Listar BMB - Artículos por autor "Alonso, Francisco J."
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Glutaminase-2 Expression Induces Metabolic Changes and Regulates Pyruvate Dehydrogenase Activity in Glioblastoma Cells
De los Santos-Jiménez, Juan; Campos-Sandoval, José Ángel; Rosales, Tracy; Ko, Bookyung; Alonso, Francisco J.; Márquez-Gómez, Javier
; DeBerardinis, Ralph J; Mates-Sánchez, José Manuel
[et al.] (MDPI, 2025-01-06)
Glutaminase controls the first step in glutaminolysis, impacting bioenergetics, biosynthesis and oxidative stress. Two isoenzymes exist in humans, GLS and GLS2. GLS is considered prooncogenic and overexpressed in many ...