The present work reflects the impact that the manufacturing industries must solve in the application of the ISO 45001: 2018
Standard on Occupational Health and Safety Management Systems. In such, a globalized market where human and material
assets must be preserved for the survival of organizations, management systems based on continuous improvement play an
important role in ensuring compliance with applicable legal requirements, risk management and the opportunities, as well as the
achievement of the best working conditions. The manufacturing industry has not been alien to this evolution; the nature of the
risks present in the different industries, the operations carried out, the machinery, the use of work teams and their processes make
this sector a priority and strategic sector that should be at the forefront of new technologies and rules. The implementation of the
ISO 45001: 2018 standard in the manufacturing industry is a challenge for the implementation of high-level management systems
that guarantee a healthy and safe environment for workers and a strategic and operational decision from the business point of
view based on improving the performance of health and safety at work and increasing competitiveness in an increasingly
demanding market.