Listar por autor "Borroto-Escuela, Dasiel"
Mostrando ítems 41-47 de 47
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Potentiation of antidepressant effects: NPY1R agonist and ketamine synergy enhances TrkB signaling and neurogenesis in the ventral hippocampus
Arrabal-Gómez, Carlos; Serrano-Castro, Pedro
; Sánchez-Pérez, José Andrés; Garcia-Casares, Natalia; Fuxe, Kjell; Borroto-Escuela, Dasiel; Narváez, Manuel[et al.] (Taylor & Francis, 2024-04-18)
Background: Major Depressive Disorder (MDD) poses a significant challenge to global health, with current treatments often limited by efficacy and onset delays. This study explores the synergistic antidepressant-like effects ... -
Role of the 5-HT1A receptors in the effect of Galanin(1-15) on Fluoxetine-mediated action in the forced swimming test
Flores-Burgess, Antonio; Santín-Núñez, Luis Javier; Díaz-Cabiale, Zaida; Millón-Peñuela, Carmelo; Narváez-Peláez, Manuel; Borroto Escuela, Dasiel Óscar; Narváez-Bueno, José Ángel; Fuxe, Kjell[et al.] (2018-06-28)
Galanin N-terminal fragment (1-15) [GAL(1-15)] modulates the antidepressant effects induced by the 5-HT1A receptor (5-HT1AR) agonist in the forced swimming test (FST) and the binding characteristics and mRNA levels of ... -
Study of g protein-coupled receptor (gpcr) homo- and heteroreceptor complexes interactions in the central nervous system through proximity labelling techniques
(UMA Editorial, 2024)There exists substantial evidence for the existence of GPCR homo and heteroreceptor complexes with allosteric receptor-receptor interactions in the Central Nervous System (CNS). Through the receptor heteromerization the ... -
The 5-HT1A receptors are involved in the effect of galanin(1-15) on fluoxetine-mediated action in the forced swimming test
Millón-Peñuela, Carmelo; Flores-Burgess, Antonio; Gago-Calderón, Belén; Narváez-Peláez, Manuel; Borroto Escuela, Dasiel Óscar; Sturla, Antonella; Jiménez, Vanesa; Narváez-Bueno, José Ángel; Fuxe, Kjell; Santín-Núñez, Luis Javier; Díaz-Cabiale, Zaida[et al.] (2017-07-25)
We have described that Galanin N-terminal fragment (1-15) [GAL(1-15)] is associated with depressive effects and also modulates the antidepressant effects induced by the 5-HT1A receptor (5-HT1AR) agonist 8-OH-DPAT in the ... -
The administration of Galanin N-Terminal fragment (1-15) induces depressant- and anxiogenic effects in rats.
Millón-Peñuela, Carmelo; Flores-Burgess, Antonio; Santín-Núñez, Luis Javier; Parrado-Romero, Concepción; Puigcerver-Martínez, Araceli; Borroto Escuela, Dasiel Óscar; Fuxe, Kjell; Díaz-Cabiale, Zaida; Narváez-Peláez, Manuel; Narváez-Bueno, José Ángel[et al.] (2013-11-21)
Galanin (GAL) is involved in several functions including mood regulation. Converging evidence implicates GAL and GAL receptors in anxiety- and depression-related behaviours. Intracerebroventricular (icv) GAL in animals ... -
Unveiling the Synergistic Interplay of Neuropeptides for Novel Therapeutic Approaches in Neurodegenerative and Depressive Disorders.
Díaz-Sánchez, Estela; López-Salas, Alexander; Álvarez-Contino, José Erik; Barbancho-Fernández, Miguel Ángel; Sánchez-Pérez, José Andrés; Blanco-Reina, Encarnación; Brito Rodríguez, Ismel; Serrano-Castro, Pedro Jesús; Fuxe, Kjell; Borroto Escuela, Dasiel Óscar; García-Casares, Natalia; Narváez-Peláez, Manuel[et al.] (2023)
The intricate relationship between hippocampal neurogenesis dysregulation and neurodegenerative diseases such as Alzheimer's, as well as depression, has sparked an urgent call for innovative therapeutic strategies. Our ...