Listar Biología Molecular y Bioquímica - (BMB) por título
Mostrando ítems 102-121 de 549
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Calling for reinforcements: the role of TTL proteins in the regulación of cell wall biosynthesis
Percio-Vargas, Francisco; Kesten, Christopher; García-Moreno, Álvaro; Amorim-Silva, Vitor; Castillo-Garriga, Araceli
; Ruiz-López, Noemí; Sánchez-Rodríguez, Clara; Botella-Mesa, Miguel Ángel[et al.] (2022-09-14)
Cellulose is the most abundant organic compound of all biomass on Earth1, with highly relevant roles in plant development and defence. Hence, it is essential to understand the regulation of its biosynthesis to improve the ... -
Can a minimal replicating construct be identified as the embodiment of cancer?
Solé, Ricard V.; Valverde, Sergi; Rodríguez-Caso, Carlos Francisco; Sardanyés, Josep (Wiley, 2014-04)
Genomic instability is a hallmark of cancer. Cancer cells that exhibit abnormal chromosomes are characteristic of most advanced tumours, despite the potential threat represented by accumulated genetic damage. Carcinogenesis ... -
Can cell mortality determine division of labor in tissue organization?
Rodríguez-Caso, Carlos Francisco (Elsevier, 2014-06)
Tissue organization comes from the emergence of cell cooperation where cell homeostasis and function are per- formed as a trade-off of two excluding proliferative and differentiated cellular states. By introducing function ... -
Can several Nobel Prizes be wrong? New insights into Heterotrimeric G proteins signaling
(2019-11-05)Heterotrimeric G proteins (G-proteins), composed of α, β and γ subunits, are essential signaling molecules in most living organism. In humans, G-proteins control vision, smell, taste, and dysfunctions on their signaling ... -
Candidate gene for branched-chain amino acid content in strawberry
Romero, Helena; Pott, Delphine; Segado, Enrique; Vallarino Castro, José G.; Osorio-Algar, Sonia (2022-09-14)
Cultivated strawberry (Fragaria × ananassa) is a berry crop widely appreciated worldwide due to its nutritional and organoleptic properties. However, the main breeding targets in these crops have been the control of flowering ... -
Caracterización anual del metabolismo de las acículas de Pinus pinaster (Aiton) mediante procedimientos transcriptómicos y metabolómicos
Cañas-Pendón, Rafael Antonio; Canales, Javier; Muñoz, C.; Ávila-Sáez, Concepción; García-Martín, María Luisa; Cánovas-Ramos, Francisco Miguel[et al.] (2013-11-04)
El presente trabajo pretende iniciar una serie de estudios sobre el metabolismo nitrogenado en árboles adultos de la conífera Pinus pinaster (Aiton) en condiciones naturales. Durante un año completo se ha caracterizado ... -
Caracterización de la asparraginasa de pino: implicaciones en el desarrollo del sistema vascular
Van Kerckhoven, Sonia Helena; Cañas-Pendón, Rafael Antonio; De-la-Torre-Fazio, Fernando Nicolás; Ávila-Sáez, Concepción; Cánovas-Ramos, Francisco Miguel; Cantón, Francisco R.[et al.] (2014-10-23)
La asparragina es un metabolito clave en plantas para el transporte y reserva temporal de nitrógeno. La principal vía de movilización del nitrógeno contenido en el grupo amido de la asparragina implica a la enzima asparraginasa ... -
Caracterización de la patología amiloide y su relación con la microglía en modelos transgénicos de la enfermedad de Alzheimer
(UMA Editorial, 2020-02-24)En la enfermedad de Alzheimer, la acumulación de beta-amiloide (Abeta) y de fosfo-tau, principales lesiones de esta enfermedad, va acompañada de una respuesta inflamatoria con activación microglial y astroglial. Variantes ... -
Caracterización estructural y funcional de la isoenzima glutaminasa GLS2 y su implicación en cáncer
(UMA Editorial, 2022)Las isoenzimas de glutaminasa (GLS y GLS2) catalizan el primer paso de la ruta de la glutaminolisis (conversión de glutamina a glutamato e iones amonio) y desempeñan un papel clave en crecimiento y proliferación del cáncer. ... -
Caracterización estructural y funcional de la proteína Fra a 1.02 en fruto de fresa
(UMA Editorial, 2020-09-04)La familia de proteínas Fra a 1 de fresa está involucrada en la alergia a las fresas debido a un reconocimiento por parte de las IgE de Betv1. El principal objetivo de esta Tesis fue caracterizar la familia Fra a 1 en ... -
Caracterización funcional de factores de transcripción implicados en morfogénesis y patogenicidad en especies de Verticillium
(UMA Editorial, 2017-07-10)The soildborne pathogen Verticillium dahliae poses a threat to many important crops worldwide. V. dahliae produces highly durable structures, the microsclerotia, which germinate in the presence of root exudates from the ... -
Causes of B chromosome variant substitution in the grasshopper Eyprepocnemis plorans
Manrique-Poyato, María Inmaculada; Muñoz-Pajares, Antonio Jesús; Loreto, Vilma; López-León, María Dolores; Cabrero-Hurtado, Josefa; Martínez-Camacho, Juan Pedro[et al.] (Springer, 2006)
We have analysed B chromosome frequency for three consecutive years, B transmission rate at population and individual levels, clutch size, egg fertility and embryoYadult viability in a natural population of the ... -
Changes in the nuclear proteomic profiling of human glioblastoma cells after glutaminase overexpression
Márquez-Gómez, Javier; Cardona Ramírez, Carolina; Alonso-Carrión, Francisco José; Lobo, Carolina; Campos-Sandoval, José Ángel; Martín Rufián, Mercedes[et al.] (2013)
Human glutaminase (GA) enzymes are the products of two genes, GLS and GLS2. GA isozymes play markedly different roles in tumour biology: GLS isoforms (KGA and GAC) are related to cell growth and proliferation, whereas GLS2 ... -
Characterisation of non-coding genetic variation in histamine receptors using AnNCR-SNP.
Rojano, Elena; García-Ranea, Juan Antonio; Perkins, James Richard (Springer, 2016-06-06)
Almost 90 % of disease-associated genetic variants found using genome wide association studies (GWAS) are located in non-coding regions of the genome. Such variants can affect phenotype by altering important regulatory ... -
Characterization of AtDGK2 in relation to Contact Sites
García-Hernández, Selene; Ruiz-López, Noemí; Botella-Mesa, Miguel Ángel (2019-05-17)
Contact Sites are conserved cellular regions where two membranes of different organelles are very close but not merged. Contact sites between the endoplasmic reticulum (ER) and the plasma membrane (ER-PM CS) play important ... -
Characterization of ripe fruit epidermis-specific transcription factors in strawberry
Sánchez-Gómez, Carlos; Meco, Victoriano; Urrutia, María; Castillo-Garriga, Araceli; Pérez-Sancho, Jessica; Bayer, Emmanuelle M.; Franco-Zorrila, José Manuel; Martín-Pizarro, Carmen; Posé-Padilla, David[et al.] (2021-01-22)
The epidermis is the external cell layer in direct contact with the environment, and it plays essential biological roles. Transcriptome analysis (RNA-seq) of Fragaria vesca fruit receptacles at four ripening stages (green, ... -
Characterization of ripe fruit epidermis-specific transcription factors in strawberry
Sánchez-Gómez, Carlos; Meco, Victoriano; Urrutia, María; Castillo-Garriga, Araceli; Pérez-Sancho, Jessica; Bayer, Emmanuelle M.; Franco-Zorrila, José Manuel; Martín-Pizarro, Carmen[et al.] (2022-09-15)
Transcriptome changes during strawberry fruit ripening have been previously reported using either complete fruits or achenes (actual fruits) and receptacles (fleshy part) separately. In order to perform a more detailed ... -
Characterization of ripe fruit epidermis-specific transcription factors in strawberry
Sánchez-Gómez, Carlos; Meco, Victoriano; Urrutia, María; Castillo-Garriga, Araceli; Pérez-Sancho, Jessica; Bayer, Emmanuelle M.; Franco-Zorrila, José Manuel; Martín-Pizarro, Carmen; Posé-Padilla, David[et al.] (2021-09-13)
The epidermis is the external cell layer in direct contact with the environment, and it plays essential biological roles. Transcriptome analysis (RNA-seq) of Fragaria vesca fruit receptacles at four ripening stages and of ... -
Characterization of ripe fruit epidermis-specific transcription factors in strawberry
Sánchez-Gómez, Carlos; Meco, Victoriano; Urrutia, María; Castillo-Garriga, Araceli; Pérez-Sancho, Jessica; Bayer, Emmanuelle M.; Franco-Zorrila, José Manuel; Martín-Pizarro, Carmen; Posé-Padilla, David[et al.] (2021-07-06)
The epidermis is the external cell layer in direct contact with the environment, and it plays essential biological roles. Transcriptome analysis (RNA-seq) of Fragaria vesca fruit receptacles at four ripening stages (green, ... -
Characterization of ripe fruit epidermis-specific transcription factors in strawberry
Sánchez-Gómez, Carlos; Meco, Victoriano; Urrutia, María; Castillo-Garriga, Araceli; Pérez-Sancho, Jessica; Bayer, Emmanuelle M.; Franco-Zorrila, José Manuel; Martín-Pizarro, Carmen[et al.] (2021-11-26)
The epidermis is the external cell layer in direct contact with the environment, and it plays essential biological roles. Transcriptome analysis (RNA-seq) of Fragaria vesca fruit receptacles at four ripening stages (green, ...