Listar por centro "Facultad de Medicina"
Mostrando ítems 1-20 de 1254
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2015 Beers Criteria and STOPP v2 for detecting potencially inappropriate medication in community-dwelling older people: prevalence, profile and risk factors.
Blanco-Reina, Encarnación
; Valdellós, Jenifer; Aguilar-Cano, Lorena; García-Merino, Maria Rosa; Ocaña-Riola, Ricardo; Ariza-Zafra, Gabriel; Bellido-Estevez, Inmaculada[et al.] (Springer, 2019-07-24)
Purpose To comparatively assess the prevalence rates of potentially inappropriate medications (PIMs) obtained by the former and latest versions of American Geriatrics Society Beers Criteria (AGS BC) and screening tool of ... -
A biomechanical study of spherical grip
Martín-Martín, Jaime; Cuesta-Vargas, Antonio (Springer, 2013)
Use of the hand is vital in working life due to the grabbing and pinching it performs. Spherical grip is the most commonly used, due to similarity to the gripping of a computer mouse. Knowledge of its execution and the ... -
A Carboxylesterase 2 Gene Polymorphism as Predictor of Capecitabine on Response and Time to Progression
Ribelles, Nuria; López-Siles, J; Sánchez-Muñoz, Alfonso; Sánchez, E; González, E; Sánchez, MJ; Carabantes, F; Sánchez- Rovira, P; Márquez, A; Dueñas, R; Sevilla, I; Alba-Conejo, Emilio[et al.] (Bentham Science Publishers Ltd, 2008)
Capecitabine is a drug that requires the consecutive action of three enzymes: carboxylesterase 2 (CES 2), cytidine deaminase (CDD), and thymidine phosphorylase (TP) for transformation into 5-fluorouracil (5FU). The ... -
A database and digital signal processing framework for the perceptual analysis of voice quality
Bermúdez-de-Alvear, Rosa María; Corral García, Jesús; Tardón-García, Lorenzo José; Barbancho-Pérez, Ana María; Fernández-Contreras, Elena; Rando-Márquez, Sara; Martínez-Arquero, A. Ginés; Barbancho-Pérez, Isabel[et al.] (2015-09-09)
Introduction. Clinical assessment of dysphonia relies on perceptual as much as instrumental methods of analysis [1]. The perceptual auditory analysis is potentially subject to several internal and external sources of bias ... -
A lower duodenal immune response is associated with an increase of insulin resistance in patients with morbid obesity
Ho-Plágaro, Ailec; Saltiago-Fernández, Concepción; García Serrano, Sara; Rodríguez, Cristina; Garrido-Sánchez, Lourdes; Escamilla-Sánchez, Alejandro; Gonzalo, Montserrat; Montiel Casado, Custodia; Alcaín-Martínez, Guillermo; García-Muñoz, Beatriz; Ruiz-Santana, Natalia; Vázquez Pedreño, Luis; García-Fuentes, Eduardo[et al.] (Springer Nature, 2019-09-25)
The intestinal immune response could play an important role in obesity-related comorbidities. We aim to study the profile of duodenal cytokines and chemokines in patients with morbid obesity (MO), its relation with insulin ... -
A mechanism of RGS14(414)-mediated recovery of an episodic memory loss: implication of GluR2 subunit of AMPA receptor
(Servicio de Publicaciones y Divulgación Científica, 2015)Background and objectives: The ongoing quest for finding treatment against memory loss seen in aging and in many neurological and neurodegenerative diseases, so far has been unsuccessful and more effective and precise ... -
A microRNA signature associated with early recurrence in breast cancer.
Pérez-Rivas, Luis G.; Jerez-Aragonés, José Manuel; Carmona, Rosario; De Luque, Vanessa; Vicioso-Recio, Luis Prudencio; Claros-Díaz, Manuel Gonzalo; Viguera-Mínguez, Enrique; Pajares, Bella; Sánchez-Muñoz, Alfonso; Ribelles, Nuria; Alba-Conejo, Emilio; Lozano-Castro, José[et al.] (PLOS, 2014-03-14)
Recurrent breast cancer occurring after the initial treatment is associated with poor outcome. A bimodal relapse pattern after surgery for primary tumor has been described with peaks of early and late recurrence occurring ... -
A model of increased impulsivity in rats with bilateral parkinsonism treated with Pramipexole
Gago-Calderón, Belén; Jiménez-Urbieta, Haritz; Marín, Concepció; Quiroga-Varela, Ana; Delgado-Alvarado, Manuel; Rodríguez-Oroz, María Cruz[et al.] (2016)
Impulse control disorders (ICD) is a common side effect of the dopaminergic treatment in patients with Parkinson's disease, which is more associated with dopamine agonists than with levodopa. To understand its pathophysiology, ... -
A new framework for advancing in drug-induced liver injury research. The Prospective European DILI Registry.
Bjornsson, Einar S.; Stephens, Camilla; Atallah, Edmond; Robles-Díaz, María Mercedes; Alvarez-Alvarez, Ismael; Gerbes, Alexander L; Weber, Sabine; Stirnimann, Guido; Kullak-Ublick, Gerd A; Cortez-Pinto, Helena; Grove, Jane I.; Lucena-González, María Isabel; Andrade-Bellido, Raúl Jesús; Aithal, Guruprasad P.[et al.] (Wiley, 2023)
Background & Aims: No multi-national prospective study of drug-induced liver injury (DILI) has originated in Europe. The design of a prospective European DILI registry, clinical features and short-term outcomes of the cases ... -
A new pharmacological strategy against treatment-resistant depression
Pineda-Gomez, Juan Pedro; Millón-Peñuela, Carmelo; Cantero García, Noelia; Flores, Marta; Ladrón de Guevara-Miranda, David; Flores-Burgess, Antonio; Díaz-Cabiale, Zaida[et al.] (Elsevier, 2024)
Major depressive disorder affects more than 50 million people in the world. However, 50% of patients don’t respond to two or more drugs or psychotherapeutic treatments, named treatment-resistant depression (TRD). In this ... -
A Partially Protective Vaccine for Fasciola hepatica Induced Degeneration of Adult Flukes Associated to a Severe Granulomatous Reaction in Sheep
Molina-Hernández, Verónica; Ruiz-Campillo, María Teresa; Martínez-Moreno, Francisco Javier; Buffoni, Leandro; Martinez Moreno, Álvaro; Zafra, Rafael; Bautista, María José; Escamilla-Sánchez, Alejandro; Pérez-Caballero, Raúl; Pérez, José[et al.] (MDPI, 2021-09-30)
Fasciolosis is a parasitic disease of livestock causing important economic losses worldwide and it is also a zoonosis. Current therapy relies on the use of anthelmintic drugs, which is no longer sustainable due to the ... -
A phenotypic study of the resistome in a peri-urban ecosystem.
González Román, Ana Carmen; Dib, Amira Leila; González-Doménech, Carmen María; García Valdés, Luz María; López Guarnido, Olga; Espigares Rodríguez, Elena[et al.] (Elsevier, 2023)
Since the discovery of antibiotics, the dispersion of resistance genes has increased exponentially, leading to the current state in which it has become increasingly difficult to achieve an effective treatment for infectious ... -
A randomized open-labeled study to examine the effects of creatine monohydrate and combined training on jump and scoring performance in young basketball players
Vargas-Molina, Salvador; García-Sillero, Manuel; Kreider, Richard B.; Salinas, Enrique; Petro, Jorge Luis; Benítez-Porres, Javier; Bonilla, Diego A.[et al.] (Taylor & Francis Group, 2022-08-08)
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A randomized phase II trial of platinum salts in basal-like breast cancer patients in the neoadjuvant setting. Results from the GEICAM/2006-03, multicenter study
Alba-Conejo, Emilio; Chacón, J. L.; Lluc, A.; Antón, A.; Estévez, L.; Cirauqui, B.; Carrasco, E.; Calvo, L.; Seguí, M.A.; Ribelles, Nuria; Álvarez, R.; Sánchez-Muñoz, Alfonso; Sánchez, R.; Lopez Garcia-Asenjo, J.A.; Rodriguez-Martin, C.; Escudero, M.J.; Albanell, J.[et al.] (Springer, 2012-10)
Abstract Chemotherapy remains as the only systemic treatment option available for basal-like breast cancer (BC) patients. Preclinical models and several phase II studies suggested that platinum salts are active drugs in ... -
A revised electronic version of RUCAM for the diagnosis of DILI
Hayashi, Paul H.; Lucena-González, María Isabel; Fontana, Robert J.; Bjornsson, Einar S.; Aithal, Guruprasad P.; Barnhart, Huiman; González-Jiménez, Andrés; Yang, Qinghong; Gu, Jiezhun; Andrade-Bellido, Raúl Jesús; Hoofnagle, Jay H.[et al.] (Wiley, 2022)
Background and Aims: Roussel Uclaf Causality Assessment Method (RUCAM) for DILI has been hindered by subjectivity and poor reliability. We sought to improve the RUCAM using data from the Drug-Induced Liver Injury Network ... -
A revised electronic version of RUCAM for the diagnosis of DILI.
Hayashi, PH; Lucena-González, María Isabel; Fontana, RJ; Bjornsson, ES; Aithal, GP; Barnhart, H; González-Jiménez, Andrés; Yang, Q; Gu, J; Andrade-Bellido, Raúl Jesús; Hoofnagle, JH[et al.] (LIPPINCOTT WILLIAMS & WILKINS, 2022-07)
Roussel Uclaf Causality Assessment Method (RUCAM) for DILI has been hindered by subjectivity and poor reliability. We sought to improve the RUCAM using data from the Drug-Induced Liver Injury Network (DILIN) and the Spanish ... -
A Role For Galanin N-Terminal Fragment (1-15) In Anxiety And Depression in rats
Millón-Peñuela, Carmelo; Flores-Burgess, Antonio; Narváez-Peláez, Manuel; Borroto Escuela, Dasiel Óscar; Santín-Núñez, Luis Javier; Narváez-Bueno, José Ángel; Fuxe, Kjell; Díaz-Cabiale, Zaida[et al.] (2015-10-06)
Galanin (GAL) is involved in several functions including mood regulation. The GAL N-terminal fragment (1-15) [GAL(1-15)] also participates at central level and a differential role of GAL(1-15) compared with GAL has been ... -
A Role for Galanin N-Terminal Fragment (1–15) in Anxiety- and Depression-Related Behaviors in Rats.
Millón-Peñuela, Carmelo; Flores-Burgess, Antonio; Narváez-Peláez, Manuel; Borroto Escuela, Dasiel Óscar; Santín-Núñez, Luis Javier; Parrado-Romero, Concepción; Narvaez, Jose Angel; Fuxe, Kjell; Díaz-Cabiale, Zaida[et al.] (Oxford Academic, 2015-02-16)
Galanin (GAL) plays a role in mood regulation. In this study we analyzed the action of the active N-terminal fragment [GAL(1–15)] in anxiety- and depression-related behavioral tests in rats. Methods: The effect of ... -
A service-learning educational approach developed the transversal competencies of undergraduate students in an outreach workshop aimed to high school students
In the last decade, research institutes and universities have strengthened the development of outreach activities in the biomedical field, involving researchers and professors as well as graduate students, but with little ... -
A5 region modulation of the cardiorespiratory responses evoked from parabrachial cell bodies in the anaesthetised rat
Dawid-Milner, Marc Stefan; Lara-Muñoz, José Pablo; López de Miguel, M Pilar; López-González, Manuel Víctor; Spyer, KM; González-Barón, Salvador[et al.] (Elsevier, 2003)
We have examined the importance of the A5 region modulating cardiorespiratory responses evoked from the parabrachial complex (PB) in spontaneously breathing rats. Cardiorespiratory changes were analyzed in response to ...