Listar por autor "Vida-Pol, Yolanda"
Mostrando ítems 21-40 de 43
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Multiepitope Dendrimeric Antigen-Silica particle composites as nano-based platforms for specific recognition of IgEs
Gil-Ocaña, Violeta; Jimenez, Isabel M.; Mayorga, Cristobalina; Doña, Inmaculada; Cespedes, Jose A.; Montañez, Maria I.; Vida-Pol, Yolanda
; Torres, Maria J.; Perez-Inestrosa, Ezequiel[et al.] (Frontiers, 2021)
β-lactam antibiotics (BLs) are the drugs most frequently involved in drug hypersensitivity reactions. However, current in vitro diagnostic tests have limited sensitivity, partly due to a poor understanding of in vivo ... -
New acyl hydrazones with promising photophysical properties
Hydrazones have become of great interest for the scientific community due to their promising chemical properties and biological activities. In this group of compounds, the acyl or aryl hydrazones, that are Schiff bases ... -
New approaches for Basophil Activation Tests employing Dendrimeric Antigen-Silica Nanoparticle composites.
Calvo-Serrano, Silvia; Matamoros, Esther; Céspedes, José Antonio; Fernández-Santamaría, Rubén; Gil-Ocaña, Violeta; Pérez-Inestrosa, Ezequiel; Frecha, Cecilia; Montañez-Vega, María Isabel; Vida-Pol, Yolanda; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa[et al.] (MDPI, 2024-08-03)
In vitro detection of specific IgE bound to high-affinity receptor on basophils’ surface is 25 a widely used strategy for the evaluation of IgE-mediated immediate hypersensitivity reactions to 26 drugs. Due to the drug ... -
New Insights into Acylhydrazones E/Z isomerization: An Experimental and Theoretical Approach.
Fernández-Palacios, Sara; Matamoros, Esther; Morato Rojas, Isabel; López Navarrete, Juan T.; Ruiz-Delgado, María del Carmen; Vida-Pol, Yolanda; Perez-Inestrosa, Ezequiel[et al.] (MDPI, 2023)
A family of acylhydrazones have been prepared and characterized with the aim of investigating their potential as information storage systems. Their well stablished synthetic methodologies allowed the preparation of seven ... -
One and two-photons excitation of aminonaphthalimide–bodipy dyads: biological application
Vida-Pol, Yolanda (2014-07-25)
Boron dipyrromethene (BODIPY) dyes are commonly commercialized chromophores that have attracted immense interest as versatile tools in biological chemistry. However, the generally very small Stokes shifts of BODIPY dyes ... -
Preparation of Dendrimeric antigen-silica particle composites
The desing and synthesis of new materials for biomedical applications is a high-priority research topic in a great number of biomedical areas. Moreover, advances in the fabrication of these materials are of growing interest ... -
Preparation, photophysical properties and cell image of Naphthalimide-based fluorescent nanostructures for biomedical applications: BAPAD dendrimeric antigens and silica nanoparticles
Mesa, Pablo; Collado-Martín, Daniel; Vida-Pol, Yolanda; Nájera-Albendín, Francisco; Pérez-de-Inestrosa-Villatoro, Ezequiel (2014-07-17)
We present here the synthesis and characterization of BAPAD [1] fluorescent Dendrimeric-Antigens (DeAn), to be applied in basophil activation as a test to detect drug allergy reactions. A second generation BAPAD dendrimer ... -
Pt(II)-dendrimers as bio-imaging marker for bacteria in two-photon excitation microscopy
Vida-Pol, Yolanda; Molina, Noemi; Cnudde, Marvin; Guadix-Domínguez, Juan Antonio; Pérez-Pomares, José María; Strassert, Cristian A.; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2019-07-25)
The use of luminescent markers based on metal complexes in two-photon excitation microscopy techniques are of great interest in the field of bioimaging. However, despite the excellent luminescent properties of Pt(II) ... -
Recognition of multiepitope dendrimeric antigens by human immunoglobulin E.
Montañez-Vega, María Isabel; Nájera-Albendín, Francisco; Mayorga, Cristobalina; Ruiz-Sánchez, Antonio Jesús; Vida-Pol, Yolanda; Collado-Martín, Daniel; Blanca, Miguel; Torres-Jaén, María Josefa; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (Elsevier, 2015-02-07)
In vitro drug allergy tests have limited sensitivity, partly due to a poor understanding of the immunological recognition of in vitro drug–protein conjugates. We have designed and synthesized multivalent mono- and bi-epitope ... -
RGD peptide on Dendrimer surfaces Affects Mesenchymal Stem Cells Adhesion
Vida-Pol, Yolanda; Molina, Noemi; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Lagunas, Anna; Claros-Gil, Silvia; Becerra-Ratia, José; Andrades-Gómez, José Antonio; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2016-04-07)
Mesenchymal stem cells (MSCs) are promising candidates for a range of tissue regeneration applications. Adequate scaffolds are necessary for their application in vivo, where interactions between cells and the surface ... -
RGD-dendritic structures on titanium alloy. Influence in the relationship between bone cells and the metal surface
Molina, Noemí; González-Luque, Ana; Becerra-Ratia, José; Santos-Ruiz, Leonor; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2019-09-18)
Prosthetic implants are used in surgical procedures to replace a joint (hip or knee) allowing the functional recovery of the patient. Prostheses are usually made of titanium alloys. However, the lack of chemical and ... -
Silica Particle based nanocomposites for Specific IgE Determination to Betalactams
Matamoros Castellano, Esther; Gil-Ocaña, Violeta; Jiménez, Isabel M.; Mayorga Mayorga, Cristobalina; Doña, Inmaculada; Céspedes Lagos, José Antonio; Montañez-Vega, María Isabel; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel; Torres-Jaén, María Josefa[et al.] (2023)
Current immunoassays for diagnosing betalactam (BL) allergy have limited sensitivity and poor specificity. These include ImmunoCAP, the commercial immunoassay, and the radioallergosorbent test (RAST), a handmade test ... -
Síntesis eficiente de estructuras dendriméricas amino terminales para aplicaciones biomédicas
(UMA Editorial, 2023)Un dendrímero se describe generalmente como una macromolécula que se caracteriza por poseer una estructura tridimensional altamente ramificada, ordenada y controlada, lo que le proporciona un alto grado de funcionalidad ... -
Sistema fluorescentes multifotónicos con aplicaciones en bioimagen
Collado-Martín, Daniel; Pérez-de-Inestrosa-Villatoro, Ezequiel; Vida-Pol, Yolanda; Nájera-Albendín, Francisco; Ramon, Patricia; Pischel, Uve[et al.] (2013-09-20)
Los colorantes y las sondas fluorescentes son componentes clave en el estudio de muestras biológicas mediante microscopía de fluorescencia. Mientras que muchos colorantes fluorescentes disponibles comercialmente han sido ... -
Slightly congested amino terminal dendrimers. The synthesis of amide-based stable structures on a large scale.
Morgado Benítez, Anjara; Nájera-Albendín, Francisco; Lagunas, Anna; Samitier, Josep; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (Royal Society of Chemistry, 2021-08-17)
Nowadays, amino terminal dendrimers are appealing materials for biological applications due to their multivalence and the versatile conjugation of the amino groups. However, the high reactivity of these terminal groups can ... -
Syntehsis and use of dendrimeric structures as a tool in biomedicine
Pérez-de-Inestrosa-Villatoro, Ezequiel; Vida-Pol, Yolanda; Molina, Noemi; Morgado, Anjara; Nájera-Albendín, Francisco (2019-10-28)
Specific cell interactions of surfaces grafted dendrimers have been applied to the study of cell adhesion. We have studied also the application of dendrimer-based uneven nanopatterns to evaluate the local RGD surface density ... -
Synthesis and Biomedical aplications of BAPAD: Bisaminoalkylpolyamide Dendrimers
Pérez-de-Inestrosa-Villatoro, Ezequiel; Ruiz-Sanchez, Antonio Jesus; Vida-Pol, Yolanda; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Mesa, Pablo; Morato, Isabel; Barbero, Nekane[et al.] (2014-02-06)
A new class of Dendrimeric Systems (Dendrimers and Dendrons) and the study of their properties in molecular recognition processes are presented. These Dendrimers (BAPAD: BisAminoalkylPolyAmideDendrimers), are designed to ... -
Synthesis of all-aliphatic polyamide dendrimers based on a 3,3′-diaminopivalic acid scaffold.
Ruiz-Sánchez, Antonio Jesús; Mesa-Antúnez, Pablo; Barbero, Nekane; Collado-Martín, Daniel; Vida-Pol, Yolanda; Nájera-Albendín, Francisco; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (RSC publication, 2015-03-09)
Over recent years the importance of dendrimers has continued to increase in both life and material sciences. Multiple chemical strategies have been described toward the preparation of dendrimeric structures. Here, we present ... -
Synthesis of Amino Terminal Clicked dendrimers. Approaches to the application as a biomarker
Molina, Noemí; Nájera-Albendín, Francisco; Guadix-Domínguez, Juan Antonio; perez-pomarez, Jose M; Vida-Pol, Yolanda; Perez-Inestrosa, Ezequiel[et al.] (ACS Publications, 2019)
Herein, we present an easy and efficient synthesis of amino terminal dendrons, combining protection/deprotection reactions with copper-catalyzed azide alkyne cycloaddition in a convergent way. This new approach affords ... -
Synthesis of fluorescent dendrimeric antigen efficiently internalized by human dendritic cells
Mesa-Antunez, Pablo; Collado-Martín, Daniel; Vida-Pol, Yolanda; Nájera-Albendín, Francisco; Fernández-Duarte, Tahía Diana; Torres-Jaén, María Josefa; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (Servicio de Publicaciones de la Universidad de Huelva, 2016)
A new fluorescent dendrimeric antigen (DeAn) based on a dendron with amoxicilloyl terminal groups has been synthetized. The synthesis implies a novel class of all-aliphatic polyamide dendrimer (BisAminoalkylPolyAmide ...