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Listar por autor "Béjar-Alvarado, Julia"
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Genomic characterization and transcription analysis of European sea bass (Dicentrarchus labrax) rtp3 genes
Moreno-García, Patricia; Gémez-Mata, Juan; Álvarez-Torres, Daniel; García-Rosado, Esther; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (Elsevier, 2023-10-23)Fish RTP3, belonging to the receptor-transporting protein family, display several functions, including a putative antiviral role as virus-responsive gene. In this work, we have identified and characterized two different ... -
Genomic characterization and transcription analysis of European sea bass (Dicentrarchus labrax) rtp3 genes.
Moreno, Patricia; Gémez-Mata, Juan; Álvarez-Torres, Daniel; García-Rosado, Esther; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (Elsevier, 2023-10-23)Fish RTP3, belonging to the receptor-transporting protein family, display several functions, including a putative antiviral role as virus-responsive gene. In this work, we have identified and characterized two different ... -
Gilthead seabream (Sparus aurata) Mx proteins show positive and negative synergy in their antiviral activity
Fernández-Trujillo, M. Alejandra; García-Rosado, Esther; Alonso-Sánchez, María del Carmen; Borrego-García, Juan José; Álvarez-Herrero, María del Carmen; Béjar-Alvarado, Julia[et al.] (2014-10-07)Due to their direct antiviral activity, Mx proteins play a main role in the response mediated by the type I interferon against viral infections. The study of the farmed fish gilthead seabream Mx genes is specially interesting, ... -
Inducción de las proteínas Mx por interferón tipo I en células de dorada y de trucha
Béjar-Alvarado, Julia; Núñez, Encarnación; Fernández-Trujillo, M. Alejandra; Álvarez-Herrero, María del Carmen (2015-10-26)Characterizing the innate immune system defence mechanisms is essential to develop preventive measures against viral infections in aquaculture. In this study, the intra-specific differential response of Mx proteins to type ... -
Inhibition of nervous necrosis virus replication by Shewanella putrefaciens Pdp11 extract
Moreno, Patricia; Álvarez-Torres, Daniel; Balebona-Accino, María del Carmen; Domínguez-Maqueda, Marta; Moriñigo-Gutiérrez, Miguel Ángel; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen; García-Rosado, Esther[et al.] (Elsevier, 2023)One of the most relevant infectious diseases affecting farmed fish is the viral encephalopathy and retinopathy, caused by the nervous necrosis virus (NNV). The two commercial vaccines available against this virus have been ... -
Instituto de Biotecnología y Desarrollo Azul de la Universidad de Málaga, IBYDA: un instrumento al servicio de la docencia transversal de la economía circular
El desarrollo, a escala mundial, camina de un modelo de Economía lineal a uno circular o azul, que dé respuesta a los importantes desafíos económicos y ambientales de nuestro planeta. En 2015, la Comisión Europea ... -
Instituto de Biotecnología y Desarrollo Azul de la Universidad de Málaga: una apuesta por una Acuicultura Azul
Béjar-Alvarado, Julia; Bañares-España, Elena; Salas-Casanova, María del Carmen; Arijo-Andrade, Salvador; Alemany-Arrebola, Luis José; Reul, Andreas; García-Lafuente, Jesús; Galacho-Jiménez, Federico Benjamín; Zamora-Roselló, Mª Remedios; Ruiz-Molina, Antonio; Macías-Sánchez, Jorge; López-Figueroa, Félix[et al.] (2019-05-16)Noventa investigadores de la Universidad de Málaga pertenecientes a 21 grupos de investigación, se han organizado en un Instituto de Biotecnología y Desarrollo Azul, IBYDA. El objetivo del IBYDA es la investigación, la ... -
Juvenile gilthead sea bream immune response against RGNNV or RGNNV/SJNNV infections
Gémez-Mata, Juan; Moreno Garcia, Patricia; Álvarez-Torres, Daniel; García-Rosado, Esther; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (Sociedad Española de Virología, 2024-09-02)Viral nervous necrosis is one of the main threats for the aquaculture. It is caused by the nervous necrosis virus (NNV), with a genome composed of two positive-sense, ssRNA segments: RNA1, encoding the viral polymerase; ... -
Mx Protein involvement in the innate immune system against viral infections in Senegalese Sole (Solea senegalensis)
Álvarez-Torres, Daniel (Universidad de Málaga, Servicio de Publicaciones y Divulgación Científica, 2014)La acuicultura es una actividad de gran interés económico y ecológico, que presenta un alto potencial de crecimiento, y cuyo desarrollo sostenible constituye la vía óptima de aprovechamiento de los recursos pesqueros sin ... -
Nodavirus-host interplay: what we know and what is next.
Moreno, Patricia; Álvarez-Torres, Daniel; García-Rosado, Esther; Alonso-Sánchez, María del Carmen; Béjar-Alvarado, Julia (2024)Nervous necrosis virus (NNV) is a bisegmented ssRNA virus that is classified into four species: SJNNV, RGNNV, TPNNV and BFNNV. NNV causes viral nervous necrosis, a disease that affects farmed fish worldwide and in the ... -
Polimorfismos en la MxB de lubina (Dicentrarchus labrax) y susceptibilidad a VNNV
Novel, Patricia; Fernández, Jesús; Porta, Javier; Álvarez-Herrero, María del Carmen; Béjar-Alvarado, Julia (2013-10-01)La resistencia a las enfermedades es uno de los caracteres más interesantes en los programas de mejora genética en acuicultura. Las proteínas Mx son elementos clave en el estado antiviral desencadenado por el interferón ... -
Polisacáridos de Porphyridium cruentum presentan actividad antiviral diferencial frente a infecciones causadas de VHSV y VNN
Moreno Garcia, Patricia; Parra-Riofrio, Geovanna; Abdala-Díaz, Roberto Teófilo; García-Rosado, Esther; Uribe-Tapia, Eduardo; Alonso-Sánchez, María del Carmen; Béjar-Alvarado, Julia[et al.] (Sociedad Española de Microbiología, 2021)Los microorganismos del medio marino constituyen una importante fuente de compuestos cuya utilización en la prevención y/o tratamiento de enfermedades de etiología viral está siendo sugerida en los últimos años. En concreto, ... -
Senegalese sole (Solea senegalensis) ISG15: molecular characterization and in vivo interplay with viral infections
Álvarez-Torres, Daniel; Podadera, Ana María; Bandín Matos, Isabel; Béjar-Alvarado, Julia; García-Rosado, Esther; Alonso-Sánchez, María del Carmen[et al.] (2015-09-17)The interferon-stimulated gene 15 (Isg15) is strongly induced by type I interferon (IFN I), viral infection, and double-stranded RNA (poly I:C) in several fish species, suggesting that Isg15 protein could play a key role ... -
Setting out zebrafish (Danio rerio) as a model to study nervous necrosis virus-host interaction.
Moreno-García, Patricia; Álvarez-Torres, Daniel; Frétaud, Maxence; Mehraz, Manon; Langevin, Christelle; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (2023)Viral nervous necrosis is responsible for important economic losses in aquaculture facilities. The causative agent is the nervous necrosis virus (NNV). Four NNV species have been described, although only RGNNV and SJNNV ... -
Shewanella putrefaciens Pdp11 extracts promote European sea bass resistance against RGNNV infection.
Moreno-García, Patricia; Álvarez-Torres, Daniel; Gémez-Mata, Juan; Balebona-Accino, María del Carmen; Domínguez-Maqueda, Marta; Cerezo-Domínguez, Ana Isabel; Moriñigo-Gutiérrez, Miguel Ángel; Béjar-Alvarado, Julia; García-Rosado, Esther; Alonso-Sánchez, María del Carmen[et al.] (2024)The viral nervous necrosis (VNN) is a neurotropic disease affecting different fish species, resulting in high mortality rates. The causal agent is the nervous necrosis virus (NNV), belonging to the Betanodavirus genus, ... -
Shewanella putrefaciens Pdp11 extracts protect against betanodavirus infection.
Moreno-García, Patricia; Álvarez-Torres, Daniel; Balebona-Accino, María del Carmen; Moriñigo-Gutiérrez, Miguel Ángel; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen; García-Rosado, Esther[et al.] (2023)Viral nervous necrosis is caused by the nervous necrosis virus (Betanodavirus genus), a naked virus with two positive-sense RNA segments. Betanodaviruses are classified into four species, being RGNNV predominant in the ... -
El sistema del interferón tipo I protege a juveniles de lenguado senegalés (Solea senegalensis) frente a la infección por VHSV
Álvarez-Torres, Daniel; Podadera, AM; Vieytes, Lisandro P; Souto, S; Bandin, S; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen; García-Rosado, Esther[et al.] (2014-09-25)El lenguado senegalés (Solea senegalensis) es susceptible a la infección por el Virus de la Septicemia Hemorrágica Viral (VHSV) bajo condiciones experimentales. El objetivo de este trabajo es determinar el papel del sistema ... -
Tetraselmis suecica and Porphyridium cruentum exopolysaccharides show anti-VHSV activity on RTG-2 cells
Parra-Riofrio, Geovanna; Moreno, Patricia; García-Rosado, Esther; Alonso-Sánchez, María del Carmen; Uribe-Tapia, Eduardo; Abdala-Díaz, Roberto Teófilo; Béjar-Alvarado, Julia[et al.] (Springer, 2023)The use of functional feed additives is an important approach to both, prevent and fight, viral diseases in aquaculture. In this regard, microalgae-derived products, and, more specifically, microalgal exopolysaccharides ... -
The Senegalese Sole Mx gene promoter contains a variable microsatellite region involved in the transcriptional
Álvarez-Torres, Daniel; Vieytes, Lisandro P; García-Rosado, Esther; Alonso-Sánchez, María del Carmen; Béjar-Alvarado, Julia (2015-09-14)Interferons (IFNs) play a key role against viral infections by stimulating the expression of IFN stimulated genes, such as Mx. The transcriptional regulation of these genes in fish are poorly understood. The sequencing ... -
Transcriptional profile and serological studies of the European sea bass immune response against betanodavirus infections
Moreno, Patricia; López-Jimena, Benjamín; Scapigliati, Giuseppe; Buonocuore, Francesco; García-Rosado, Esther; Borrego-García, Juan José; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (2019-07-19)European sea bass is highly affected by outbreaks of viral nervous necrosis disease, provoked by the nervous necrosis virus (NNV). This virus displays a positive-sense RNA genome composed of two segments, RNA1, encoding ...