Listar por autor "Borroto-Escuela, Dasiel"
Mostrando ítems 21-40 de 47
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Galanin N-Terminal fragment (1-15) induces a stronger effect than Galanin in depression- and anxiety- like related behavioural tests in rats.
Millón-Peñuela, Carmelo
; Narváez-Peláez, Manuel; Flores-Burgess, Antonio; Parrado-Romero, Concepción; Puigcerver-Martínez, Araceli; Coveñas, Rafael; Santín-Núñez, Luis Javier; Borroto Escuela, Dasiel Óscar; Fuxe, Kjell; Narváez-Bueno, José Ángel; Díaz-Cabiale, Zaida[et al.] (2014-07-16)
Galanin (GAL) and GAL Receptors are implicated in anxiety- and depression- related behaviours. The GAL N-terminal fragment (1-15) [GAL(1-15)] also induces depressant- and anxiogenic- like actions. In this work, we have ... -
Galanin receptor 2 modifies neuropeptide Y Y1 receptor internalization and β-Arrestin recruitment
Narváez-Peláez, Manuel; Borroto Escuela, Dasiel Óscar; Millón-Peñuela, Carmelo; Flores-Burgess, Antonio; Gago-Calderón, Belén; Santín-Núñez, Luis Javier; Fuxe, Kjell; Narváez-Bueno, José Ángel; Díaz-Cabiale, Zaida[et al.] (2015-10-05)
We have recently described a Galanin receptor 2(GALR2) and Neuropeptide Y Y1 receptor(NPYY1R) interaction at behavioural, cellular and receptor levels through GALR2/NPYY1R heterodimers. The aim of this work was to study ... -
Galanin receptor 2-neuropeptide Y Y1 receptor interactions in the amygdala lead to increased anxiolytic actions
Narváez-Peláez, Manuel; Millón-Peñuela, Carmelo; Borroto Escuela, Dasiel Óscar; Flores-Burgess, Antonio; Santín-Núñez, Luis Javier; Parrado-Romero, Concepción; Gago-Calderón, Belén; Puigcerver-Martínez, Araceli; Fuxe, Kjell; Narváez-Bueno, José Ángel; Díaz-Cabiale, Zaida[et al.] (Springer Nature, 2014-05-20)
Galanin (GAL) and Neuropeptide Y (NPY) are neuropeptides involved in behaviors associated with anxiety. Both neuropeptides interact in several central functions. However, the potential behavioral and cellular ... -
Galanin receptor 2-neuropeptide Y Y1 receptor interactions in the dentate gyrus are related with antidepressant-like effects.
Narváez-Peláez, Manuel; Borroto Escuela, Dasiel Óscar; Millón-Peñuela, Carmelo; Gago-Calderón, Belén; Flores-Burgess, Antonio; Santín-Núñez, Luis Javier; Fuxe, Kjell; Narváez-Bueno, José Ángel; Díaz-Cabiale, Zaida[et al.] (Springer Nature, 2015-12-14)
Galanin (GAL) and the NPYY1 agonist play a role in mood regulation and both neuropeptides interact in several central functions. The present study examined the interaction between Galanin receptor 2 (GALR2) and Neuropeptide ... -
Galanin receptor/neuropeptide y recptor interactions in the central nervous system
Díaz-Cabiale, Zaida; Narváez-Peláez, Manuel; Millón-Peñuela, Carmelo; Borroto Escuela, Dasiel Óscar; Flores-Burgess, Antonio; Santín-Núñez, Luis Javier; Parrado-Romero, Concepción; Puigcerver-Martínez, Araceli; Fuxe, Kjell; Narváez-Bueno, José Ángel[et al.] (2013-11-20)
The presence of Galanin and Neuropeptide Y and/or their receptors in many relevant brain regions related to learning and memory, mood, cardiovascular control and food intake implies that Galanin, and Neuropeptide Y may ... -
Galanin/ Neuropeptide Y Y1 receptor interaction at the cellular and receptor level in the amygdala
Narváez-Peláez, Manuel; Millón-Peñuela, Carmelo; Flores-Burgess, Antonio; Parrado-Romero, Concepción; Puigcerver-Martínez, Araceli; Borroto Escuela, Dasiel Óscar; Fuxe, Kjell; Díaz-Cabiale, Zaida; Narváez-Bueno, José Ángel[et al.] (2013-11-18)
Galanin (GAL) interacts functionally with Neuropeptide Y Y1 receptor (Y1) in the nucleus tractus solitarius and the arcuate nucleus. Since GAL and Y1 participate in mood disorders, the aim of this work was to analyze GAL/Y1 ... -
GALR1/GALR2 Knockdown rats block the Depression and Anxiogenic effects induced by GAL(1-15): The Heterodimer GALR1/GALR2 as a target of GAL(1-15).
Millón-Peñuela, Carmelo; Flores-Burgess, Antonio; Narváez-Peláez, Manuel; Borroto Escuela, Dasiel Óscar; Santín-Núñez, Luis Javier; Parrado-Romero, Concepción; Narváez-Bueno, José Ángel; Fuxe, Kjell; Díaz-Cabiale, Zaida[et al.] (2015-10-06)
The Galanin N-terminal fragment (1-15) [GAL(1-15)] induces depressant- and anxiogenic- like actions. In this work, we have studied the role of GALR2 and GALR1 on the effects of GAL(1-15) in the Forced Swimming Test (FST) ... -
GALR2/NPYY1R heterodimers interact at receptor level in the dentate gyrus of the hippocampus in rats
Narváez-Peláez, Manuel; Borroto Escuela, Dasiel Óscar; Millón-Peñuela, Carmelo; Flores-Burgess, Antonio; Gago-Calderón, Belén; Santín-Núñez, Luis Javier; Fuxe, Kjell; Narváez-Bueno, José Ángel; Díaz-Cabiale, Zaida[et al.] (2016-09-26)
Previously, we have described Galanin(GAL) and Neuropeptide Y Y1(NPYY1) interactions at behavioural, cellular and receptor levels through GALR2/NPYY1R heterodimers in the amygdala. The aim of this work was to study GAL/NPYY1R ... -
Immunohistochemical C-FOS expression and autoradiography to study galnin/neuropeptide y Y1 receptor-receptor interactions in the amygdala
Narváez-Peláez, Manuel; Millón-Peñuela, Carmelo; Flores-Burgess, Antonio; Santín-Núñez, Luis Javier; Parrado-Romero, Concepción; Puigcerver-Martínez, Araceli; Borroto Escuela, Dasiel Óscar; Fuxe, Kjell; Díaz-Cabiale, Zaida; Narváez-Bueno, José Ángel[et al.] (2013-10-02)
We have shown Galanin(GAL)/Neuropeptide Y Y1 receptor(Y1) interactions in the nucleus tractus solitarius and the arcuate nucleus. Since both peptides play an important role in mood disorders, the aim of this work was to ... -
Improvement on hippocampal neuroproliferation through galanin and neuropeptide y y1 receptor agonist interaction
Narváez-Peláez, Manuel; Santín-Núñez, Luis Javier; Tif, Maria; Fuxe, Kjell; Borroto Escuela, Dasiel Óscar (2019-09-11)
Neurogenesis persists in the hippocampus throughout the lifespan in a wide variety of species including humans. Within the dentate gyrus of the hippocampus, the subgranular zone (SGZ) is maintained as a stem cell niche. ... -
Influence of limb dominance on body and jump asymmetries in elite female handball.
Carrasco-Fernández, Laura; García-Sillero, Manuel; Jurado‑Castro, José Manuel; Borroto Escuela, Dasiel Óscar; García-Romero, Jerónimo; Benítez-Porres, Javier[et al.] (Nature Research, 2023-10-07)
Handball is a team sport subjected to asymmetric actions that require high physical capacity demands on players. The development of large asymmetries could negatively affect sports performance. However, few studies have ... -
Intranasal Delivery of Galanin 2 and Neuropeptide Y1 Agonists Enhanced Spatial Memory Performance and antidepressant e!ects through Neuronal Precursor Cells Proliferation in the hippocampus
Borroto Escuela, Dasiel Óscar; Mirchandani-Duque, Marina; Fores-Pons, Ramón; Pita-Rodríguez, Mariana; Zamorano-González, Pablo; Barbancho-Fernández, Miguel Ángel; García-Casares, Natalia; Fuxe, Kjell; Narváez-Peláez, Manuel[et al.] (2022-07-07)
Neuropeptide Y(NPY) Y1 receptor (Y1R) and galanin (GAL) receptor 2 (GALR2) interact in brain regions responsible for learning and memory processes, emphasizing the hippocampus. The current study assesses the sustained ... -
Intranasal Delivery of Galanin 2 and Neuropeptide Y1 Agonists Enhanced Spatial Memory Performance and Neuronal Precursor Cells Proliferation in the Dorsal Hippocampus in Rats.
Borroto-Escuela, Dasiel; Fores, Ramón; Pita-Rodríguez, Mariana; Barbancho-Fernández, Miguel Ángel; Zamorano-González, Pablo; García-Casares, Natalia; Fuxe, Kjell; Narváez-Peláez, Manuel[et al.] (Frontiers, 2022)
A need for new therapeutic approaches are necessary for dementia conditions and memory deficits of different origins, such as Alzheimer’s disease. There is complex pathophysiological mechanisms involved, affecting adult ... -
Long- term enhancements in antidepressant efficacy and neurogenesis: Effects of intranasal co- administration of neuropeptide Y 1 receptor (NPY1R) and galanin receptor 2 (GALR2) agonists in the ventral hippocampus
Rasiel, Beltran-Casanueva; Aracelis, Hernández-García; Serrano-Castro, Pedro Jesús; Sánchez-Pérez, José Andrés; Barbancho-Fernández, Miguel Ángel; García-Casares, Natalia; Fuxe, Kjell; Borroto Escuela, Dasiel Óscar; Narváez-Peláez, Manuel[et al.] (WILEY, 2024-04-15)
This study evaluates the sustained antidepressant- like effects and neurogenic potential of a 3- day intranasal co- administration regimen of galanin receptor 2 (GALR2) agonist M1145 and neuropeptide ... -
NPYY1 /Galanin 2 heterodimers in the amygdala: a proximity ligation assay study
Narváez-Peláez, Manuel; Millón-Peñuela, Carmelo; Borroto Escuela, Dasiel Óscar; Flores-Burgess, Antonio; Santín-Núñez, Luis Javier; Parrado-Romero, Concepción; Gago-Calderón, Belén; Puigcerver-Martínez, Araceli; Fuxe, Kjell; Narváez-Bueno, José Ángel; Díaz-Cabiale, Zaida[et al.] (2014-07-10)
We have shown that Galanin(GAL) interacts with Neuropeptide Y Y1 receptor(Y1) at behavioural, cellular and receptor levels in the Amygdala. Since both peptides play an important role in mood disorders, the aim of this work ... -
Nuevas propuestas de integración de competencias mediante la evaluación formativa de forma transversal y TIC para atender a la diversidad motivacional
Narváez-Peláez, Manuel; Morales-Rodríguez, Francisco Manuel; Morales Rodriguez, Ana Maria; Maroto Blanco, José Manuel; Borroto Escuela, Dasiel Óscar (2019-11-27)
Los estudiantes son capaces y su potencial de aprendizaje es ilimitado, aunque hay claras diferencias entre los distintos alumnos. De ahí que el profesorado actúe apoyando, guiando, motivando y dinamizando el proceso de ... -
On the balance of D2R-MOR and D4R-MOR in the dorsal and ventral striatum. Putative link to morphine dependence and addiction
Fores-Pons, Ramón; Narváez-Peláez, Manuel; Vasudevan, Lakshmi; Crespo-Ramírez, Minerva; Rivera-Ramírez, Alicia; Pérez de la Mora, Miguel; Stove, Christophe; Fuxe, Kjell; Borroto Escuela, Dasiel Óscar[et al.] (8th Mediterranean Neuroscience Society (MNS), 2022-05-30)
The widespread distribution of heteroreceptor complexes with allosteric receptor-receptor interactions in the CNS represents a novel integrative molecular mechanism in the plasma membrane of neurons and glial cells. It was ... -
On the role of GPCR heteroreceptor complexes neuromodulation of the Claustrum
(8th Mediterranean Neuroscience Society (MNS), 2022-05-30)G protein-coupled receptors (GPCRs) modulate the synaptic glutamate and GABA transmission of the claustrum. Our work focused on the transmitter-receptor relationships in the claustral catecholamine system and receptor-receptor ... -
On the Role of Neuropeptide Y Receptor 1 (NPY1R)-Galanin Receptor 2 (GALR2) Heteroreceptor Complexes in Enhancing Adult Hippocampal Neurogenesis and Cognitive Function
(UMA Editorial, 2024-09)This PhD thesis investigates the roles of Neuropeptide Y receptor 1 (NPY1R) homo- and heteroreceptor complexes, specifically NPY1R- galanin receptor 2 (GALR2) heteroreceptor complexes, within the Central Nervous System ... -
On the role of the balance of G protein-coupled receptor (GPCR) homo and heteroreceptor complexes and their integration of signals in neurons and astroglia. Relevance for brain disorders
(UMA Editorial, 2022)There exists substantial evidence for the existence of G protein-coupled receptor (GPCR) homo and heteroreceptor complexes with allosteric receptor-receptor interactions in the Central Nervous System (CNS). The formation ...