Listar por autor "Montalban, Xavier"
Mostrando ítems 1-5 de 5
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Decreased soluble IFN-β receptor (sIFNAR2) in multiple sclerosis patients: A potential serum diagnostic biomarker
Órpez-Zafra, Teresa; Pavía-Molina, José
; Hurtado-Guerrero, Isaac; Pinto-Medel, Maria Jesús; Rodríguez-Bada, José Luis; Urbaneja, Patricia; Suardíaz García, Margarita; Villar, Luisa M; Comabella, Manuel; Montalban, Xavier; Alvarez-Cermeño, Jose C; Leyva-Fernández, Laura; Fernández-Fernández, Óscar; Oliver-Martos, Begoña[et al.] (SAGE Journals, 2017)
Background: The soluble isoform of the interferon-β (IFN-β) receptor (sIFNAR2) could modulate the activity of both endogenous and systemically administered IFN-β. Previously, we described lower serum sIFNAR2 levels in ... -
Identification of a functional variant in the KIF5A-CYP27B1-METTL1-FAM119B locus associated with multiple sclerosis.
Alcina, Antonio; Fedetz, María; Fernández, Óscar; Saiz, Albert; Izquierdo, Guillermo; Lucas, Miguel; Leyva-Fernández, Laura; García-León, Juan Antonio; Abad-Grau, María del Mar; Alloza, Iraide; Antigüedad, Alfredo; Garcia-Barcina, María Jesús; Vandenbroeck, Koen; Varadé, Jezabel; de la Hera, Belén; Arroyo, Rafael; Comabella, Manuel; Montalban, Xavier; Petit-Marty, Natalia; Navarro, Arcadi; Otaegui, David; Olascoaga, Javier; Blanco, Yolanda; Urcelay, Elena; Matesanz, Fuencisla[et al.] (BMJ Journals, 2013-01)
Background and aim: Several studies have highlighted the association of the 12q13.3-12q14.1 region with coeliac disease, type 1 diabetes, rheumatoid arthritis and multiple sclerosis (MS); however, the causal variants ... -
NLRP3 inflammasome as prognostic factor and therapeutic target in primary progressive multiple sclerosis patients
Malhotra, Sunny; Costa, Carme; Eixarch, Herena; Keller, Christian W; Lukas Amman, Lukas; Martínez-Banaclocha, Helios; Midaglia, Luciana; Sarró, Eduard; Isabel Machín-Díaz, Isabel; M Villar, Luisa; Triviño, Juan Carlos; Oliver-Martos, Begoña; Navarro Parladé, Laura; Calvo-Barreiro, Laura; Matesanz, Fuencisla; Vandenbroeck, Koen; Urcelay, Elena; María-Luisa Martínez-Ginés, María-Luisa; Tejeda-Velarde, Amalia; Fissolo, Nicolás; Castilló, Joaquín; Sanchez, Alex; Robertson, Avril A B; Clemente, Diego; Prinz, Marco; Pelegrin, Pablo; Lünemann, Jan D; Espejo, Carmen; Montalban, Xavier; Comabella, Manuel[et al.] (Oxford Academic, 2020)
Primary progressive multiple sclerosis is a poorly understood disease entity with no specific prognostic biomarkers and scarce therapeutic options. We aimed to identify disease activity biomarkers in multiple sclerosis by ... -
NLRP3 inflammasome is associated with the response to IFN-β in patients with multiple sclerosis
Malhotra, Sunny; Rio, Jordi; Urcelay, Elena; Nurtdinov, Ramil; F Bustamante, Marta; Fernández Fernández, Óscar; Oliver-Martos, Begoña; Zettl, Uwe; Brassat, David; Killestein, Joep; Lechner-Scott, Jeannette; Drulovic, Jelena; Chan, Andrew; Martinelli-Boneschi, Filippo; García-Merino, Antonio; Montalban, Xavier; Comabella, Manuel[et al.] (2015)
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The autoimmune disease-associated KIF5A, CD226 and SH2B3 gene variants confer susceptibility for multiple sclerosis.
Alcina, Antonio; Vandenbroeck, Köen; Otaegui, David; Saiz, Alberto; González, José Ramón; Fernández Fernández, Óscar; Cavanillas, María L; Cénit, María C; Arroyo, Rafael; Alloza, Iraide; Garcia-Barcina, María; Antigüedad, Alfredo; Leyva-Fernández, Laura; Izquierdo, Guillermo; Lucas, Miguel; Fedetz, María; Pinto-Medel, María Jesús; Olascoaga, Javier; Blanco, Yolanda; Comabella, Manuel; Montalbán, Xavier; Urcelay, Elena; Matesanz, Fuencisla[et al.] (Springer Nature, 2010)
Genome-wide association studies (GWAS) have revealed that different diseases share susceptibility variants. Twelve single- nucleotide polymorphisms (SNPs) previously associated with different immune-mediated diseases in ...