Listar por autor "Borrego-García, Juan José"
Mostrando ítems 21-40 de 62
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Evaluation of gilthead seabream (Sparus aurata) immune response after LCDV DNA vaccination
Leiva-Rebollo, Rocío; Castro-López, María Dolores
; Borrego-García, Juan José; Labella Vera, Alejandro Manuel (2019-10-07)
A DNA vaccine against Lymphocystis Disease Virus (LCDV) was developed and its protective efficacy in gilthead seabream (Sparus aurata) has been established. The aim of the present study is the evaluation of immune-related ... -
Evaluation of Gilthead Seabream (Sparus aurata) Immune Response after LCDV-Sa DNA Vaccination
Leiva Rebollo, Rocío; Castro-López, María Dolores; Moreno García, Patricia; Borrego-García, Juan José; Labella Vera, Alejandro Manuel (MDPI, 2021-05-29)
Lymphocystis disease is the main viral pathology in gilthead seabream aquaculture. Currently, there are no treatments or vaccines to control this disease, thus our main goal was to construct a DNA vaccine that can be used ... -
Evaluation of immune response after LCDV-Sa infection in DNA-vaccinated gilthead seabream
Leiva-Rebollo, Rocío; Gémez-Mata, Juan; Castro-López, María Dolores; Borrego-García, Juan José; Labella Vera, Alejandro Manuel (2021)
The immune-related gene expression in vaccinated gilthead seabream after Lymphocystis Disease Virus 3 (LCDV-Sa) infection was analysed by using an OpenArray based on TaqMan qPCR. The DNA vaccine used in this study encodes ... -
Evaluation of the immune response in betanodavirus-vaccinated gilthead seabream.
Gémez-Mata, Juan; Leiva-Rebollo, Rocío; Moreno-García, Patricia; Bandín Matos, Isabel; Borrego-García, Juan José; Labella Vera, Alejandro Manuel; Castro-López, María Dolores[et al.] (2023)
An inactivated vaccine has been developed using a RGNNV/SJNNV reassortant strain isolated from Senegalese sole, which confers moderate protection against the homologous viral strain in sole juveniles. The aim of this study ... -
First isolation of Photobacterium damselae ssp. damselae from cultured redbanded seabream, Pagrus auriga Valenciennes, in Spain
Labella Vera, Alejandro Manuel; Alonso-Sánchez, María del Carmen; Infante, Carlos; Cardenas, Salvador; López-Romalde, Sonia; Machado, Manuel; Borrego-García, Juan José[et al.] (Blackwell Publishing Ltd, 2006-03-14)
This is the first report of the isolation of P. damselae ssp. damselae from redbanded seabream, a sparid fish newly cultured in southern Spain. A low variability in the biochemical profile among the P. damselae ssp. ... -
Genetic estimates and immune response associated with the Lymphocystis Disease Virus (LCDV) in marine fish
(UMA Editorial, 2021-03-10)El Virus de la Enfermedad de Linfocistis (LCDV) es una agente infeccioso de distribución cosmopolita que afecta a un amplio espectro de peces, incluyendo la dorada (Sparus aurata) y el lenguado senegalés (Solea senegalensis), ... -
Genomic analysis of the marine fish pathogen Photobacterium damselae subsp. piscicida: Insertion sequences proliferation is associated with chromosomal reorganisations and rampant gene decay.
Balado, Miguel; Benzekri, Hicham; Labella Vera, Alejandro Manuel; Claros-Díaz, Manuel Gonzalo; Manchado, Manuel; Borrego-García, Juan José; Osorio, Carlos; Lemos, Manuel[et al.] (Elsevier, 2017)
Photobacterium damselae subsp. piscicida (Pdp) is an intracellular fish pathogen that causes photobacteriosis, a disease proven deadly in farmed fish worldwide. This work focuses on the analysis of genome sequences, ... -
Gilthead seabream (Sparus aurata) Mx proteins show positive and negative synergy in their antiviral activity
Fernández-Trujillo, M. Alejandra; García-Rosado, Esther; Alonso-Sánchez, María del Carmen; Borrego-García, Juan José; Álvarez-Herrero, María del Carmen; Béjar-Alvarado, Julia[et al.] (2014-10-07)
Due to their direct antiviral activity, Mx proteins play a main role in the response mediated by the type I interferon against viral infections. The study of the farmed fish gilthead seabream Mx genes is specially interesting, ... -
High incidence of antibiotic multi-resistant bacteria in coastal areas dedicated to fish farming
(Elsevier, 2013-05-15)Marine bacteria exposed to antibiotics in fish farms can acquire antimicrobial resistance by mobile genetic elements and horizontal gene transfer. A total of 872 autochthonous marine bacterial strains was isolated from ... -
Human gut microbiome, diet, and mental disorders.
(Springer, 2024-04-01)Diet is one of the most important external factor shaping the composition and metabolic activities of the gut microbiome. The gut microbiome plays a crucial role in host health, including immune system development, nutrients ... -
Immune gene expression in gilthead seabream (Sparus aurata) after Lymphocystis disease virus (LCDV‐Sa) challenge resulting in asymptomatic infection
Leiva Rebollo, Rocío; Labella Vera, Alejandro Manuel; Borrego-García, Juan José; Castro-López, María Dolores (Oxford Academic, 2020-01-01)
Aims: To determine the immune gene expression response of gilthead seabream (Sparus aurata) that is experimentally infected with the lymphocystivirus LCDV-Sa. Methods and Results: Viral DNA and transcripts were detected ... -
Immune gene expression in gilthead seabream after nervous necrosis virus (NNV) challenge
Gémez-Mata, Juan; Leiva-Rebollo, Rocío; Moreno-García, Patricia; Bandín Matos, Isabel; Borrego-García, Juan José; Labella Vera, Alejandro Manuel; Castro-López, María Dolores[et al.] (2022-09)
Viral nervous necrosis (VNN) is a disease that affects farmed fish worldwide. Its etiologic agent is the nervous necrosis virus (NNV), genus Betanodavirus, family Nodaviridae. NNV are small and non-enveloped viruses with ... -
Immune response of DNA vaccinated-gilthead seabream against LCDV-Sa infection: relevance of the inflammatory process.
Leiva-Rebollo, Rocío; Gémez-Mata, Juan; Castro-López, María Dolores; Borrego-García, Juan José; Labella Vera, Alejandro Manuel (2023)
Lymphocystis disease is one of the main viral pathologies affecting cultured gilthead seabream in the Mediterranean area. Recently, we have developed a DNA-vaccine based on the major capsid protein of the Lymphocystis ... -
Immune response of gilthead seabream (Sparus aurata) after experimental infection with lymphocystis disease virus (LCDV-Sa)
Leiva-Rebollo, Rocío; Labella Vera, Alejandro Manuel; Castro-López, María Dolores; Borrego-García, Juan José (2019-07-29)
Lymphocystis disease (LCD) is caused by the lymphocystis disease virus (LCDV) (family Iridoviridae), affecting more than 150 fish species from both marine and freshwater environments. A few studies have been focused on the ... -
Immune response of gilthead seabream infected with wild and mutant nervous necrosis virus reassortants.
Gémez-Mata, Juan; Leiva-Rebollo, Rocío; Moreno-García, Patricia; Borrego-García, Juan José; Labella Vera, Alejandro Manuel; Castro-López, María Dolores[et al.] (2023)
Viral nervous necrosis (VNN) is a disease that affects farmed fish worldwide. Its etiologic agent is the nervous necrosis virus currently classified into 4 species: SJNNV, RGNNV, TPNNV and BFNNV. In Southern Europe, ... -
Immune Response of Senegalese Sole against Betanodavirus Mutants with Modified Virulence.
Gémez Mata, Juan; Souto, Sandra; Bandin, Isabel; Alonso-Sánchez, María del Carmen; Borrego-García, Juan José; Labella Vera, Alejandro Manuel; García-Rosado, Esther[et al.] (MDPI, 2021-10-27)
Nervous necrosis virus (NNV), genus Betanodavirus, the etiological agent of the viral encephalopathy and retinopathy (VER), presents a genome with two positive-sense single-stranded RNA segments. Striped jack nervous ... -
Immune response of Senegalese sole and gilthead seabream after vaccination with an inactivated vaccine against betanodavirus.
Gémez-Mata, Juan; Leiva-Rebollo, Rocío; Moreno-García, Patricia; Bandín Matos, Isabel; Borrego-García, Juan José; Labella Vera, Alejandro Manuel; Castro-López, María Dolores[et al.] (2024)
Nervous necrosis virus (NNV) (genus Betanodavirus, family Nodaviridae) is the etiologic agent of viral encephalopathy and retinopathy (VER). This virus is classified into four species: SJNNV, RGNNV, TPNNV and BFNNV. In ... -
Immune response of vaccinated juvenile gilthead seabream (Sparus aurata) after LCDV-Sa infection
Leiva-Rebollo, Rocío; Gémez-Mata, Juan; Borrego-García, Juan José; Castro-López, María Dolores; Labella Vera, Alejandro Manuel (2022-09)
Lymphocystis disease is one of the main viral pathologies affecting cultured gilthead seabream in the Mediterranean area. In our group, a DNA-vaccine has been developed based on the major capsid protein (MCP) of the ... -
Immunogene expression analysis in betanodavirus infected-Senegalese sole using an OpenArray® platform.
Gémez-Mata, Juan; Labella Vera, Alejandro Manuel; Bandín Matos, Isabel; Borrego-García, Juan José; García-Rosado, Esther (ELSEVIER, 2021-03-30)
The transcriptomic response of Senegalese sole (Solea senegalensis) triggered by two betanodaviruses with different virulence to that fish species has been assessed using an OpenArray® platform based on TaqMan™ quantitative ... -
In vitro viral coexistence decreases Striped Jack Nervous Necrosis Virus (SJNNV) but favours Red-spotted Grouper Nervous Necrosis Virus (RGNNV) replication
López-Jimena, Benjamín; Alonso-Sánchez, María del Carmen; Infante, Carlos; Castro-López, María Dolores; Borrego-García, Juan José; García-Rosado, Esther[et al.] (European Association of Fish Pathologists, 2013)
In this study, several assays have been performed to characterise the effect of the RGNNV-SJNNV coexistence (coinfection and superinfection) on the replication of each genotype on E-11 cells.The results obtained showed the ...