Listar Biología Molecular y Bioquímica - (BMB) por título
Mostrando ítems 153-172 de 545
-
Danthron, an Anthraquinone Isolated from a Marine Fungus, Is a New Inhibitor of Angiogenesis Exhibiting Interesting Antitumor and Antioxidant Properties
Vidal-Valenzuela, Isabel; Torres-Vargas, José Antonio; Sánchez López, José María; Trigal Martínez, Mónica; García-Caballero, Melissa; Medina-Torres, Miguel Ángel
; Rodríguez-Quesada, Ana María[et al.] (MDPI, 2023-05-15)
The role played by a sustained angiogenesis in cancer and other diseases stimulates the interest in the search for new antiangiogenic drugs. In this manuscript, we provide evidence that 1,8- dihydroxy-9,10-anthraquinone ... -
Dealing with the genetic load in bacterial synthetic biology circuits: convergences with the Ohm's law.
Carbonell-Ballesteros, Max; García-Ramallo, Eva; Montañez, Raúl; Rodríguez-Caso, Carlos Francisco; Macía, Javier (2015)
Synthetic biology seeks to envision living cells as a matter of engineering. However, increasing evidence suggests that the genetic load imposed by the incorporation of synthetic devices in a living organism introduces a ... -
Deciphering breast cancer intertumor heterogeneity: tumor subtyping and analysis of germline genetic variants
(UMA Editorial, 2018-07)INTRODUCCIÓN: El cáncer de mama no es una única enfermedad, sino un conjunto de enfermedades que presentan una gran variabilidad en todos sus componentes: características histopatológicas, respuesta al tratamiento y ... -
Deciphering Strawberry Ripening by Tissue Specific Gene Regulatory Networks
Lucas-Reina, Eva; Trapero-Mozos, Almudena; De Luis Balaguer, María Angels; Martín-Pizarro, Carmen; Ramos-Alvelo, Martín; Sozzani, Rosangela; Botella-Mesa, Miguel Ángel; Valpuesta-Fernández, Victoriano; Posé-Padilla, David[et al.] (2018-07-12)
During ripening, fruits undergo a number of metabolic and physiological changes leading to softening and improvement of characters such as flavor and palatability. Insights into transcriptome changes during strawberry fruit ... -
Deciphering the dynamics of metabolic pathways influencing by controlled atmosphere during post-harvest physiology of cultivated strawberry fruit
Vallarino Castro, José G.; Soria, Carmen; Nikoloski, Zoran; Willmitzer, Lothar; Valpuesta-Fernández, Victoriano; Fernie, Alisdair R; Osorio-Algar, Sonia[et al.] (2014-10-24)
Strawberry (Fragaria × ananassa) fruit is highly appreciated due to its delicate aroma, flavor and nutritional value. However, fruits are highly perishable and deteriorate quickly at ambient temperature. Controlled atmosphere ... -
Deciphering the interaction between plants and the bacterial pathogen Ralstonia solanacearum
(2017-05-08)Deciphering the interaction between plants and the bacterial pathogen Ralstonia solanacearum Alberto P. Macho Shanghai Center for Plant Stress Biology, CAS Center for Excellence in Molecular Plant Sciences; Shanghai ... -
Deciphering the regulatory network of the NAC transcription factor FvRIF, a key regulator of strawberry (Fragaria vesca) fruit ripening
Li, Xiaojinng; Martín-Pizarro, Carmen; Zhou, Leilei; Hou, Bingzhu; Wang, Yuying; Shen, Yuanyue; Li, Bingbing; Posé-Padilla, David; Qin, Guozheng[et al.] (Oxford University Press, 2023-07-28)
The NAC transcription factor ripening inducing factor (RIF) was previously reported to be necessary for the ripening of octoploid strawberry (Fragaria × ananassa) fruit, but the mechanistic basis of RIF-mediated transcriptional ... -
Deciphering the role of plant Synaptotagmins in the tolerance to multiple stresses
(UMA Editorial, 2017-12-01)Las células de todos los organismos están sujetas a estrés, entendiendo éste como condiciones ambientales desfavorables que limitan su normal desarrollo. A diferencia de otros organismos, las plantas no pueden escapar ... -
Deciphering the role of specialized ribosomes in plants´ translation efficiency
(2023)Translation and its regulation play an important role in plant adaptation. Ribosomes have traditionally been considered passive molecular players regarding which RNA to translate. However, this view is changing due to ... -
Del revés: metaloproteinasa de la matriz extracelular 2 y su función en el nucleolo
(2018-09-19)Las metaloproteinasas de la matriz extracelular (MMPs) son proteínas que tradicionalmente han sido ubicadas en el exterior celular y su función ha sido relacionada con la remodelación de la matriz extracelular en procesos ... -
Depth profiling of tomato fruit cuticle during development using Confocal Raman Microscopy
González Moreno, Ana; Domínguez Carmona, Eva María; Mayer, Konrad; Xiao, Nannan; Bock, Peter; Heredia-Bayona, Antonio; Gierlinger, Notburga[et al.] (2022-09-12)
The plant cuticle is defined as the first barrier between the aerial non-lignified organs of land plants and the environment. Some pivotal roles are ascribed to this outermost layer such as acting as support to the plant, ... -
Design and generation of a glutaminase GLS2 conditional knockout mice
Peñalver, Ana; Tosina, Marta; Martín-Rufián, Mercedes; Campos-Sandoval, José Ángel; Alonso-Carrión, Francisco José; Segura-Checa, Juan Antonio; Mates-Sánchez, José Manuel; Ramírez, Miguel Ángel; Gutiérrez-Adán, Alfonso; Márquez-Gómez, Javier[et al.] (2014-10-04)
Mammalian glutaminase (GA; EC 3.5.1.2) is the main enzyme involved in brain generation of glutamate (Glu). This amino acid acts as an excitatory neurotransmitter within the CNS, and it is also implicated in behavioral ... -
Detection and Measurement of Necrosis in Plants.
Minina, Elena A.; Filonova, Lada H; Sánchez-Vera, Victoria; Suárez-Marín, María Fernanda; Daniel, Geoffrey; Bozhkov, Peter V.[et al.] (Humana Press, 2013)
Necrosis plays a fundamental role in plant physiology and pathology. When plants or plant cell cultures are subjected to abiotic stress they initiate rapid cell death with necrotic morphology. Likewise, when plants are ... -
Detection of B chromosomes in interphase hemolymph nuclei from living specimens of the grasshopper Eyprepocnemis plorans
Cabrero-Hurtado, Josefa; Manrique-Poyato, María Inmaculada; Martínez Camacho, Juan Pedro (Karger, 2006)
The two most important evolutionary properties of B chromosomes are their transmission rate (which suggests their selfishness when significantly higher than 0.5) and their net effects on carrier fitness (usually negative ... -
Detection of transposons modifying genome background in probiotics
Aguilera-Cobos, Lorena; Seoane, Pedro; Gonzalo Claros, M.; Moriñigo-Gutiérrez, Miguel Ángel; Balebona-Accino, María del Carmen; Núñez-Serrano, Rafael; Córdoba Caballero, José; Tapia-Paniagua, Silvana Teresa[et al.] (2018-12-10)
The study of probiotic microorganisms is very interesting in the aquaculture field. Administration of live microorganisms in adequate amounts confers some benefits to the host (Kechagia et al. 2013). Even if Shewanella ... -
Determinación de parámetros cinéticos de una nueva glutamina sintetasa en Pinus pinaster
Valderrama-Martín, José Miguel; Ortigosa, Francisco; Ávila-Sáez, Concepción; Cánovas-Ramos, Francisco Miguel; Cañas-Pendón, Rafael Antonio (2018-05-31)
En las plantas, la glutamina sintetasa (GS, EC 6.3.1.2) es una enzima fundamental en el metabolismo del nitrógeno, siendo la responsable de la incorporación del nitrógeno inorgánico en las moléculas, catalizando la ... -
Development and Validation of a Multilingual Lexicon as a Key Tool for the Sensory Analyses and Consumer Tests of Blueberry and Raspberry Fruit
Lippi, Nico; Senger, Elisa; Karhu, Saila; Mezzetti, Bruno; Cianciabella, Marta; Ayvaz Sönmez, Duygu; Fidelis, Marina; Gatti, Edoardo; Höfer, Monika; Ebru Kafkas, Nesibe; Mazzoni, Luca; McCallum, Susan; Olbricht, Klaus; Orsucci, Saverio; Osorio-Algar, Sonia; Pinczinger, Dora; Predieri, Stefano; Rokka, Susanna; Sánchez-Sevilla, José F; Savini, Gianluca; Soria, Carmen; Usadel, Björn; Zucchi, Paolo; Chiara, Medoro[et al.] (IOAP-MDPI, 2023-01-28)
A comprehensive lexicon is a necessary communication tool between the panel leader and panelists to describe each sensory stimulus potentially evoked by a product. In the current scientific breeding and trading scenario, ... -
Development of bioinformatics tools and studies in biomedical association networks for the analysis of human genetic diseases
(UMA Editorial, 2019-11)El presente trabajo de tesis doctoral se centra en el análisis en red y desarrollo de herramientas bioinformáticas para la determinación de las causas que dan lugar a las enfermedades con base genética. Mediante el análisis ... -
Diacylglycerol transport by Arabidopsis Synaptotagmin 1 at ERplasma membrane contact sites under abiotic stress.
Ruiz-López, Noemí; Pérez-Sancho, Jessica; Esteban del Valle, Alicia; García-Hernández, Selene; Huércano Rubens, Carolina; Percio-Vargas, Francisco; Benítez de la Fuente, Francisco; Osorio-Algar, Sonia; Steffen, Vanneste; Lothar, Willmitzer; Napier, Johnathan A.; Perea, Carlos; Salinas, Julio; Amorim-Silva, Vitor; Botella-Mesa, Miguel Ángel[et al.] (2019-11-13)
Bulk lipid transport between membranes within cells involves vesicles, however membrane contact sites have recently been discovered as mediators of non-vesicular lipid transfer. ER-PM contact sites are conserved structures ... -
Dimethylfumarate Inhibits Angiogenesis In Vitro and In Vivo: A Possible Role for Its Antipsoriatic Effect?
García-Caballero, Melissa; Mari-Beffa, Manuel; Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María (Elsevier, 2011-06-02)
Los ésteres de ácido fumárico (FAE) se han utilizado para el tratamiento oral de la psoriasis durante unos 50 años. Dado que una angiogénesis persistente y mantenida está asociada con varias enfermedades cutáneas, incluida ...