Listar por autor "Mayorga Mayorga, Cristobalina"
Mostrando ítems 21-39 de 39
-
Genomic variants association with selective hypersensitivityreactions to amoxicillin and clavulanic acid
Nuñez, Rafael; Fernández-Santamaría, Rubén; Salas, María; Bogas, Gador; Diez-Echave, Patricia; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa
; Fernández-Duarte, Tahía Diana[et al.] (Wiley, 2024-06-29)
In summary, there are rare variants found in our patients that could be related to the development of AX or CLV- induced IDHRs. Interestingly, some of these rare variants could be associated with selective response to ... -
IFNAR1 and IFNAR2 polymorphisms confer susceptibility to multiple sclerosis but not to interferon-beta treatment response
Leyva-Fernández, Laura; Fernández Fernández, Óscar; Fedetz, María; Blanco, Eva; Fernández Sánchez, Victoria Eugenia; Oliver-Martos, Begoña; León, Antonio; Pinto-Medel, María-Jesús; Mayorga Mayorga, Cristobalina; Guerrero, Miguel; Luque, Gloria; Alcina, Antonio; Matesanz, Fuencisla[et al.] (Elsevier, 2005)
We investigated the role of three polymorphisms in the IFNAR1 (SNPs 18417 and -408) and IFNAR2 (SNP 11876) genes in multiple sclerosis (MS) susceptibility and in the IFNbeta treatment response in a group of 147 patients ... -
IFNAR1 and IFNAR2 polymorphisms confer susceptibility to multiple sclerosis but not to interferon-beta treatment response.
Leyva-Fernández, Laura; Fernández-Fernández, Óscar; Fedetz, María; Blanco, Eva; Fernández, Victoria E.; Oliver-Martos, Begoña; León, Antonio; Pinto-Medel, María Jesús; Mayorga Mayorga, Cristobalina; Guerrero, Miguel; Luque, Gloria; Alcina, Antonio; Matesanz, Fuencisla[et al.] (Elsevier, 2005-04-22)
We investigated the role of three polymorphisms in the IFNAR1 (SNPs 18417 and -408) and IFNAR2 (SNP 11876) genes in multiple sclerosis (MS) susceptibility and in the IFNβ treatment response in a group of 147 patients and ... -
In vitro supporting diagnostic tools in plant‐food allergy.
Céspedes Lagos, José Antonio; Lebrón-Martín, Clara; García-Otón, Reyes; Delgado, María Jesús; Martín Astorga, María del Carmen; Pérez-Sánchez, Natalia Isabel; Gómez, Francisca; Torres-Jaén, María Josefa; Cañas, José Antonio; Aranda, Carlos José; Mayorga Mayorga, Cristobalina[et al.] (Wiley, 2023-04-06)
-
In vitro T-cell responses to beta-lactam drugs in immediate and nonimmediate allergic reactions.
Luque, Inmaculada; Leyva-Fernández, Laura; Torres-Jaén, María Josefa; Rosal, Manuel; Mayorga Mayorga, Cristobalina; Segura, José Manuel; Blanca, Miguel; Juárez, Carlos[et al.] (Wiley, 2008)
Background: Beta-Lactam drugs may induce both cellular and humoral allergic reactions, and there is evidence that T cells play an important role in the pathogenesis of these reactions. The aim of this work was to assess ... -
Influence of pore size in protein G'-grafted mesoporous silica nanoparticles as a serum pretreatment system for in vitro allergy diagnosis
Paris, Juan Luis; Monío, Cristina; Pérez-Moreno, Ana M.; Jurado-Escobar, Raquel; Bogas Herrera, Gádor; Fernández-Duarte, Tahía Diana; Montañez-Vega, María Isabel; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa[et al.] (Wiley, 2023)
Particles with the capacity to bind to immunoglobulin G (IgG) can be used for the purification of IgG or to process clinical samples for diagnostic purposes. For in vitro allergy diagnosis, the high IgG levels in serum can ... -
Interferon receptor expression in multiple sclerosis patients
Oliver-Martos, Begoña; Mayorga Mayorga, Cristobalina; Leyva-Fernández, Laura; León, Antonio; Luque, Gloria; C Lopez, Juan; Tamayo, Jose A; Pinto-Medel, Maria Jesús; De Ramón, Enrique; Blanco, Eva; Alonso, Ana; Fernández Fernández, Óscar[et al.] (Elsevier, 2006)
To determine the gene expression of IFNAR1, IFNAR2 and MxA protein and the association with IFNbeta treatment response in MS patients. MS patients treated with IFNbeta had a significant decrease in IFNAR1 and IFNAR2 ... -
Investigation of the diagnostic accuracy of basophil activation test for allergic phenotypes of rhinitis
(Wiley, 2024)Introduction: Basophil activation test (BAT) might be an alternative to nasal allergenchallenge (NAC) to identify the allergic etiology in rhinitis patients. Here, we investi-gate the diagnostic performance of BAT for ... -
LPS in combination with amoxicillin increases BAT sensitivity to amoxicillin IgE‐mediated hypersensitivity
Céspedes Lagos, José Antonio; Fernández-Santamaría, Rubén; Bogas Herrera, Gádor; Ariza Veguillas, Adriana; Doña, Inmaculada; Salas, María; Labella, Marina; Fernández-Duarte, Tahía Diana; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa; Frecha, Cecilia[et al.] (Wiley, 2024)
β-lactams (BLs), and among them, amoxicillin (AX) are the most current prescribed antibiotics to treat bacterial infections,1 and their use is related to an increasing prevalence of drug hypersensitivity reactions (DHRs),2 ... -
Neutralizing antibodies against IFN beta in patients with multiple sclerosis: a comparative study of two cytopathic effect tests (CPE) for their detection
Oliver-Martos, Begoña; Orpez, Teresa; Mayorga Mayorga, Cristobalina; Leyva-Fernández, Laura; López-Gómez, Carlos; Marín, Carmen; Luque, Gloria; Fernández Fernández, Óscar[et al.] (Elsevier, 2009)
The purpose of this study is to monitor the development of anti-natalizumab antibodies to evaluate their first appearance in multiple sclerosis patients, since their presence has been associated with a reduction in the ... -
New approaches for Basophil Activation Tests employing Dendrimeric Antigen-Silica Nanoparticle composites.
Calvo-Serrano, Silvia; Matamoros, Esther; Céspedes, José Antonio; Fernández-Santamaría, Rubén; Gil-Ocaña, Violeta; Pérez-Inestrosa, Ezequiel; Frecha, Cecilia; Montañez-Vega, María Isabel; Vida-Pol, Yolanda; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa[et al.] (MDPI, 2024-08-03)
In vitro detection of specific IgE bound to high-affinity receptor on basophils’ surface is 25 a widely used strategy for the evaluation of IgE-mediated immediate hypersensitivity reactions to 26 drugs. Due to the drug ... -
New Approaches in the Manufacture of Biomaterials for Betalactam Allergic Diagnose
Collado-Martín, Daniel; Pérez-de-Inestrosa-Villatoro, Ezequiel; Ruiz-Sanchez, Antonio Jesus; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa (2019-09-11)
Betalactams are the most widely utilized drugs against infections but are the primary cause of allergic reactions to antibiotic drugs. REF1 An accurate diagnosis of these allergic reactions to betalactams is crucial to ... -
Participación de los eicosanoides en la hipersensibilidad cruzada a anti-inflamatorios no esteroideos: mecanismos y base genética.
(UMA Editorial, 2024)Las reacciones de hipersensibilidad cruzada a anti-inflamatorios no esteroideos (RHC-AINEs) son la primera causa de hipersensibilidad a fármacos, siendo la urticaria/angioedema agudos (NIUA) la entidad clínica más frecuente. ... -
Perfil de sensibilización en pacientes con alergia a melocotón, y estudio de los cambios inmunológicos, eficacia y tolerancia a inmunoterapia específica con melocotón
(UMA Editorial, 2016)Aproximadamente el 2% de la población adulta es alérgica a alimentos, fundamentalmente a vegetales, siendo la familia de las Rosaceae la más frecuentemente implicada (1,2,3,4,5,6,7). La alergia a alimentos tiene un gran ... -
Silica Particle based nanocomposites for Specific IgE Determination to Betalactams
Matamoros Castellano, Esther; Gil-Ocaña, Violeta; Jiménez, Isabel M.; Mayorga Mayorga, Cristobalina; Doña, Inmaculada; Céspedes Lagos, José Antonio; Montañez-Vega, María Isabel; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel; Torres-Jaén, María Josefa[et al.] (2023)
Current immunoassays for diagnosing betalactam (BL) allergy have limited sensitivity and poor specificity. These include ImmunoCAP, the commercial immunoassay, and the radioallergosorbent test (RAST), a handmade test ... -
Study of binding and neutralising antibodies to interferon-β in two groups of relapsing-remitting multiple sclerosis patients.
Fernández Fernández, Óscar; Mayorga Mayorga, Cristobalina; Luque, Gloria; Guerrero, Miguel; Guerrero, Rocío; Leyva-Fernández, Laura; León-Martín, Antonio; Blanca, Miguel[et al.] (Springer Nature, 2001)
Interferon (IFN)-β is generally considered an effective treatment for multiple sclerosis (MS); however, some patients do not respond to this therapy, possibly due to the production of neutralising antibodies (NAB) which ... -
Synthetic antigenic determinants of clavulanic acid induce dendritic cell maturation and specific T cell proliferation in patients with immediate hypersensitivity reactions
Fernández-Santamaría, Rubén; Bogas Herrera, Gádor; Montañez-Vega, María Isabel; Ariza Veguillas, Adriana; Salas, María; Céspedes Lagos, José Antonio; Labella, Marina; Paris, Juan Luis; Pérez-Sánchez, Natalia Isabel; Pérez-de-Inestrosa-Villatoro, Ezequiel; Vida-Pol, Yolanda; Fernández-Duarte, Tahía Diana; Mayorga Mayorga, Cristobalina[et al.] (Wiley, 2022-05-24)
Background Immediate drug hypersensitivity reactions (IDHRs) to clavulanic acid (CLV) have increased in the last decades due to a higher consumption alongside amoxicillin (AX). Due to its chemical instability, diagnostic ... -
The value of the basophil activation test in the evaluation of patients reporting allergic reactions to the BNT162b2 mRNA COVID-19 vaccine
Labella, Marina; Céspedes Lagos, José Antonio; Doña, Inmaculada; Shamji, Mohamed H.; Agache, Ioana; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa[et al.] (Wiley, 2021-10-24)
-
Usefulness of myeloid dendritic cells in cellular in vitro assays for evaluating immediate hypersensitivity reactions to betalactams.
Fernández-Santamaría, Rubén; Ariza Veguillas, Adriana; Bogas Herrera, Gádor; Salas, María; Calvo-Serrano, Silvia; Frecha, Cecilia; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa; Fernández-Duarte, Tahía Diana[et al.] (2023)
Introduction Dendritic cells (DCs) are the most potent antigen presenting cells (APCs) with an important role detecting, processing, and presenting antigens to T cells. The analysis of maturation after in vitro stimulation ...