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Systemic blockade of LPA1/3 lysophosphatidic acid receptors by ki16425 modulates the effects of ethanol on the brain and behavior
Sánchez-Marín, Laura; Ladrón de Guevara-Miranda, David; Mañas-Padilla, María del Carmen; Alén, Francisco; Moreno-Fernández, Román D.; Díaz-Navarro, Caridad; Pérez-del Palacio, José; García-Fernández, María Inmaculada; Pedraza-Benítez, María del Carmen
; Pavón, Francisco Javier; Rodríguez de Fonseca, Fernando; Santín-Núñez, Luis Javier
; Serrano, Antonia; Castilla-Ortega, María Estela
[et al.] (Elsevier, 2018-05-01)
The systemic administration of lysophosphatidic acid (LPA) LPA1/3 receptor antagonists is a promising clinical tool for cancer, sclerosis and fibrosis-related diseases. Since LPA1 receptor-null mice engage in increased ...