, 2023-01-28)
A comprehensive lexicon is a necessary communication tool between the panel leader and panelists to describe each sensory stimulus potentially evoked by a product. In the current scientific breeding and trading scenario, ...