Listar por autor "Santos-Ruiz, Leonor"
Mostrando ítems 21-27 de 27
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Oridonin enhances antitumor effects of doxorubicin in human osteosarcoma cells
Kazantseva, Liliya; Becerra-Ratia, José
; Santos-Ruiz, Leonor (Springer, 2021-08-24)
Background Doxorubicin is the chemotherapeutic drug of choice in osteosarcoma treatment, but its cumulative administration causes dilated cardiomyopathy. Combination therapy represents a potential strategy to reduce the ... -
Osteogenic molecules for clinical applications: Improving the BMP-collagen system
Arrabal-García, Pilar María; Visser, Rick; Santos-Ruiz, Leonor; Becerra-Ratia, José; Cifuentes-Rueda, Manuel (Sociedad de Biología de Chile, 2013)
Among the osteogenic growth factors used for bone tissue engineering, bone morphogenetic proteins (BMPs) are the most extensively studied for use in orthopaedic surgery. BMP-2 and BMP-7 have been widely investigated for ... -
RGD-dendritic structures on titanium alloy. Influence in the relationship between bone cells and the metal surface
Molina, Noemí; González-Luque, Ana; Becerra-Ratia, José; Santos-Ruiz, Leonor; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2019-09-18)
Prosthetic implants are used in surgical procedures to replace a joint (hip or knee) allowing the functional recovery of the patient. Prostheses are usually made of titanium alloys. However, the lack of chemical and ... -
Squamous cell carcinoma related with dental implants. A clinical cases report.
Granados, Francisco; Santos-Ruiz, Leonor; Contreras, Marian; Mellado, José; Martín, Gregorio; Bermudo, Lucas; Ruiz, Francisco; Aguilar, Yolanda; Yáñez, Ignacio; Yáñez, Ignacio[et al.] (Medicina Oral S.L., 2020-01)
One third of all cases of head and neck carcinoma (CA) concern the oral mucosa. The use of dental implants (DI) for dental rehabilitation is widely extended. However, a few studies have reported some cases with neoplasic ... -
Surface nitridation improves bone cell response to melt-derived bioactive silicate/borosilicate glass composite scaffolds
Orgaz, Felipe; Dzika, A.; Szycht, O.; Amat, Daniel; Barba, Flora; Becerra-Ratia, José; Santos-Ruiz, Leonor[et al.] (Elsevier, 2016-01-01)
Novel bioactive amorphous glass-glass composite scaffolds (ICIE16/BSG) with interconnected porosity have been developed. Hierarchically interconnected porous glass scaffolds were prepared from a mixture of two melt-derived ... -
Synergistic effect of Si-hydroxyapatite coating and VEGF adsorption on Ti6Al4V-ELI scaffolds for bone regeneration in an osteoporotic bone environment
Izquierdo-Barba, Isabel; Santos-Ruiz, Leonor; Becerra-Ratia, José; Feito, M.J.; Fernández-Villa, D.; Serrano, M.C.; Díaz-Güemes, I.; Fernández-Tomé, B.; Enciso, S.; Sánchez-Margallo, F.M.; Monopoli, Donato; Alfonso, H.; Portolés, María Teresa; Arcos, Daniel; Vallet-Regí, M.[et al.] (Elsevier, 2019-01-01)
The osteogenic and angiogenic responses to metal macroporous scaffolds coated with silicon substituted hydroxyapatite (SiHA) and decorated with vascular endothelial growth factor (VEGF) have been evaluated in vitro and in ... -
Traditional Medicinal Plants as a Source of Inspiration for Osteosarcoma Therapy.
Kazantseva, Liliya; Becerra-Ratia, José; Santos-Ruiz, Leonor (MDPI, 2022-08-06)
Osteosarcoma is one of the most common types of bone cancers among paediatric patients. Despite the advances made in surgery, chemo-, and radiotherapy, the mortality rate of metastatic osteosarcoma remains unchangeably ...